Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Matthias Weigel"'
Autor:
Muhamed Barakovic, Matthias Weigel, Alessandro Cagol, Sabine Schaedelin, Riccardo Galbusera, Po-Jui Lu, Xinjie Chen, Lester Melie-Garcia, Mario Ocampo-Pineda, Erik Bahn, Christine Stadelmann, Marco Palombo, Ludwig Kappos, Jens Kuhle, Stefano Magon, Cristina Granziera
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Pathological data showed focal inflammation and regions of diffuse neuronal loss in the cortex of people with multiple sclerosis (MS). In this work, we applied a novel model (“soma and neurite density imaging (SANDI)”) to multishell diff
Externí odkaz:
https://doaj.org/article/71285021003c4428bcde1d1650746e4e
Autor:
Martina Greselin, Po-Jui Lu, Lester Melie-Garcia, Mario Ocampo-Pineda, Riccardo Galbusera, Alessandro Cagol, Matthias Weigel, Nina de Oliveira Siebenborn, Esther Ruberte, Pascal Benkert, Stefanie Müller, Sebastian Finkener, Jochen Vehoff, Giulio Disanto, Oliver Findling, Andrew Chan, Anke Salmen, Caroline Pot, Claire Bridel, Chiara Zecca, Tobias Derfuss, Johanna M. Lieb, Michael Diepers, Franca Wagner, Maria I. Vargas, Renaud Du Pasquier, Patrice H. Lalive, Emanuele Pravatà, Johannes Weber, Claudio Gobbi, David Leppert, Olaf Chan-Hi Kim, Philippe C. Cattin, Robert Hoepner, Patrick Roth, Ludwig Kappos, Jens Kuhle, Cristina Granziera
Publikováno v:
Bioengineering, Vol 11, Iss 8, p 858 (2024)
The detection of contrast-enhancing lesions (CELs) is fundamental for the diagnosis and monitoring of patients with multiple sclerosis (MS). This task is time-consuming and suffers from high intra- and inter-rater variability in clinical practice. Ho
Externí odkaz:
https://doaj.org/article/753b7b7b06c042a89d9dbeabe7219d4d
Autor:
Federico Spagnolo, Susanna Gobbi, Enikő Zsoldos, Manon Edde, Matthias Weigel, Cristina Granziera, Maxime Descoteaux, Muhamed Barakovic, Stefano Magon
Publikováno v:
Frontiers in Neuroimaging, Vol 3 (2024)
IntroductionMulti-shell diffusion Magnetic Resonance Imaging (dMRI) data has been widely used to characterise white matter microstructure in several neurodegenerative diseases. The lack of standardised dMRI protocols often implies the acquisition of
Externí odkaz:
https://doaj.org/article/565cd9842baf47a6836c097dcd633f54
Autor:
Sara Bosticardo, Simona Schiavi, Sabine Schaedelin, Matteo Battocchio, Muhamed Barakovic, Po-Jui Lu, Matthias Weigel, Lester Melie-Garcia, Cristina Granziera, Alessandro Daducci
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2024)
IntroductionRecent studies showed that the myelin of the brain changes in the life span, and demyelination contributes to the loss of brain plasticity during normal aging. Diffusion-weighted magnetic resonance imaging (dMRI) allows studying brain con
Externí odkaz:
https://doaj.org/article/978e6d0e329e46579d0876519e4bbe82
Autor:
A. L. Wenger, Muhamed Barakovic, Sara Bosticardo, Sabine Schaedelin, Alessandro Daducci, Simona Schiavi, Matthias Weigel, Reza Rahmanzadeh, Po-Jui Lu, Alessandro Cagol, Ludwig Kappos, Jens Kuhle, Pasquale Calabrese, Cristina Granziera
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
IntroductionThe presence of focal cortical and white matter damage in patients with multiple sclerosis (pwMS) might lead to specific alterations in brain networks that are associated with cognitive impairment. We applied microstructure-weighted conne
Externí odkaz:
https://doaj.org/article/00b79015a65f42ae8270c6dafd774716
Autor:
Xinjie Chen, Sabine Schädelin, Po-Jui Lu, Mario Ocampo-Pineda, Matthias Weigel, Muhamed Barakovic, Esther Ruberte, Alessandro Cagol, Benedicte Marechal, Tobias Kober, Jens Kuhle, Ludwig Kappos, Lester Melie-Garcia, Cristina Granziera
Publikováno v:
NeuroImage: Clinical, Vol 37, Iss , Pp 103349- (2023)
Objectives and aims: Quantitative MRI (qMRI) has greatly improved the sensitivity and specificity of microstructural brain pathology in multiple sclerosis (MS) when compared to conventional MRI (cMRI). More than cMRI, qMRI also provides means to asse
Externí odkaz:
https://doaj.org/article/9b9de24565e7496eb8847da9dce1a7e3
Autor:
Matthias Weigel, Peter Dechent, Riccardo Galbusera, Erik Bahn, Govind Nair, Po-Jui Lu, Ludwig Kappos, Wolfgang Brück, Christine Stadelmann, Cristina Granziera
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Postmortem magnetic resonance imaging (MRI) of the fixed healthy and diseased human brain facilitates spatial resolutions and image quality that is not achievable with in vivo MRI scans. Though challenging—and almost exclusively performed
Externí odkaz:
https://doaj.org/article/450a8cb7872b40bf91203d860adc91df
Autor:
Simona Schiavi, Po-Jui Lu, Matthias Weigel, Antoine Lutti, Derek K. Jones, Ludwig Kappos, Cristina Granziera, Alessandro Daducci
Publikováno v:
NeuroImage, Vol 249, Iss , Pp 118922- (2022)
To date, we have scarce information about the relative myelination level of different fiber bundles in the human brain. Indirect evidence comes from postmortem histology data but histological stainings are unable to follow a specific bundle and deter
Externí odkaz:
https://doaj.org/article/ff8bdfdfd0f74da3b05820bd8e599ac0
Autor:
Reza Rahmanzadeh, Matthias Weigel, Po-Jui Lu, Lester Melie-Garcia, Thanh D. Nguyen, Alessandro Cagol, Francesco La Rosa, Muhamed Barakovic, Antoine Lutti, Yi Wang, Meritxell Bach Cuadra, Ernst-Wilhelm Radue, Laura Gaetano, Ludwig Kappos, Jens Kuhle, Stefano Magon, Cristina Granziera
Publikováno v:
NeuroImage: Clinical, Vol 36, Iss , Pp 103177- (2022)
Introduction: Multiple Sclerosis (MS) is a common neurological disease primarily characterized by myelin damage in lesions and in normal - appearing white and gray matter (NAWM, NAGM).Several quantitative MRI (qMRI) methods are sensitive to myelin ch
Externí odkaz:
https://doaj.org/article/ec6e1061080940918ced1fdde2edde32
Autor:
Po-Jui Lu, Muhamed Barakovic, Matthias Weigel, Reza Rahmanzadeh, Riccardo Galbusera, Simona Schiavi, Alessandro Daducci, Francesco La Rosa, Meritxell Bach Cuadra, Robin Sandkühler, Jens Kuhle, Ludwig Kappos, Philippe Cattin, Cristina Granziera
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Conventional magnetic resonance imaging (cMRI) in multiple sclerosis (MS) patients provides measures of focal brain damage and activity, which are fundamental for disease diagnosis, prognosis, and the evaluation of response to therapy. However, cMRI
Externí odkaz:
https://doaj.org/article/7fff166b0b9e408f8932ca244105ed18