Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Matthias W.G. Zeller"'
Autor:
Negin Jalali Motlagh, John W. Chen, Gregory R. Wojtkiewicz, Cuihua Wang, Stephan Schmidt, Yue Wu, Matthias W.G. Zeller, Benjamin Pulli, Anning Li
Publikováno v:
Theranostics
Aberrant innate immune response drives the pathophysiology of many diseases. Myeloperoxidase (MPO) is a highly oxidative enzyme secreted by activated myeloid pro-inflammatory immune cells such as neutrophils and macrophages, and is a key mediator of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9a80a7bbdea120a501362bd2c09eb52
https://doi.org/10.7150/thno.36264
https://doi.org/10.7150/thno.36264
Autor:
Gregory R. Wojtkiewicz, John W. Chen, Negin Jalali Motlagh, Cuihua Wang, Kevin P. Maresca, Edmund J. Keliher, Matthias W.G. Zeller, Matthias Nahrendorf, Hye-Yeong Kim, Jianqing Chen, Maaz S. Ahmed, Aaron D. Aguirre, Leonard Buckbinder
Myeloperoxidase (MPO) is a critical proinflammatory enzyme implicated in cardiovascular, neurological, and rheumatological diseases. Emerging therapies targeting inflammation have raised interest in tracking MPO activity in patients. We describe 18 F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ddc10e5d3f11439e614ed43d3bf2022
https://europepmc.org/articles/PMC6575581/
https://europepmc.org/articles/PMC6575581/
Autor:
Katrin Deumelandt, Michael Platten, Jana K. Sonner, Martin Bendszus, Klara Kirschbaum, Julia Bode, Angelika Hoffmann, Thomas Krüwel, Manuel Fischer, Matthias W.G. Zeller, Sabine Heiland, Rakesh Sharma, Michael O. Breckwoldt, Martina U. Muckenthaler, John W. Chen, Wolfgang Wick, Björn Tews, Milene Costa da Silva
Publikováno v:
Proceedings of the National Academy of Sciences. 113:13227-13232
Innate immune cells play a key role in the pathogenesis of multiple sclerosis and experimental autoimmune encephalomyelitis (EAE). Current clinical imaging is restricted to visualizing secondary effects of inflammation, such as gliosis and blood-brai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f799491318b1308ceffa37cfbac44b9
https://doi.org/10.1073/pnas.1609397113
https://doi.org/10.1073/pnas.1609397113
Autor:
Zhenwei Yao, Benjamin Pulli, Grant K. Lewandrowski, Bakhos A. Tannous, John W. Chen, Anning Li, Jenny J. Linnoila, Xiaoyuan Feng, Matthias W.G. Zeller, Yue Wu, Muhammad Ali, Benoit Tricot, Edmund J. Keliher, Jing-Hui Li, Giulia Fulci, Gregory R. Wojtkiewicz, Cuihua Wang
Publikováno v:
Cancer Immunology, Immunotherapy. 65:1545-1554
Currently, there is no stable and flexible method to label and track cytotoxic T-lymphocytes (CTLs) in vivo in CTL immunotherapy. We aimed to evaluate whether the sulfo-hydroxysuccinimide (NHS)-biotin-streptavidin (SA) platform could chemically modif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d241528d1a408f6e72e8777d3f5a3c3e
https://doi.org/10.1007/s00262-016-1911-9
https://doi.org/10.1007/s00262-016-1911-9
Autor:
John W. Chen, Lionel Bure, Ricard Masia, Yuri Choi, A.R. Guimaraes, Yoshiko Iwamoto, Benjamin Pulli, Gregory R. Wojtkiewicz, Cuihua Wang, Muhammad Ali, Matthias W.G. Zeller, Kathleen E. Corey
Publikováno v:
Radiology. 284(2)
Purpose To test whether MPO-Gd, an activatable molecular magnetic resonance (MR) imaging agent specific for myeloperoxidase (MPO) activity, could detect MPO activity in nonalcoholic steatohepatitis (NASH) mouse models and human liver biopsy samples.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8bf90785bee73032e62ea803f25ea10
https://pubmed.ncbi.nlm.nih.gov/28358240
https://pubmed.ncbi.nlm.nih.gov/28358240
Autor:
Matthias W.G. Zeller, Jesús Planagumà, Radha P. Narsimhan, Benjamin Pulli, John W. Chen, Stefan Schob, Josep Dalmau, Jenny J. Linnoila, Thaís Armangue
Publikováno v:
Neurology® Neuroimmunology & Neuroinflammation
ObjectiveTo develop an endogenous rodent model of postinfectious anti-NMDA receptor (NMDAR) encephalitis.MethodsSix mice were inoculated intranasally with herpes simplex virus (HSV) 1 and subsequently treated with acyclovir for 2 weeks. Serum was col
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28d31a255cc9b452c82939631542c6d6
https://doi.org/10.1212/nxi.0000000000000529
https://doi.org/10.1212/nxi.0000000000000529
Autor:
Po-Shun Lee, Yuk-Ming Tsang, Hsieh Kevin Li-Chun, Matthias W.G. Zeller, Stefan Schob, Cuihua Wang, John W. Chen, Thomas P. Stossel, Muhammad Ali, Benjamin Pulli, Terry Ting-Yu Chiou
Gelsolin is the fourth most abundant protein in the body and its depletion in the blood has been found in multiple sclerosis (MS) patients. How gelsolin affects the MS brain has not been studied. We found that while the secreted form of gelsolin (pGS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76442a9f430e5f65adae850d8e750e4c
https://europepmc.org/articles/PMC4595933/
https://europepmc.org/articles/PMC4595933/