Zobrazeno 1 - 10
of 10 839
pro vyhledávání: '"Matthias W"'
Autor:
Lucía Álvarez, Kevin Haubrich, Louisa Iselin, Laurent Gillioz, Vincenzo Ruscica, Karine Lapouge, Sandra Augsten, Ina Huppertz, Nila Roy Choudhury, Bernd Simon, Pawel Masiewicz, Mathilde Lethier, Stephen Cusack, Katrin Rittinger, Frank Gabel, Alexander Leitner, Gracjan Michlewski, Matthias W. Hentze, Frédéric H. T. Allain, Alfredo Castello, Janosch Hennig
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract TRIM25 is an RNA-binding ubiquitin E3 ligase with central but poorly understood roles in the innate immune response to RNA viruses. The link between TRIM25’s RNA binding and its role in innate immunity has not been established. Thus, we ut
Externí odkaz:
https://doaj.org/article/d8245675d28e4b2bbc482fdb79f08563
Autor:
Edward H. Lee, Michelle Han, Jason Wright, Michael Kuwabara, Jacob Mevorach, Gang Fu, Olivia Choudhury, Ujjwal Ratan, Michael Zhang, Matthias W. Wagner, Robert Goetti, Sebastian Toescu, Sebastien Perreault, Hakan Dogan, Emre Altinmakas, Maryam Mohammadzadeh, Kathryn A. Szymanski, Cynthia J. Campen, Hollie Lai, Azam Eghbal, Alireza Radmanesh, Kshitij Mankad, Kristian Aquilina, Mourad Said, Arastoo Vossough, Ozgur Oztekin, Birgit Ertl-Wagner, Tina Poussaint, Eric M. Thompson, Chang Y. Ho, Alok Jaju, John Curran, Vijay Ramaswamy, Samuel H. Cheshier, Gerald A. Grant, S. Simon Wong, Michael E. Moseley, Robert M. Lober, Mattias Wilms, Nils D. Forkert, Nicholas A. Vitanza, Jeffrey H. Miller, Laura M. Prolo, Kristen W. Yeom
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract While multiple factors impact disease, artificial intelligence (AI) studies in medicine often use small, non-diverse patient cohorts due to data sharing and privacy issues. Federated learning (FL) has emerged as a solution, enabling training
Externí odkaz:
https://doaj.org/article/34ebed521a7c4e708c0cd4dc5896d5a1
Autor:
Annika Engel, Nicole Ludwig, Friederike Grandke, Viktoria Wagner, Fabian Kern, Tobias Fehlmann, Georges P. Schmartz, Ernesto Aparicio-Puerta, Dominic Henn, Barbara Walch-Rückheim, Matthias Hannig, Stefan Rupf, Eckart Meese, Matthias W. Laschke, Andreas Keller
Publikováno v:
RNA Biology, Vol 21, Iss 1, Pp 31-44 (2024)
Non-thermal plasma, a partially ionized gas, holds significant potential for clinical applications, including wound-healing support, oral therapies, and anti-tumour treatments. While its applications showed promising outcomes, the underlying molecula
Externí odkaz:
https://doaj.org/article/0f8aeea9ae554d44837d51695cf68609
Autor:
Kareem Kudus, Matthias W. Wagner, Khashayar Namdar, Julie Bennett, Liana Nobre, Uri Tabori, Cynthia Hawkins, Birgit Betina Ertl-Wagner, Farzad Khalvati
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract The use of targeted agents in the treatment of pediatric low-grade gliomas (pLGGs) relies on the determination of molecular status. It has been shown that genetic alterations in pLGG can be identified non-invasively using MRI-based radiomic
Externí odkaz:
https://doaj.org/article/fa7cfa07525c405ca9a31558b2c4db19
Autor:
Antonios E. Spiliotis, Sebastian Holländer, Gudrun Wagenpfeil, Robert Eisele, Spyridon Nika, Orestis Mallis Kyriakides, Matthias W. Laschke, Michael D. Menger, Matthias Glanemann, Gereon Gäbelein
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Electrochemotherapy (ECT) combines the reversible electroporation (rEP) with intravenous (i.v.) or intratumoral (i.t.) administration of chemotherapeutic drugs. We conducted this study to compare the efficacy of i.v., i.t., and i.v. + i.t. i
Externí odkaz:
https://doaj.org/article/859d9752226c4cfba6390a0dd6b82156
Autor:
Peter A. Fasching, Chunling Hu, Steven N. Hart, Matthias Ruebner, Eric C. Polley, Rohan D. Gnanaolivu, Andreas D. Hartkopf, Hanna Huebner, Wolfgang Janni, Peyman Hadji, Hans Tesch, Sabrina Uhrig, Johannes Ettl, Michael P. Lux, Diana Lüftner, Markus Wallwiener, Lena A. Wurmthaler, Chloë Goossens, Volkmar Müller, Matthias W. Beckmann, Alexander Hein, Daniel Anetsberger, Erik Belleville, Pauline Wimberger, Michael Untch, Arif B. Ekici, Hans-Christian Kolberg, Arndt Hartmann, Florin-Andrei Taran, Tanja N. Fehm, Diethelm Wallwiener, Sara Y. Brucker, Andreas Schneeweiss, Lothar Häberle, Fergus J. Couch
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-7 (2024)
Abstract Germline mutations in BRCA1 and BRCA2 (gBRCA1/2) are required for a PARP inhibitor therapy in patients with HER2-negative (HER2−) advanced breast cancer (aBC). However, little is known about the prognostic impact of gBRCA1/2 mutations in a
Externí odkaz:
https://doaj.org/article/7fc65e7d8ec9445caafcbb4945b9c522
Publikováno v:
Environmental Sciences Europe, Vol 36, Iss 1, Pp 1-12 (2024)
Abstract Background Due to climate change, extreme weather events are becoming more frequent worldwide. An example of such an extreme weather event was the flooding in Western Europe in July 2021. Currently, there are large research gaps regarding ho
Externí odkaz:
https://doaj.org/article/a92532e154664ee3a0b29044e9a28029
Autor:
Annika Krückel, Miriam Saatze, Annika S. Behrens, Matthias W. Beckmann, Patrik Pöschke, Julius Emons
Publikováno v:
Gynecologic Oncology Reports, Vol 55, Iss , Pp 101503- (2024)
Background: Deficiencies in the merging process of the paramesonephric ducts as part of the embryonal development lead to anomalies of the uterus, cervix, fallopian tubes and proximal vagina (Müllerian malformations). The co-occurrence with cervical
Externí odkaz:
https://doaj.org/article/9da6b29c56f04f8e88366a11f191ba24
Autor:
Selina Wrublewsky, Jessica Schultz, Tekoshin Ammo, Caroline Bickelmann, Wolfgang Metzger, Thomas Später, Tim Pohlemann, Michael D. Menger, Matthias W. Laschke
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
IntroductionSpheroids are promising building blocks for scaffold-free bone tissue engineering. Their rapid vascularization is of major importance to guarantee their survival after transplantation. To achieve this, we herein introduce the biofabricati
Externí odkaz:
https://doaj.org/article/06b42bc3fb0847c792bef8ea78f059ba
Publikováno v:
BJPsych Open, Vol 10 (2024)
Background The Mini-Mental State Examination (MMSE) is a composite scale that is included in diagnostic algorithms and in procedures to assess severity of cognitive impairment and efficacy of therapeutic interventions. It is unclear, however, whether
Externí odkaz:
https://doaj.org/article/ae69ed1994974c55a7f8e891612a501d