Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Matthias Vandesquille"'
Autor:
Clémence Dudeffant, Matthias Vandesquille, Kelly Herbert, Clément M. Garin, Sandro Alves, Véronique Blanchard, Emmanuel E. Comoy, Fanny Petit, Marc Dhenain
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Gadolinium (Gd)-stained MRI is based on Gd contrast agent (CA) administration into the brain parenchyma. The strong signal increase induced by Gd CA can be converted into resolution enhancement to record microscopic MR images. Moreover, inho
Externí odkaz:
https://doaj.org/article/5e93a4a65928455e9bb7593b8b3d98c9
Autor:
Michael Green, Marie-Claude Asselin, Inga B. Fricke, Marco Mottinelli, Andreas H. Jacobs, Christopher R. McCurdy, Hervé Boutin, Andrew C Robinson, Michael Kassiou, David M. A. Mann, Samuel D. Banister, Matthias Vandesquille, Elizabeth Barnett, Christophe Mesangeau, Christian Prenant, Francois-Xavier Lepelletier
Publikováno v:
Theranostics
Lepelletier, F-X, Vandesquille, M, Asselin, M-C, Prenant, C, Robinson, A, Mann, D, Green, M, Barnett, E, Banister, S D, Mottinelli, M, Mesangeau, C, McCurdy, C R, Fricke, I, Jacobs, A H, Kassiou, M & Boutin, H 2020, ' Evaluation of 18F-IAM6067 as a sigma-1 receptor PET tracer for neurodegeneration in vivo in rodents and in human tissue ', Theranostics, pp. 7938-7955 . https://doi.org/10.7150/thno.47585
Lepelletier, F-X, Vandesquille, M, Asselin, M-C, Prenant, C, Robinson, A C, Mann, D M A, Green, M, Barnett, E, Banister, S D, Mottinelli, M, Mesangeau, C, McCurdy, C R, Fricke, I B, Jacobs, A H, Kassiou, M & Boutin, H 2020, ' Evaluation of F-18-IAM6067 as a sigma-1 receptor PET tracer for neurodegeneration in vivo in rodents and in human tissue ', Theranostics, vol. 10, no. 18, pp. 7938-7955 . https://doi.org/10.7150/thno.47585
Lepelletier, F-X, Vandesquille, M, Asselin, M-C, Prenant, C, Robinson, A, Mann, D, Green, M, Barnett, E, Banister, S D, Mottinelli, M, Mesangeau, C, McCurdy, C R, Fricke, I, Jacobs, A H, Kassiou, M & Boutin, H 2020, ' Evaluation of 18F-IAM6067 as a sigma-1 receptor PET tracer for neurodegeneration in vivo in rodents and in human tissue ', Theranostics, pp. 7938-7955 . https://doi.org/10.7150/thno.47585
Lepelletier, F-X, Vandesquille, M, Asselin, M-C, Prenant, C, Robinson, A C, Mann, D M A, Green, M, Barnett, E, Banister, S D, Mottinelli, M, Mesangeau, C, McCurdy, C R, Fricke, I B, Jacobs, A H, Kassiou, M & Boutin, H 2020, ' Evaluation of F-18-IAM6067 as a sigma-1 receptor PET tracer for neurodegeneration in vivo in rodents and in human tissue ', Theranostics, vol. 10, no. 18, pp. 7938-7955 . https://doi.org/10.7150/thno.47585
The sigma 1 receptor (S1R) is widely expressed in the CNS and is mainly located on the endoplasmic reticulum. The S1R is involved in the regulation of many neurotransmission systems and, indirectly, in neurodegenerative diseases. The S1R may therefor
Autor:
François-Xavier Lepelletier, Matthias Vandesquille, Marie-Claude Asselin, Christian Prenant, Andrew C Robinson, David M A Mann, Michael Green, Elizabeth Barnett, Samuel D Banister, Marco Mottinelli, Christophe Mesangeau, Christopher R McCurdy, Inga B Fricke, Andreas H. Jacobs, Michael Kassiou, Hervé Boutin
Publikováno v:
Theranostics. 12:5335-5336
Autor:
J.L. Ulloa, Hervé Boutin, Ben R Dickie, Matthias Vandesquille, Geoff J M Parker, Laura M. Parkes
Publikováno v:
Dickie, B R, Vandesquille, M, Ulloa, J, Boutin, H, Parkes, L M & Parker, G J M 2019, ' Water-exchange MRI detects subtle blood-brain barrier breakdown in Alzheimer's disease rats ', NeuroImage, vol. 184, pp. 349-358 . https://doi.org/10.1016/j.neuroimage.2018.09.030
Blood-brain barrier (BBB) breakdown has been hypothesized to play a key role in the onset and progression of Alzheimer's disease (AD). However, the question of whether AD itself contributes to loss of BBB integrity is still uncertain, as many in-vivo
Autor:
Johnny Vercouillie, Michael Kassiou, Karen Davies, Francisco R. López-Picón, Clovis Tauber, Llwyd David Orton, Anniina Snellman, Sylvie Chalon, Dervis A. Salih, Julie Busson, Aisling Chaney, Sylvain Routier, Matthias Vandesquille, Juha O. Rinne, Frédéric Buron, Hervé Boutin, Rui Wang, Michael K. Harte, Johanna Rokka, Christina Georgiadou, Tristan A. Reekie, Catherine E. Lawrence, Samuel David Webb, Stephen R. Williams, Daniela Bochicchio, Sophie Serrière, Frances A. Edwards
Publikováno v:
Theranostics
Mouse models of Alzheimer's disease (AD) are valuable but do not fully recapitulate human AD pathology, such as spontaneous Tau fibril accumulation and neuronal loss, necessitating the development of new AD models. The transgenic (TG) TgF344-AD rat h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c1a1486fea5b6684e7478cf0207e266
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-444788
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-444788
Publikováno v:
Immunology Letters
Immunology Letters, 2017, 188, pp.89-95. ⟨10.1016/j.imlet.2017.07.001⟩
Immunology Letters, Elsevier, 2017, 188, pp.89-95. ⟨10.1016/j.imlet.2017.07.001⟩
Immunology Letters, 2017, 188, pp.89-95. ⟨10.1016/j.imlet.2017.07.001⟩
Immunology Letters, Elsevier, 2017, 188, pp.89-95. ⟨10.1016/j.imlet.2017.07.001⟩
International audience; The two most used methods to select camelid single-domain antibody-fragments (VHHs) are: displaying their repertoires on the surface of filamentous bacteriophages (phage display) or linking them to ribosomes (ribosome display)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f762809b312cb93b02b629e8df0729b5
https://hal-pasteur.archives-ouvertes.fr/pasteur-01580563/file/1-s2.0-S0165247817301165-main(1).pdf
https://hal-pasteur.archives-ouvertes.fr/pasteur-01580563/file/1-s2.0-S0165247817301165-main(1).pdf
Autor:
Charles Duyckaerts, Christelle Ganneau, Fiona Grueninger, Clémence Dudeffant, Benoît Delatour, Pascal Lenormand, Marc Dhenain, Chrystelle Po, Matthias Vandesquille, Christian Czech, Sylvie Bay, Tengfei Li, Pierre Lafaye
Publikováno v:
mAbs
mAbs, 2017, 9 (6), pp.1016-1027. ⟨10.1080/19420862.2017.1342914⟩
mAbs, Taylor & Francis, 2017, 9 (6), pp.1016-1027. ⟨10.1080/19420862.2017.1342914⟩
mAbs, 2017, 9 (6), pp.1016-1027. ⟨10.1080/19420862.2017.1342914⟩
mAbs, Taylor & Francis, 2017, 9 (6), pp.1016-1027. ⟨10.1080/19420862.2017.1342914⟩
International audience; Today, molecular imaging of neurodegenerative diseases is mainly based on small molecule probes. Alternatively, antibodies are versatile tools that may be developed as new imaging agents. Indeed, they can be readily obtained t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a25c77679e16644f75ec995c3476eaf2
https://hal-pasteur.archives-ouvertes.fr/pasteur-01671738
https://hal-pasteur.archives-ouvertes.fr/pasteur-01671738
Autor:
Kelly Herbert, Sandro Alves, Clémence Dudeffant, Marc Dhenain, Emmanuel Comoy, Fanny Petit, Matthias Vandesquille
Publikováno v:
Alzheimer's & Dementia. 13
Autor:
Benoît Delatour, Ihsen Youssef, Tengfei Li, Christelle Ganneau, Pascal Lenormand, Matthias Vandesquille, Charles Duyckaerts, Pierre Lafaye, Fiona Grueninger, Uwe Maskos, Christian Czech, Clémence Dudeffant, Sylvie Bay, Marc Dhenain, Fani Koukouli
Publikováno v:
Journal of Controlled Release
Journal of Controlled Release, Elsevier, 2016, 243, pp.1-10. ⟨10.1016/j.jconrel.2016.09.019⟩
Journal of Controlled Release, 2016, 243, pp.1-10. ⟨10.1016/j.jconrel.2016.09.019⟩
Journal of Controlled Release, Elsevier, 2016, 243, pp.1-10. ⟨10.1016/j.jconrel.2016.09.019⟩
Journal of Controlled Release, 2016, 243, pp.1-10. ⟨10.1016/j.jconrel.2016.09.019⟩
International audience; Detection of intracerebral targets with imaging probes is challenging due to the non-permissive nature of blood-brain barrier (BBB). The present work describes two novel single-domain antibodies (VHHs or nanobodies) that speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::062c700438fcb7cb21a9d02d891e5144
https://hal-pasteur.archives-ouvertes.fr/pasteur-01375692/document
https://hal-pasteur.archives-ouvertes.fr/pasteur-01375692/document
Publikováno v:
Psychopharmacology. 215:709-720
Normal or pathological ageing is characterized by working-memory dysfunction paired with a marked reduction in several neurotransmitters activity. The development of therapeutic strategy centered on the glutamatergic system known to bear a critical r