Zobrazeno 1 - 10
of 1 053
pro vyhledávání: '"Matthias V"'
Autor:
Nina Schöbi, Andrea Duppenthaler, Matthias Horn, Andreas Bartenstein, Kristina Keitel, Matthias V. Kopp, Philipp K. A. Agyeman, Christoph Aebi
Publikováno v:
Infectious Disease Reports, Vol 16, Iss 5, Pp 864-869 (2024)
A Europe-wide outbreak of invasive pediatric group A streptococcal infections (iGAS) began in fall 2022. Here, we report the evolution of GAS hospitalizations in children and adolescents during the second outbreak year in 2023–2024 at a tertiary ce
Externí odkaz:
https://doaj.org/article/d337172883404dd28c6f92e23037fabb
Autor:
Liam Hudson, Jeremy W. Mason, Matthias V. Westphal, Matthieu J. R. Richter, Jonathan R. Thielman, Bruce K. Hua, Christopher J. Gerry, Guoqin Xia, Heather L. Osswald, John M. Knapp, Zher Yin Tan, Praveen Kokkonda, Ben I. C. Tresco, Shuang Liu, Andrew G. Reidenbach, Katherine S. Lim, Jennifer Poirier, John Capece, Simone Bonazzi, Christian M. Gampe, Nichola J. Smith, James E. Bradner, Connor W. Coley, Paul A. Clemons, Bruno Melillo, C. Suk-Yee Hon, Johannes Ottl, Christoph E. Dumelin, Jonas V. Schaefer, Ann Marie E. Faust, Frédéric Berst, Stuart L. Schreiber, Frédéric J. Zécri, Karin Briner
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Diversity-oriented synthesis (DOS) is a powerful strategy to prepare molecules with underrepresented features in commercial screening collections, resulting in the elucidation of novel biological mechanisms. In parallel to the development of
Externí odkaz:
https://doaj.org/article/36c9d05209eb47b1b03cc9fce00df87d
Autor:
Liam Hudson, Jeremy W. Mason, Matthias V. Westphal, Matthieu J. R. Richter, Jonathan R. Thielman, Bruce K. Hua, Christopher J. Gerry, Guoqin Xia, Heather L. Osswald, John M. Knapp, Zher Yin Tan, Praveen Kokkonda, Ben I. C. Tresco, Shuang Liu, Andrew G. Reidenbach, Katherine S. Lim, Jennifer Poirier, John Capece, Simone Bonazzi, Christian M. Gampe, Nichola J. Smith, James E. Bradner, Connor W. Coley, Paul A. Clemons, Bruno Melillo, C. Suk-Yee Hon, Johannes Ottl, Christoph E. Dumelin, Jonas V. Schaefer, Ann Marie E. Faust, Frédéric Berst, Stuart L. Schreiber, Frédéric J. Zécri, Karin Briner
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/d2f9e92baa034e31a3064fe3179e5c22
Autor:
Eva Steinke, Olaf Sommerburg, Simon Y. Graeber, Cornelia Joachim, Christiane Labitzke, Gyde Nissen, Isabell Ricklefs, Isa Rudolf, Matthias V. Kopp, Anna-Maria Dittrich, Marcus A. Mall, Mirjam Stahl
Publikováno v:
Frontiers in Medicine, Vol 9 (2023)
BackgroundLung disease as major cause for morbidity in patients with cystic fibrosis (CF) starts early in life. Its large phenotypic heterogeneity is partially explained by the genotype but other contributing factors are not well delineated. The clos
Externí odkaz:
https://doaj.org/article/0025cdeb020e4c1d8071eb3fe20056a3
Autor:
Solveig Lemmel, Markus Weckmann, Anna Wohlers, Adan Chari Jirmo, Ruth Grychtol, Isabell Ricklefs, Gyde Nissen, Anna Bachmann, Shantanu Singh, Juan Caicedo, Thomas Bahmer, Gesine Hansen, Erika Von Mutius, Klaus F. Rabe, Oliver Fuchs, Anna-Maria Dittrich, Bianca Schaub, Christine Happle, Anne E. Carpenter, Matthias Volkmar Kopp, Tim Becker, the ALLIANCE Study Group as part of the German Centre for Lung Research (DZL), Mustafa Abdo, Miguel Alcazar, Mira Berbig, Heike Biller, Xenia Bovermann, Folke Brinkmann, Mifflin-Rae Calveron, David S. DeLuca, Gesa Diekmann, Christian Dopfer, Markus Ege, Svenja Foth, Svenja Gaedcke, Karoline I. Gaede, Anika Habener, Christian Herzmann, Alexander Hose, Sabina Illi, Anne-Marie Kirsten, Naschla Kohistani-Greif, Inke R. König, Silke Van Koningsbruggen-Rietschel, Matthias V. Kopp, Johanna Kurz, Katja Landgraf-Rauf, Kristina Laubhahn, Lena Liboschik, Claudia Liebl, Berrit Liselotte Husstedt, Bin Liu, Nicole Maison, Aydin Malik, Carola Marzi, Meike Meyer, Catharina Nitsche, Frauke Pedersen, Mareike Price, Harald Renz, Ernst Rietschel, Barbara Roesler, Christina Schauberger, Tom Schildberg, Carsten Schmidt-Weber, Nicolaus Schwerk, Chrysanthi Skevaki, Alena Steinmetz, Laila Sultansei, Marlen Szewczyk, Dominik Thiele, Vera Veith, Gesche Voigt, Benjamin Waschki, Henrik Watz, Stefanie Weber, Nils Welchering, Esther Zeitlmann, Ulrich Zissler
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: Different asthma phenotypes are driven by molecular endotypes. A Th1-high phenotype is linked to severe, therapy-refractory asthma, subclinical infections and neutrophil inflammation. Previously, we found neutrophil granulocytes (NGs) fro
Externí odkaz:
https://doaj.org/article/fc7e3e168608484cb6c82625730f72c5
Autor:
Nicole Maison, Heidrun Herbrüggen, Bianca Schaub, Christina Schauberger, Svenja Foth, Ruth Grychtol, Mustafa Abdo, Henrik Watz, Wilfried Nikolaizik, Klaus F. Rabe, Matthias V. Kopp, Gesine Hansen, Erika von Mutius, Thomas Bahmer, Jimmy Omony, the ALLIANCE study group
Publikováno v:
Allergy, Asthma & Clinical Immunology, Vol 17, Iss 1, Pp 1-5 (2021)
Abstract Background There is currently a dramatic increase in the number of COVID-19 cases worldwide, and further drastic restrictions in our daily life will be necessary to contain this pandemic. The implications of restrictive measures like social-
Externí odkaz:
https://doaj.org/article/cdaa6a34031047c8859b7298e45b6b25
Autor:
Milenko Rakic, Manon Jaboyedoff, Sara Bachmann, Christoph Berger, Manuel Diezi, Philipp do Canto, Christopher B. Forrest, Urs Frey, Oliver Fuchs, Alain Gervaix, Amalia Stefani Gluecksberg, Michael Grotzer, Ulrich Heininger, Christian R. Kahlert, Daniela Kaiser, Matthias V. Kopp, Roger Lauener, Thomas J. Neuhaus, Paolo Paioni, Klara Posfay-Barbe, Gian Paolo Ramelli, Umberto Simeoni, Giacomo Simonetti, Christiane Sokollik, Ben D. Spycher, Claudia E. Kuehni
Publikováno v:
BMC Proceedings, Vol 15, Iss S13, Pp 1-15 (2021)
Abstract Background and purpose Continuous improvement of health and healthcare system is hampered by inefficient processes of generating new evidence, particularly in the case of rare diseases and paediatrics. Currently, most evidence is generated t
Externí odkaz:
https://doaj.org/article/1c527022e33744788b05b7da52c45936
Autor:
Samuel Ruiz de Martín Esteban, Irene Benito-Cuesta, Itziar Terradillos, Ana M. Martínez-Relimpio, M. Andrea Arnanz, Gonzalo Ruiz-Pérez, Claudia Korn, Catarina Raposo, Roman C. Sarott, Matthias V. Westphal, Izaskun Elezgarai, Erick M. Carreira, Cecilia J. Hillard, Uwe Grether, Pedro Grandes, M. Teresa Grande, Julián Romero
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The distribution and roles of the cannabinoid CB2 receptor in the CNS are still a matter of debate. Recent data suggest that, in addition to its presence in microglial cells, the CB2 receptor may be also expressed at low levels, yet biologically rele
Externí odkaz:
https://doaj.org/article/971c3ccb7b28416a96223192611a4cd6
Autor:
Mustafa Abdo, Henrik Watz, Vera Veith, Anne-Marie Kirsten, Heike Biller, Frauke Pedersen, Erika von Mutius, Matthias V. Kopp, Gesine Hansen, Benjamin Waschki, Klaus F. Rabe, Frederik Trinkmann, Thomas Bahmer
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-7 (2020)
Abstract Background Anti-T2 biological therapies have proven to effectively reduce acute exacerbations and daily doses of oral steroids in severe eosinophilic asthma. Despite the remarkable clinical efficacy, there are usually only moderate improveme
Externí odkaz:
https://doaj.org/article/d2e17f734af64ca8bc8c2ee40bb4edf3
Autor:
Manon Jaboyedoff, Milenko Rakic, Sara Bachmann, Christoph Berger, Manuel Diezi, Oliver Fuchs, Urs Frey, Alain Gervaix, Amalia Stefani Glücksberg, Michael Grotzer, Ulrich Heininger, Christian R. Kahlert, Daniela Kaiser, Matthias V. Kopp, Roger Lauener, Thomas J. Neuhaus, Paolo Paioni, Klara Posfay-Barbe, Gian Paolo Ramelli, Umberto Simeoni, Giacomo Simonetti, Christiane Sokollik, Ben D. Spycher, Claudia E. Kuehni
Publikováno v:
Swiss Medical Weekly, Vol 151, Iss 5152 (2021)
BACKGROUND: Improvement of paediatric healthcare is hampered by inefficient processes for generating new evidence. Clinical research often requires extra encounters with patients, is costly, takes place in an artificial situation with a biased select
Externí odkaz:
https://doaj.org/article/62129f6c6c4846ab90df6d6ae4231af5