Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Matthias U, Kassack"'
Autor:
Katja Schiedlauske, Alina Deipenbrock, Marc Pflieger, Alexandra Hamacher, Jan Hänsel, Matthias U. Kassack, Thomas Kurz, Nicole E. Teusch
Publikováno v:
Pharmaceuticals, Vol 17, Iss 6, p 752 (2024)
Pancreatic ductal adenocarcinoma (PDAC) is the most lethal form of pancreatic cancer characterized by therapy resistance and early metastasis, resulting in a low survival rate. Histone deacetylase (HDAC) inhibitors showed potential for the treatment
Externí odkaz:
https://doaj.org/article/88ca8e958d2e4fe59194bf10c332d5b1
Autor:
Aline Kaletsch, Maria Pinkerneil, Michèle J. Hoffmann, Ananda A. Jaguva Vasudevan, Chenyin Wang, Finn K. Hansen, Constanze Wiek, Helmut Hanenberg, Christoph Gertzen, Holger Gohlke, Matthias U. Kassack, Thomas Kurz, Wolfgang A. Schulz, Günter Niegisch
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-18 (2018)
Abstract Background Histone deacetylase inhibitors (HDACi) are promising anti-cancer drugs that could also be employed for urothelial carcinoma (UC) therapy. It is unclear, however, whether inhibition of all 11 zinc-dependent HDACs or of individual e
Externí odkaz:
https://doaj.org/article/e87d19bc77ef4eaa9cb7bb52c1e09692
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-13 (2017)
Abstract Background Widely established targeted therapies directed at triple negative breast cancer (TNBC) are missing. Classical chemotherapy remains the systemic treatment option. Cisplatin has been tested in TNBC but bears the disadvantage of resi
Externí odkaz:
https://doaj.org/article/bf4c7dea0a084108a9aef96fd9f60cf9
Autor:
Kim-Thao Le, Jan J. Bandolik, Matthias U. Kassack, Kenneth R. Wood, Claudia Paetzold, Marc S. Appelhans, Claus M. Passreiter
Publikováno v:
Molecules, Vol 26, Iss 3, p 688 (2021)
The dichloromethane extract from leaves of Melicope barbigera (Rutaceae), endemic to the Hawaiian island of Kaua’i, yielded four new and three previously known acetophenones and 2H-chromenes, all found for the first time in M. barbigera. The struct
Externí odkaz:
https://doaj.org/article/250e1ad5e6cd40e4bb0ff5a185468e5b
Autor:
Ki-Back Chu, Hae-Ahm Lee, Marc Pflieger, Fabian Fischer, Yodita Asfaha, Leandro A. Alves Avelar, Alexander Skerhut, Matthias U. Kassack, Finn K Hansen, Andrea Schöler, Thomas Kurz, Min-Jeong Kim, Eun-Kyung Moon, Fu-Shi Quan
Publikováno v:
ACS Infectious Diseases. 8:271-279
Autor:
Hans-Dieter Royer, Carsten Denkert, Brigitte Royer-Pokora, Manfred Dietel, Manfred Beier, Jan Budczies, Matthias U. Kassack, Alexandra Hamacher, Inge Napierski, Sybille Wolf-Kümmeth, Georg von Jonquières, Anne Pölitz, Barbara Hildebrandt, Kati Servan, Niels Eckstein
Supplementary Materials and Methods, Tables 1-4, Figures 1-5 from Hyperactivation of the Insulin-like Growth Factor Receptor I Signaling Pathway Is an Essential Event for Cisplatin Resistance of Ovarian Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eebd652c5403ef4201ff35d78675274
https://doi.org/10.1158/0008-5472.22380036
https://doi.org/10.1158/0008-5472.22380036
Autor:
Hans-Dieter Royer, Carsten Denkert, Brigitte Royer-Pokora, Manfred Dietel, Manfred Beier, Jan Budczies, Matthias U. Kassack, Alexandra Hamacher, Inge Napierski, Sybille Wolf-Kümmeth, Georg von Jonquières, Anne Pölitz, Barbara Hildebrandt, Kati Servan, Niels Eckstein
Platinum plays a central role in the therapy of ovarian cancer, and the emergence of platinum resistance is a major obstacle for clinical management of the disease. We treated A2780 ovarian cancer cells by weekly cycles of cisplatin over a period of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd194349894177406e13d95c1d31a870
https://doi.org/10.1158/0008-5472.c.6499425.v1
https://doi.org/10.1158/0008-5472.c.6499425.v1
Autor:
Marian Frank, Ferhat Can Özkaya, Werner E. G. Müller, Alexandra Hamacher, Matthias U. Kassack, Wenhan Lin, Zhen Liu, Peter Proksch
Publikováno v:
Marine Drugs, Vol 17, Iss 2, p 99 (2019)
The fungus Aspergillus ochraceus was isolated from the Mediterranean sponge Agelas oroides. The initial fermentation of the fungus on solid rice medium yielded 16 known compounds (4⁻19). The addition of several inorganic salts to the rice medium ma
Externí odkaz:
https://doaj.org/article/810c90fd7744452f914b5260d4c07a0b
Autor:
Andrea Schöler, Thomas Kurz, Sanil Bhatia, Jing Yang, Nadine Horstick-Muche, Finn K. Hansen, Alexandra Hamacher, Melf Sönnichsen, Arndt Borkhardt, Marc Pflieger, Matthias U. Kassack, Julian Schliehe-Diecks
Publikováno v:
Chemmedchem
The acetylome is important for maintaining the homeostasis of cells. Abnormal changes can result in the pathogenesis of immunological or neurological diseases, and degeneration can promote the manifestation of cancer. In particular, pharmacological i
Autor:
Matthias U. Kassack, Leandro A. Alves-Avelar, Thomas Kurz, Stefan Klinken, Beate Lungerich, Nadine Horstick-Muche, Yodita Asfaha, Alexander Jan Skerhut
Publikováno v:
Arkivoc. 2020:228-241