Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Matthias Truss"'
Autor:
Thomas Dahlet, Matthias Truss, Ute Frede, Hala Al Adhami, Anaïs F. Bardet, Michael Dumas, Judith Vallet, Johana Chicher, Philippe Hammann, Sarah Kottnik, Peter Hansen, Uschi Luz, Gonzalo Alvarez, Ghislain Auclair, Jochen Hecht, Peter N. Robinson, Christian Hagemeier, Michael Weber
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
DNA methylation targets CpG island promoters of germline genes to repress their expression in mouse somatic cells. Here the authors show that a transcription factor E2F6 is required to target CpG island DNA methylation and epigenetic silencing to ger
Externí odkaz:
https://doaj.org/article/f118f417497a4386a18456d4d7889a0a
Autor:
Subhash Thalappilly, Xiaolan Feng, Svitlana Pastyryeva, Keiko Suzuki, Daniel Muruve, Daniel Larocque, Stephane Richard, Matthias Truss, Andreas von Deimling, Karl Riabowol, Gesche Tallen
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21065 (2011)
The INhibitor of Growth tumor suppressors (ING1-ING5) affect aging, apoptosis, DNA repair and tumorigenesis. Plant homeodomains (PHD) of ING proteins bind histones in a methylation-sensitive manner to regulate chromatin structure. ING1 and ING2 conta
Externí odkaz:
https://doaj.org/article/baefd552e8bd44b695133d17022979a2
Autor:
Philippe Hammann, Hala Al Adhami, Gonzalo Alvarez, Matthias Truss, Sarah Kottnik, Christian Hagemeier, Johana Chicher, Judith Vallet, Anaïs F. Bardet, Jochen Hecht, Ute Frede, Thomas Dahlet, Michael Weber, Michael Dumas, Uschi Luz, Ghislain Auclair, Peter Hansen, Peter N. Robinson
Publikováno v:
Nature Communications
Nature Communications, 2021, 12, pp.3582. ⟨10.1038/s41467-021-23596-w⟩
Nature Communications, Nature Publishing Group, 2021, 12, pp.3582. ⟨10.1038/s41467-021-23596-w⟩
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications, 2021, 12, pp.3582. ⟨10.1038/s41467-021-23596-w⟩
Nature Communications, Nature Publishing Group, 2021, 12, pp.3582. ⟨10.1038/s41467-021-23596-w⟩
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
In mouse development, long-term silencing by CpG island DNA methylation is specifically targeted to germline genes; however, the molecular mechanisms of this specificity remain unclear. Here, we demonstrate that the transcription factor E2F6, a membe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7ab6abc4ce0075028f98d18c18beb4e
https://hal.science/hal-03380281/file/Dahlet_NatComm_2021.pdf
https://hal.science/hal-03380281/file/Dahlet_NatComm_2021.pdf
Autor:
Daniel M. Ibrahim, Jochen Hecht, Peter Hansen, Peter N. Robinson, Alexander Krannich, Matthias Truss
Publikováno v:
Genome Research. 25:1391-1400
Chromatin immunoprecipitation coupled with next-generation sequencing (ChIP-seq) is a powerful technology to identify the genome-wide locations of transcription factors and other DNA binding proteins. Computational ChIP-seq peak calling infers the lo
Autor:
Toni Pfaffeneder, Thomas Carell, Benjamin Hackner, Christian Hagemeier, Markus Müller, Stefan Schiesser, Matthias Truss
Publikováno v:
Angewandte Chemie. 124:6622-6626
Autor:
Christian Hagemeier, Markus Müller, Thomas Carell, Benjamin Hackner, Christian A. Deiml, Martin Münzel, Toni Pfaffeneder, Matthias Truß
Publikováno v:
Angewandte Chemie International Edition. 50:7008-7012
Cellular development requires the silencing and activation of specific gene sequences in a well-orchestrated fashion. Transcriptional gene silencing is associated with the clustered methylation of cytosine bases (C) in CpG units of promoters. The met
Autor:
Karl Seeger, Andrea Zelmer, Luigi Tornillo, Elisabeth Bruder, Christoph Bührer, Matthias Truss, Sven Wellmann
Publikováno v:
Pediatric Research. 67:35-41
Hypoxia and other adverse conditions are commonly encountered by rapidly growing cells. The RNA-binding protein RBM3 (RNA-binding motif protein 3), which is transcriptionally induced by low temperature and hypoxia, has recently been implicated in sur
Autor:
Christian Hagemeier, Sonja Krabbe, Brigitte Sinn, Ulrike Lass, Frank Kunitz, Matthias Truss, Ute Gesche Tallen, Sven Wellmann, Nikola Holtkamp, Guenter Henze, Brad M. Unryn, Reinhard Wurm, Andreas von Deimling, Karl Riabowol
Publikováno v:
Journal of Neuro-Oncology. 86:23-30
Impaired tumor suppressor functions, such as deficient p53, are characteristic for glioblastoma multiforme (GBM) and can cause resistance to DNA-damaging agents like cisplatin. We have recently shown that the INhibitor of Growth 1 (ING1) tumor suppre
Autor:
Michael Hummel, Christian Hagemeier, Ralf C. Bargou, Stephan Mathas, Matthias Truss, Brigitte Wollert-Wulf, Korinna Jöhrens, Martin Janz, Harald Stein, Kurt Bommert, Bernd Dörken
Publikováno v:
Blood. 107:2536-2539
Hodgkin/Reed-Sternberg (HRS) cells of classical Hodgkin lymphoma (cHL) display unique characteristics that discriminate cHL from other B-cell lymphomas and normal B cells. Therefore, comparative gene expression profiling of Hodgkin and non-Hodgkin B
Autor:
Christian Hagemeier, Axel Scholz, Ralf-Jürgen Kuban, Carmen Birchmeier, Michael Pohlers, Bettina Hoffmann, Matthias Truss, Markus Morkel, Michael Strehle, Ute Frede
Publikováno v:
Current Biology. 15:1051-1057
E2F transcription factors play a pivotal role in the regulation of cellular proliferation and can be subdivided into activating and repressing family members [1]. Like other E2Fs, E2F6 binds to E2F consensus sites, but in contrast to E2F1-5, it lacks