Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Matthias Spindler"'
Autor:
Wolfram Machann, Meinrad Beer, Michael Horn, Oliver M. Geier, Matthias Spindler, Herbert Köstler, Andreas Max Weng, Dietbert Hahn, Jan Ruff
Publikováno v:
Concepts in Magnetic Resonance Part A. 42:187-195
The aim of this study was to demonstrate that acquisition-weighted 31P magnetic resonance spectroscopy with spatial saturation allows for generation of metabolite maps showing the distribution of 31P metabolites, such as phosphocreatine (PCr) and ade
Autor:
Peter Nordbeck, Matthias Nahrendorf, Matthias Spindler, Joerg Ulrich Streif, Karl-Heinz Hiller, Stefan Neubauer, Kai Hu, David E. Sosnovik, Georg Ertl, Oliver Ritter, Wolfgang R. Bauer, Lisa Bauer, Peter M. Jakob
A decrease in the supply of ATP from the creatine kinase (CK) system is thought to contribute to the evolution of heart failure. However, previous studies on mice with a combined knockout of the mitochondrial and cytosolic CK (CK−/−) have not rev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57d96fcea8033473d80a8ae8c8c88c09
https://ora.ox.ac.uk/objects/uuid:f8074354-2065-42e9-bb9c-bf7ffd1ebb97
https://ora.ox.ac.uk/objects/uuid:f8074354-2065-42e9-bb9c-bf7ffd1ebb97
Autor:
Oliver Ritter, Matthias Nahrendorf, Julie Wallis, Stefan Neubauer, Peter Nordbeck, Karl-Heinz Hiller, Kai Hu, Matthias Spindler, Georg Ertl, Thomas Quaschning, Lisa Bauer, Wolfgang R. Bauer
OBJECTIVE: Creatine kinase (CK) is responsible for the transport of high-energy phosphates in excitable tissue and is of central importance in myocardial energy homeostasis. Significant changes in myocardial energetics have been reported in mice lack
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58e0b7b397f87ddeedb673a92ba8ac8d
https://doi.org/10.1016/j.cardiores.2004.10.006
https://doi.org/10.1016/j.cardiores.2004.10.006
Autor:
Song Zhang, Matthias Spindler, Kirsten Hoyer, Emirhan Nemutlu, Rong Tian, Petras P. Dzeja, Joanne S. Ingwall
Publikováno v:
The Journal of Physiology. 589:5193-5211
Non-Technical Summary Continuous and vigorous heart work is powered by the energetic grid consisting of mitochondria, miniature ATP-generating fuel cells, and molecular connecting circuits transferring and distributing high-energy phosphoryls. The cr
Autor:
Matthias Spindler, Alexander Crössmann, Sabine Bär, Paul Pauli, Wolfram Voelker, Regina Borst
Publikováno v:
Verhaltenstherapie. 17:46-51
Cardiac catheterizations are used to diagnose and, if necessary, treat stenoses of the heart vessels. However, many patients fear this procedure. The present study has evaluated a specially produced educational film on cardiac catheterization. Patien
Autor:
Timothy P. Ryan, Joanne S. Ingwall, Najia Jin, Robert M. Gill, Laura J. Bloem, Matthias Spindler, Marnie A. Higgins, Weiqun Shen
Publikováno v:
Journal of Molecular and Cellular Cardiology. 39:537-544
Decreases in total creatine kinase (CK) activity and creatine [Cr] combine to limit the capacity of the failing heart to rapidly re-synthesize ATP (energy reserve). If the loss in energy reserve could be reversed, cardiac contractile reserve may be i
Autor:
Haiko Remmert, Herbert Köstler, Matthias Spindler, Meinrad Beer, Stephanie Beer, Joern J.W. Sandstede, Dietbert Hahn
Publikováno v:
Journal of Magnetic Resonance Imaging. 20:798-802
Purpose To determine whether the recently applied technique of acquisition-weighted 31P-MR spectroscopy (AW-MRS) allows for the detection of depressed energy metabolism in patients with inferior wall myocardial infarctions. Materials and Methods Eigh
Autor:
Klaus Meyer, Ernest A. Boehm, Helga Wagner, Stefan Neubauer, Matthias Spindler, Hinrik Strömer, Andrea Leupold
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 287:H1039-H1045
The creatine kinase (CK) system is involved in the rapid transport of high-energy phosphates from the mitochondria to the sites of maximal energy requirements such as myofibrils and sarcolemmal ion pumps. Hearts of mice with a combined knockout of cy
Autor:
Stefan Engelhardt, Matthias Spindler, Martin J. Lohse, Helga Wagner, Stefan Neubauer, Reinhard Niebler, Lutz Hein
Publikováno v:
Journal of Molecular and Cellular Cardiology. 35:389-397
The beta-adrenergic receptor system not only plays a central role in modulating heart rate and left-ventricular (LV) contractility, but is also involved in the development of heart failure. We have, recently, shown that heart-specific overexpression
Publikováno v:
Journal of Biological Chemistry. 275:19742-19746
Creatine kinase (CK) exists as a family of isoenzymes in excitable tissue. We studied isolated perfused hearts from mice lacking genes for either the main muscle isoform of CK (M-CK) or both M-CK and the main mitochondrial isoform (Mt-CK) to determin