Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Matthias Schauen"'
Autor:
Matthias Schauen, Vladimir Y. Ganitkevich, J. Beuth, Nadine Lottmann, Katharina Maniura-Weber, Bistra Galunska, Jürgen H. Fischer, Tuan Anh Duong Dinh, Rudolf J. Wiesner, Sabrina Eckertz, Frank Stassen, Jan-Matthias Braun, Jürgen-Christoph von Kleist-Retzow, Hue-Tran Hornig-Do, Maria Bust, Klaus Wielckens, Wolfgang Hein
Publikováno v:
Experimental Cell Research. 313:3076-3089
Energy-producing pathways, adenine nucleotide levels, oxidative stress response and Ca(2+) homeostasis were investigated in cybrid cells incorporating two pathogenic mitochondrial DNA point mutations, 3243A>G and 3302A>G in tRNA(Leu(UUR)), as well as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e67546ba76bb8588ec7b80842366c5a
https://doi.org/10.1016/j.yexcr.2007.04.015
https://doi.org/10.1016/j.yexcr.2007.04.015
Autor:
Katrin Lanz, Hue-Tran Hornig-Do, Jürgen-Christoph von Kleist-Retzow, Rudolf J. Wiesner, Matthias Schauen, Alexei P. Kudin, Wolfram S. Kunz, Claudia Wickenhauser
Publikováno v:
Journal of Investigative Dermatology. 127:1084-1093
The energy metabolism of the epidermis has been the subject of controversy; thus we characterized the mitochondrial phenotype of human primary keratinocytes and fibroblasts, in cell culture and in human skin sections. We found that keratinocytes resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6cb0a9efd6e38193a93ad69a21869f9
https://doi.org/10.1038/sj.jid.5700666
https://doi.org/10.1038/sj.jid.5700666
Publikováno v:
Free Radical Biology and Medicine. 42:499-509
Ultraviolet A (UVA), the long wavelength part of the sun's ultraviolet radiation, elicits its harmful effects through production of reactive oxygen species. In this study, we have tested the hypothesis that the mitochondrial electron transport chain,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73010138e0c67e9df5ba801c32407f30
https://doi.org/10.1016/j.freeradbiomed.2006.11.016
https://doi.org/10.1016/j.freeradbiomed.2006.11.016
Autor:
Katharina Maniura-Weber, Myriam Möllers, Jürgen-Christoph von Kleist-Retzow, Robert N. Lightowlers, Laurence A. Bindoff, Rudolf J. Wiesner, Mark Helm, Armine Hayrapetyan, Katrin Engemann, Sabrina Eckertz, Matthias Schauen
Publikováno v:
Nucleic Acids Research
The gene encoding mt-tRNALeu(UUR), MT-TL1, is a hotspot for pathogenic mtDNA mutations. Amongst the first to be described was the 3302A>G transition which resulted in a substantial accumulation in patient muscle of RNA19, an unprocessed RNA intermedi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db0f8ff250b1141dcf26254d97af9a79
https://doi.org/10.1093/nar/gkl727
https://doi.org/10.1093/nar/gkl727
Autor:
Judita Makuc, Margarida Casal, Matthias Schauen, Bruno André, Sandra Paiva, Eckhard Boles, Cecília Leão, Reinhard Krämer
Publikováno v:
Yeast. 18:1131-1143
We have characterized the monocarboxylate permease family of Saccharomyces cerevisiae comprising five proteins. We could not find any evidence that the monocarboxylate transporter-homologous (Mch) proteins of S. cerevisiae are involved in the uptake
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80b34ae5d0de777e9b74654070676d74
https://doi.org/10.1002/yea.763
https://doi.org/10.1002/yea.763
Autor:
Carsten Merkwirth, Rudolf J. Wiesner, Alexander Müller, Matthias Schauen, Ralf Paus, Daniela Weiland, Desmond J. Tobin, Thomas Krieg, Thomas Langer, Anna Wille, Nils-Göran Larsson, Olivier R. Baris, Anke Klose, Jennifer E. Kloepper, Johannes F.G. Neuhaus
Publikováno v:
Stem cells (Dayton, Ohio). 29(9)
Tissue stem cells and germ line or embryonic stem cells were shown to have reduced oxidative metabolism, which was proposed to be an adaptive mechanism to reduce damage accumulation caused by reactive oxygen species. However, an alternate explanation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2064dbea870e1cbc8aad30126151712f
https://pubmed.ncbi.nlm.nih.gov/21780252
https://pubmed.ncbi.nlm.nih.gov/21780252
Publikováno v:
BIOspektrum. 19:59-60
Mammalian mtDNA is packaged in DNA-protein complexes denoted mito-chondrial nucleoids. A combination of super-resolution STED microscopy and molecular biology was used to study mitochondrial nucleoids in mammalian cells. Mitochondrial nucleoids have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc9927053c88d7713f6cfe8f81813e80
https://doi.org/10.1007/s12268-013-0273-5
https://doi.org/10.1007/s12268-013-0273-5
Autor:
Thomas Simmet, Peter Brenneisen, Christina Hinrichs, Karin Scharffetter-Kochanek, Silke Sulyok, Matthias Schauen, Meinhard Wlaschek, Maurizio Podda, Lars-A. Schneider, Thomas Krieg, Tatjana Syrovets, Jutta Wenk, Andrea Sabiwalsky, Thorsten Peters, Thomas Wirth, Joachim Dissemond, Ninel Azoitei, Jutta Schüller
Publikováno v:
The Journal of biological chemistry. 279(44)
Phospholipid-hydroperoxide glutathione peroxidase (PHGPx) exhibits high specific activity in reducing phosphatidylcholine hydroperoxides (PCOOHs) and thus may play a central role in protecting the skin against UV irradiation-triggered detrimental lon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a2c506d97dc15b02effe843e62d5406
https://pubmed.ncbi.nlm.nih.gov/15308634
https://pubmed.ncbi.nlm.nih.gov/15308634
Autor:
Jutta Wenk, Meinhard Wlaschek, Peter Brenneisen, R. Blaudschun, Matthias Schauen, Karin Scharffetter-Kochanek
Publikováno v:
Fundamentals for the Assessment of Risks from Environmental Radiation ISBN: 9780792356684
The increase in UV irradiation on earth due to the stratospheric ozone depletion represents a major environmental threat to the skin increasing its risk of photooxidative damage by reactive oxygen species (ROS). ROS have been implicated in several ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aea00edbf7e30b5bb8d964dcd1f91ec7
https://doi.org/10.1007/978-94-011-4585-5_45
https://doi.org/10.1007/978-94-011-4585-5_45
Autor:
Karin Scharffetter-Kochanek, Jutta Wenk, Matthias Schauen, Peter Brenneisen, Christina Hommel, Meinhard Wlaschek
Publikováno v:
Journal of Dermatological Science. 16:S17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7dc630d8d58fe4da083c58ed7f5233d1
https://doi.org/10.1016/s0923-1811(98)83098-3
https://doi.org/10.1016/s0923-1811(98)83098-3