Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Matthias Rothermundt"'
Autor:
Emanuel Schwarz, Rauf Izmailov, Michael Spain, Anthony Barnes, James P. Mapes, Paul C. Guest, Hassan Rahmoune, Sandra Pietsch, F. Markus Leweke, Matthias Rothermundt, Johann Steiner, Dagmar Koethe, Laura Kranaster, Patricia Ohrmann, Thomas Suslow, Yishai Levin, Bernhard Bogerts, Nico (JM) van Beveren, George McAllister, Natalya Weber, David Niebuhr, David Cowan, Robert H. Yolken, Sabine Bahn
Publikováno v:
Biomarker Insights, Vol 2010, Iss 5, Pp 39-47 (2010)
We describe the validation of a serum-based test developed by Rules-Based Medicine which can be used to help confirm the diagnosis of schizophrenia. In preliminary studies using multiplex immunoassay profiling technology, we identified a disease sign
Externí odkaz:
https://doaj.org/article/e486a252115a4c4298b5b664fb3fe20a
Autor:
Jordan M Ramsey, Emanuel Schwarz, Paul C Guest, Nico J M van Beveren, F Markus Leweke, Matthias Rothermundt, Bernhard Bogerts, Johann Steiner, Sabine Bahn
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e78729 (2013)
BACKGROUND: In schizophrenia, sex specific dimorphisms related to age of onset, course of illness and response to antipsychotic treatment may be mirrored by sex-related differences in the underlying molecular pathways. METHODOLOGY/PRINCIPAL FINDINGS:
Externí odkaz:
https://doaj.org/article/62e7ee07617c4e26b021937e1c2f8c46
Autor:
Jordan M Ramsey, Emanuel Schwarz, Paul C Guest, Nico J M van Beveren, F Markus Leweke, Matthias Rothermundt, Bernhard Bogerts, Johann Steiner, Liliana Ruta, Simon Baron-Cohen, Sabine Bahn
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51504 (2012)
Sex is an important factor in the prevalence, incidence, progression, and response to treatment of many medical conditions, including autoimmune and cardiovascular diseases and psychiatric conditions. Identification of molecular differences between t
Externí odkaz:
https://doaj.org/article/5a148c9f0e184827a33de7b4847ab2b1
Autor:
Laura Grosse, Sabine Bahn, Matthias Rothermundt, Jason D. Cooper, Pawel Stocki, Volker Arolt, Man K. Chan, Tillmann Ruland
Publikováno v:
Psychopharmacology. 233:3051-3059
A substantial number of patients suffering from major depressive disorder (MDD) do not respond to multiple trials of anti-depressants, develop a chronic course of disease and become treatment resistant. Most of the studies investigating molecular cha
Autor:
Florian Kästner, Susanne Manhart, Leona Wagner, Jens-Ulrich Rahfeld, Jutta Schade, Nadine Frerker, Åsa Petersén, Matthias Rothermundt, Dagmar Schlenzig, Steffen Rossner, Raik Wolf, Blair R. Leavitt, Stephan von Hörsten, Ulrike Zeitschel, Daniel Gündel, Ulf-Torsten Gärtner, Hans-Ulrich Demuth
Publikováno v:
Journal of Neurochemistry. 135:1019-1037
The bioactivity of neuropeptide Y (NPY) is either N-terminally modulated with respect to receptor selectivity by dipeptidyl peptidase 4 (DP4)-like enzymes or proteolytic degraded by neprilysin or meprins, thereby abrogating signal transduction. Howev
Autor:
Björn Bluhm, Björn Laffer, Daniela Hirnet, Oliver Ambrée, Matthias Rothermundt, Christian Lohr
Publikováno v:
The Cerebellum. 14:119-127
The calcium-binding protein S100B has been shown to support neuron proliferation, migration and neurite growth in vitro, while the significance of S100B for neuronal development in vivo is controversial. We have investigated the effect of S100B defic
Autor:
Emanuel Schwarz, Viktoria Stelzhammer, Hassan Rahmoune, Carina Sondermann, Nikolaus Michael, Paul C. Guest, Sabine Bahn, Matthias Rothermundt
Publikováno v:
European Neuropsychopharmacology, 23(10), 1199-1207. Elsevier
Electroconvulsive therapy (ECT) is mainly used to treat medication resistant major depressive disorder (MOD) patients, with a remission rate of up to 90%. However, little is known about the serum molecular changes induced by this treatment. Understan
Autor:
Volker Arolt, Christa Hohoff, Jens Buschert, Rupert Palme, Chadi Touma, Weiqi Zhang, Oliver Ambrée, Matthias Rothermundt
Publikováno v:
Journal of Psychiatric Research; Vol 47
Genetic variants as well as increased serum levels of the neurotrophic factor S100B are associated with different psychiatric disorders. However, elevated S100B levels are also related to a better therapeutic outcome in psychiatric patients. The func
Autor:
Julian A. J. Jaros, Sabine Bahn, Daniel Martins-de-Souza, Hassan Rahmoune, Paul C. Guest, Matthias Rothermundt, F. Markus Leweke
Publikováno v:
Journal of Proteomics, 76, 43-55. Elsevier
Journal of Proteomics; Vol 76
Journal of Proteomics; Vol 76
Most proteomic studies to date have attempted to identify changes in protein levels without considering the effects of post-translational modifications (PTM). However, characteristic changes of PTM such as phosphorylation could be biologically inform
Autor:
Sabine Bahn, Hassan Ramoune, F. Markus Leweke, Daniel Martins-de-Souza, Julian A. J. Jaros, Matthias Rothermundt, Paul C. Guest
Publikováno v:
Journal of Proteomics, 76, 36-42. Elsevier
Journal of Proteomics; Vol 76
Journal of Proteomics; Vol 76
The process of protein phosphorylation in cells is well studied in the context of a wide range of biologic functions such as signalling, cell cycle, cell growth and differentiation, and others. In contrast, little progress has been made in the invest