Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Matthias Romauch"'
Autor:
Matthias Romauch
Publikováno v:
Open Biology, Vol 10, Iss 4 (2020)
Zinc-α2-glycoprotein (ZAG) is a major plasma protein whose levels increase in chronic energy-demanding diseases and thus serves as an important clinical biomarker in the diagnosis and prognosis of the development of cachexia. Current knowledge sugge
Externí odkaz:
https://doaj.org/article/b83c8b8e0b0d42cf9bf73a7478bfc81a
Autor:
Martina Schweiger, Matthias Romauch, Renate Schreiber, Gernot F. Grabner, Sabrina Hütter, Petra Kotzbeck, Pia Benedikt, Thomas O. Eichmann, Sohsuke Yamada, Oskar Knittelfelder, Clemens Diwoky, Carina Doler, Nicole Mayer, Werner De Cecco, Rolf Breinbauer, Robert Zimmermann, Rudolf Zechner
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
The enzyme Atgl participates in the breakdown of lipids in adipose tissue. Here the authors show that pharmacological inhibition of Atgl reduces weight gain and improves metabolic health in mice fed a high-fat diet, without causing adverse effects in
Externí odkaz:
https://doaj.org/article/6897b936ca4b4463ba1c491fe09495d6
Autor:
Manoja K. Brahma, Rene C. Adam, Nina M. Pollak, Doris Jaeger, Kathrin A. Zierler, Nadja Pöcher, Renate Schreiber, Matthias Romauch, Tarek Moustafa, Sandra Eder, Thomas Ruelicke, Karina Preiss-Landl, Achim Lass, Rudolf Zechner, Guenter Haemmerle
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 11, Pp 2229-2241 (2014)
Fibroblast growth factor 21 (FGF21) is a PPARα-regulated gene elucidated in the liver of PPARα-deficient mice or PPARα agonist-treated mice. Mice globally lacking adipose triglyceride lipase (ATGL) exhibit a marked defect in TG catabolism associat
Externí odkaz:
https://doaj.org/article/70b6f2e8c3c945ada93dc92191f4dc93
Autor:
Martina Schweiger, Matthias Romauch, Renate Schreiber, Gernot F Grabner, Sabrina Hütter, Petra Kotzbeck, Pia Benedikt, Thomas O Eichmann, Sohsuke Yamada, Oskar Knittelfelder, Clemens Diwoky, Carina Doler, Nicole Mayer, Werner De Cecco, Rolf Breinbauer, Robert Zimmermann, Rudolf Zechner
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-1 (2017)
Nature Communications 8: Article number: 14859 2017); Published: 22 March 2017; Updated: 25 April 2017 The affiliation details for R. Zimmermann, R. Zechner and R. Breinbauer are incorrect in this Article. The correct affiliation details for these au
Externí odkaz:
https://doaj.org/article/9abdbcbfe8384067984208bd52821dad
Autor:
Anna Katharina Migglautsch, Gernot F. Grabner, Rudolf Zechner, Carina Julia Doler, Nicole Mayer, Michaela Christina Melcher, Martina Schweiger, Rolf Breinbauer, Robert Zimmermann, Elisabeth Fuchs, Matthias Romauch
Publikováno v:
Bioorganicmedicinal chemistry. 28(16)
High serum fatty acid (FA) levels are causally linked to the development of insulin resistance, which eventually progresses to type 2 diabetes and non-alcoholic fatty liver disease (NAFLD) generalized in the term metabolic syndrome. Adipose triglycer
Autor:
Talal A. Sallam, Matthias Romauch
Publikováno v:
Open Biology, Vol 10, Iss 4 (2020)
Open Biology
Open Biology
Zinc-α2-glycoprotein (ZAG) is a major plasma protein whose levels increase in chronic energy-demanding diseases and thus serves as an important clinical biomarker in the diagnosis and prognosis of the development of cachexia. Current knowledge sugge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c3b7eff026509ac9bca7ec76a8cb433
https://doi.org/10.1101/727214
https://doi.org/10.1101/727214
Autor:
Maria A, Pribasnig, Irina, Mrak, Gernot F, Grabner, Ulrike, Taschler, Oskar, Knittelfelder, Barbara, Scherz, Thomas O, Eichmann, Christoph, Heier, Lukas, Grumet, Jakob, Kowaliuk, Matthias, Romauch, Stefan, Holler, Felix, Anderl, Heimo, Wolinski, Achim, Lass, Rolf, Breinbauer, Gunther, Marsche, J Mark, Brown, Robert, Zimmermann
Publikováno v:
The Journal of Biological Chemistry
Background: Bis(monoacylglycero)phosphate (BMP) plays a key role in the degradation and sorting of lipids in acidic organelles. Results: ABHD6 degrades BMP and co-localizes with late endosomes/lysosomes. Knockdown of ABHD6 increases hepatic BMP level
Autor:
Renate Schreiber, Nadja Pöcher, Rene C. Adam, Doris Jaeger, Achim Lass, Kathrin A. Zierler, Matthias Romauch, Karina Preiss-Landl, Guenter Haemmerle, Tarek Moustafa, Nina M. Pollak, Rudolf Zechner, Sandra Eder, Thomas Ruelicke, Manoja K. Brahma
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 11, Pp 2229-2241 (2014)
Fibroblast growth factor 21 (FGF21) is a PPARα-regulated gene elucidated in the liver of PPARα-deficient mice or PPARα agonist-treated mice. Mice globally lacking adipose triglyceride lipase (ATGL) exhibit a marked defect in TG catabolism associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf05a1a5baa8ae871f2aa2f2865ebe39
https://europepmc.org/articles/PMC4617126/
https://europepmc.org/articles/PMC4617126/
Autor:
Gerald Höfler, Thomas O. Eichmann, Irina Mrak, Christoph Heier, Jakov Ivkovic, Nicole Mayer, Robert Zimmermann, Gernot F. Grabner, Martina Schweiger, Rudolf Zechner, Rolf Breinbauer, Elisabeth Fuchs, Achim Lass, Christian Fledelius, Matthias Romauch
Publikováno v:
Nature chemical biology
Adipose triglyceride lipase (ATGL) is rate limiting in the mobilization of fatty acids from cellular triglyceride stores. This central role in lipolysis marks ATGL as an interesting pharmacological target as deregulated fatty acid metabolism is close
Autor:
Christopher Linington, Jan Bauer, Maria K. Storch, Matthias Romauch, Robert Weissert, Sonja Hochmeister, Thomas Seifert-Held, Franz Fazekas, H.-P. Hartung
Publikováno v:
Experimental neurology. 237(1)
The cell adhesion molecule N-cadherin is involved in several processes during central nervous system development, but also in certain pathologic conditions in the adult brain, including tumorigenesis and Alzheimer's disease. N-cadherin function in in