Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Matthias R. Schmidt"'
Autor:
Stephen J. Tucker, Matthias R. Schmidt, Markus Rapedius, Mark S.P. Sansom, Thomas Baukrowitz, Chetan Sharma, Phillip J. Stansfeld
Publikováno v:
Channels
We previously reported that TREK-1 gating by internal pH and pressure occurs close to or within the selectivity filter. These conclusions were based upon kinetic measurements of high-affinity block by quaternary ammonium (QA) ions that appeared to ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7b52c6042ba3d5d39ae0fc216f4b11a
https://ora.ox.ac.uk/objects/uuid:9f65f61e-1fe5-4f25-9974-bfac97e18d8f
https://ora.ox.ac.uk/objects/uuid:9f65f61e-1fe5-4f25-9974-bfac97e18d8f
Protein-lipid interactions regulate many membrane protein functions. Using a multiscale approach that combines coarse-grained and atomistic molecular dynamics simulations, we have predicted the binding site for the anionic phospholipid phosphatidylin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::847cc352ef9b63a36c680aea947a3ab1
https://ora.ox.ac.uk/objects/uuid:d34506a3-9b4e-4699-ae7a-5c4ae75b1d47
https://ora.ox.ac.uk/objects/uuid:d34506a3-9b4e-4699-ae7a-5c4ae75b1d47
Publikováno v:
Biophysical Journal. 104(2)
We are interested in understanding the mechanism of modulation of inwardly-rectifying (Kir) and two-pore (K2P) potassium ion channels by physiological and modulatory lipids. The phospholipid phosphatidylinositol 4,5-bisphosphate (PIP2) is critical fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9951aacb0289c4deb485500b06aa4205
Autor:
João R. C. Muniz, Rita De Zorzi, Vassiliy N. Bavro, Mark S.P. Sansom, Stephen J. Tucker, Catherine Vénien-Bryan, Matthias R. Schmidt, Lejla Zubcevic
Publikováno v:
Nature structural & molecular biology
KirBac channels are prokaryotic homologs of mammalian inwardly rectifying (Kir) potassium channels, and recent crystal structures of both Kir and KirBac channels have provided major insight into their unique structural architecture. However, all of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ce70759e0dcf62ad140c358133b8eb3
http://ora.ox.ac.uk/objects/uuid:692713ea-b523-44eb-b8e8-92d14e26ec25
http://ora.ox.ac.uk/objects/uuid:692713ea-b523-44eb-b8e8-92d14e26ec25
Autor:
Mark S.P. Sansom, Thomas Baukrowitz, Markus Rapedius, Stephen J. Tucker, Phillip J. Stansfeld, Matthias R. Schmidt
Publikováno v:
Biophysical Journal. 100:431a
Phosphatidylinositol bisphosphate (PIP2) is an activator of mammalian inwardly rectifying potassium (Kir) channels. We have used multiscale simulations, via a sequential combination of coarse-grained and atomistic molecular dynamics to explore the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa51493a447cfccd903b93de42e4be1b
https://doi.org/10.1016/j.bpj.2010.12.2547
https://doi.org/10.1016/j.bpj.2010.12.2547
Autor:
Vassiliy N. Bavro, Stephen J. Tucker, João R. C. Muniz, Matthias R. Schmidt, Rita De Zorzi, Mark S.P. Sansom, Lejla Zubcevic, Catherine Vénien-Bryan
Publikováno v:
ResearcherID
KirBac channels are prokaryotic homologs of mammalian inwardly-rectifying (Kir) potassium channels and recent X-ray crystal structures of both Kir and KirBac channels have provided a major insight into their unique structural architecture. However, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d17a4b02f624628494e36eeaec34c1f