Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Matthias Prager"'
Publikováno v:
Inflammatory Bowel Diseases. 22:2356-2368
BACKGROUND Smoking worsens Crohn's disease (CD). The aryl hydrocarbon receptor (AhR) is a transcription factor that mediates the toxicity of dioxinlike chemicals. We hypothesized that AHR variants and smoking influence CD. METHODS Exon-intron boundar
Publikováno v:
British Journal of Nutrition. 116:1061-1067
Malnutrition is a frequent feature in Crohn’s disease (CD), affects patient outcome and must be recognised. For chronic inflammatory diseases, recent guidelines recommend the development of combined malnutrition and inflammation risk scores. We aim
Publikováno v:
Journal of Digestive Diseases. 16:713-722
Objective Genome-wide association studies have identified single nucleotide polymorphisms in genes that might influence intestinal barrier function (HNF4A, ECM1, CDH1 and LAMB1) to increase the risk for ulcerative colitis (UC). The aim of our study w
Publikováno v:
International Journal of Colorectal Disease. 29:909-915
Variants modulating expression of the prostaglandin receptor 4 (PTGER4) have been reported to be associated with Cohn’s disease (CD), but the clinical impact remains to be elucidated. We analyzed these variants in a large German inflammatory bowel
Autor:
Robert Wentrup, Nicola Winkelmann, Andrey Mitroshkin, Matthias Prager, Winfried Voderholzer, Guido Schachschal, Christian J, null rgensen, Carsten B, null ning
Publikováno v:
Gut and Liver
Background/aims Standard treatments are not available for hilar nonresectable cholangiocarcinoma (NCC). It is unknown whether combination therapy of photodynamic therapy (PDT) plus systemic chemotherapy is superior to PDT alone. Methods We retrospect
Autor:
Sabine Buhner, Matthias Prager, Andreas Sturm, Daniel C. Baumgart, Herbert Lochs, Carsten Büning, Nora Geissler, Janine Büttner, Verena Haas
Publikováno v:
Inflammatory Bowel Diseases. 18:1932-1939
Background: A disturbed epithelial barrier could play a pivotal role in ulcerative colitis (UC). We performed a family-based study analyzing in vivo gastrointestinal permeability in patients with UC, their healthy relatives, spouses, and controls. Me
Autor:
Carsten Büning, Martin Zeitz, Matthias Prager, Daniel C. Baumgart, Verena Haas, Andreas Sturm, Janine Büttner
Publikováno v:
International Journal of Colorectal Disease. 27:565-573
The aetiology of intestinal barrier dysfunction in Crohn's disease (CD) is poorly understood. Associations in relatives of CD families suggest a genetic basis, but the relevant variants are still unknown. We hypothesized that variants in genes occurr
Publikováno v:
Journal of digestive diseases. 16(12)
Genome-wide association studies have identified single nucleotide polymorphisms in genes that might influence intestinal barrier function (HNF4A, ECM1, CDH1 and LAMB1) to increase the risk for ulcerative colitis (UC). The aim of our study was to dete
Autor:
Rainer Dietz, Bakytbek Imanov, Mirsaid M. Mirrakhimov, Karl Josef Osterziel, Nana Bit-Avragim, Bernard Hoffmann, Reinhard Geßner, Dinara A. Usupbaeva, Raisa I. Rudenko, Andreas Perrot, Zhyldyz Kabaeva, Hajo Schmidt-Traub, Michal Tendera, Matthias Prager, Anna Wycisk, Heiko Witt
Publikováno v:
Journal of Molecular Medicine. 83:468-477
Hypertrophic cardiomyopathy (HCM) is a frequent, autosomal-dominant cardiac disease and manifests predominantly as left ventricular hypertrophy. Mutations in the cardiac beta-myosin heavy chain gene (MYH7) are responsible for the disease in about 30%
Autor:
R. Balfour Sartor, Nicola Schaltenberg, Dirk Haller, Matthias Prager, Tilo Wuensch, Sina S Ullrich, Eva Rath, Peter Bugert, Hannelore Daniel, Mathias Chamaillard, Stephan Schulz, Ulf B. Goebel, Heiko Witt, Carsten Büning
Publikováno v:
Inflammatory bowel diseases. 20(4)
PEPT1 was proposed to be expressed only in inflamed colonic tissues in which it could contribute to inflammatory bowel disease (IBD) development by transporting bacterial peptides, such as muramyl dipeptide (MDP), that activate intracellular pattern