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pro vyhledávání: '"Matthias Plitzko"'
Publikováno v:
Principles and Practices of Lyophilization in Product Development and Manufacturing ISBN: 9783031126338
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8eb31da1482905dff034d5269610a5e
https://doi.org/10.1007/978-3-031-12634-5_14
https://doi.org/10.1007/978-3-031-12634-5_14
Autor:
Satoshi Ohtake, Bakul Bhatnagar, Luy Bernhard, Serguei Tchessalov, Matthias Plitzko, Alina Alexeenko, Israel B. Sebastião
Publikováno v:
Journal of Pharmaceutical Sciences. 108:2063-2074
In spray freeze-drying (SFD), the solution is typically dispersed into a gaseous cold environment producing frozen microparticles that are subsequently dried via sublimation. This technology can potentially manufacture bulk lyophilized drugs at highe
Autor:
Israel B. Sebastião, Alina Alexeenko, Luy Bernhard, Bakul Bhatnagar, Satoshi Ohtake, Serguei Tchessalov, Matthias Plitzko
Publikováno v:
Journal of Pharmaceutical Sciences. 108:2075-2085
Spray freeze-drying is an evolving technology that combines the benefits of spray-drying and conventional lyophilization techniques to produce drug substance and drug product as free-flowing powders. The high surface-to-volume ratio associated to the
Publikováno v:
Drying Technology. 24:711-719
The aim of this study is to develop the spray freeze drying process and its hardware and to investigate its capabilities to dry thermosensible substances such as pharma-proteins at normal and low pressures. As the result, the spray freeze fluidized