Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Matthias P.A. Ebert"'
Autor:
Sai Wang, Frederik Link, Mei Han, Roohi Chaudhary, Anastasia Asimakopoulos, Roman Liebe, Ye Yao, Seddik Hammad, Anne Dropmann, Marinela Krizanac, Claudia Rubie, Laura Kim Feiner, Matthias Glanemann, Matthias P.A. Ebert, Ralf Weiskirchen, Yoav I. Henis, Marcelo Ehrlich, Steven Dooley
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 4, Pp 567-587 (2024)
Background & Aims: Transforming growth factor-β1 (TGF-β1) plays important roles in chronic liver diseases, including metabolic dysfunction–associated steatotic liver disease (MASLD). MASLD involves various biological processes including dysfuncti
Externí odkaz:
https://doaj.org/article/07620ad4cf5e4b2ba329ca9744f25574
Autor:
Tobias Gutting, Veronika Hauber, Jens Pahl, Kay Klapproth, Wenyue Wu, Ioana Dobrota, Frank Herweck, Juliane Reichling, Laura Helm, Torsten Schroeder, Beifang Li, Philip Weidner, Tianzuo Zhan, Maximilian Eckardt, Johannes Betge, Sebastian Belle, Carsten Sticht, Timo Gaiser, Michael Boutros, Matthias P.A. Ebert, Adelheid Cerwenka, Elke Burgermeister
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Only a small subset of colorectal cancer (CRC) patients benefits from immunotherapies, comprising blocking antibodies (Abs) against checkpoint receptor “programmed-cell-death-1” (PD1) and its ligand (PD-L1), because most cases lack the required m
Externí odkaz:
https://doaj.org/article/76d82438b7e2457c9fd5fa68a566c022
Autor:
Isabel Hinsenkamp, Sandra Schulz, Mareike Roscher, Anne-Maria Suhr, Björn Meyer, Bogdan Munteanu, Jens Fuchser, Stefan O. Schoenberg, Matthias P.A. Ebert, Björn Wängler, Carsten Hopf, Elke Burgermeister
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 18, Iss 8, Pp 500-511 (2016)
Gastric cancer (GC) remains a malignant disease with high mortality. Patients are frequently diagnosed in advanced stages where survival prognosis is poor. Thus, there is high medical need to find novel drug targets and treatment strategies. Recently
Externí odkaz:
https://doaj.org/article/36ee678334954d4dbb182756943c6a8a
Autor:
Teresa Friedrich, Michaela Söhn, Tobias Gutting, Klaus-Peter Janssen, Hans-Michael Behrens, Christoph Röcken, Matthias P.A. Ebert, Elke Burgermeister
Publikováno v:
EBioMedicine, Vol 8, Iss C, Pp 159-172 (2016)
Full-length (FL) docking protein-1 (DOK1) is an adapter protein which inhibits growth factor and immune response pathways in normal tissues, but is frequently lost in human cancers. Small DOK1 variants remain in cells of solid tumors and leukemias, a
Externí odkaz:
https://doaj.org/article/63f31ab10b9d4a4b9d6b2609c245f16a
Autor:
Annette T. Byrne, Jochen H.M. Prehn, Livio Trusolino, Claudio Isella, Andrea Bertotti, Diether Lambrechts, Enzo Medico, Rodrigo Dienstmann, Josep Tabernero, Guillem Argilés, Patrick Dicker, Matthias P.A. Ebert, Johannes Betge, Luise Halang, Bram Boeckx, Elodie Modave, Evy Vanderheyden, Manuela Salvucci, Eugenia R. Zanella, Francesco Sassi, Andreas U. Lindner, Niraj Khemka, Giorgia Migliardi, Alice C. O'Farrell, Adam Lafferty
Purpose:Regorafenib (REG) is approved for the treatment of metastatic colorectal cancer, but has modest survival benefit and associated toxicities. Robust predictive/early response biomarkers to aid patient stratification are outstanding. We have exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b03cb7f23937564cd04f0a66b41f08cc
https://doi.org/10.1158/1078-0432.c.6530519
https://doi.org/10.1158/1078-0432.c.6530519
Autor:
Annette T. Byrne, Jochen H.M. Prehn, Livio Trusolino, Claudio Isella, Andrea Bertotti, Diether Lambrechts, Enzo Medico, Rodrigo Dienstmann, Josep Tabernero, Guillem Argilés, Patrick Dicker, Matthias P.A. Ebert, Johannes Betge, Luise Halang, Bram Boeckx, Elodie Modave, Evy Vanderheyden, Manuela Salvucci, Eugenia R. Zanella, Francesco Sassi, Andreas U. Lindner, Niraj Khemka, Giorgia Migliardi, Alice C. O'Farrell, Adam Lafferty
Supplementary Figures S1 - S8 and Table S1. Fig S1: Analysis of copy number burden in a PDX population trial of REG treated mCRC PDXs. Fig S2: Effect of REG on microvessel density and proliferation according to CNA cluster. Fig S3 - S6: BCL-2 family
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f28b84a3384bf08ad570848bf99f729
https://doi.org/10.1158/1078-0432.22480721
https://doi.org/10.1158/1078-0432.22480721
Autor:
Matthias P.A. Ebert, Roland M. Schmid, Moti Liscovitch, Maria Shatz, Katrin Mair, Michaela Hiber, Jie Chen, Mark Juhasz, Christoph Röcken, Xiangbin Xing, Elke Burgermeister
Supplementary Figure 1 from Differential Expression and Function of Caveolin-1 in Human Gastric Cancer Progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9de97ca0c85480101cb58d29271abdc0
https://doi.org/10.1158/0008-5472.22368683
https://doi.org/10.1158/0008-5472.22368683
Autor:
Matthias P.A. Ebert, Roland M. Schmid, Moti Liscovitch, Maria Shatz, Katrin Mair, Michaela Hiber, Jie Chen, Mark Juhasz, Christoph Röcken, Xiangbin Xing, Elke Burgermeister
Supplementary Figure 2 from Differential Expression and Function of Caveolin-1 in Human Gastric Cancer Progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4355823a49c4dc72a29a0877ee662a91
https://doi.org/10.1158/0008-5472.22368680
https://doi.org/10.1158/0008-5472.22368680
Autor:
Matthias P.A. Ebert, Roland M. Schmid, Moti Liscovitch, Maria Shatz, Katrin Mair, Michaela Hiber, Jie Chen, Mark Juhasz, Christoph Röcken, Xiangbin Xing, Elke Burgermeister
Caveolin-1 is a scaffold protein of caveolae that acts as a tumor modulator by interacting with cell adhesion molecules and signaling receptors. The role of caveolin-1 in the pathogenesis of gastric cancer (GC) is currently unknown. We show by confoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::326a2f44545a03e22465e0370e909b7f
https://doi.org/10.1158/0008-5472.c.6496067
https://doi.org/10.1158/0008-5472.c.6496067
Autor:
Stephan Drexler, Chen Cai, Anna-Lena Hartmann, Denise Moch, Haristi Gaitantzi, Theresa Ney, Malin Kraemer, Yuan Chu, Yuwei Zheng, Mohammad Rahbari, Annalena Treffs, Alena Reiser, Bénédicte Lenoir, Nektarios A. Valous, Dirk Jäger, Emrullah Birgin, Tejas A. Sawant, Qi Li, Keshu Xu, Lingyue Dong, Mirko Otto, Timo Itzel, Andreas Teufel, Norbert Gretz, Lukas J.A.C. Hawinkels, Aránzazu Sánchez, Blanca Herrera, Rudolf Schubert, Han Moshage, Christoph Reissfelder, Matthias P.A. Ebert, Nuh N. Rahbari, Katja Breitkopf-Heinlein
Publikováno v:
Molecular and Cellular Endocrinology. 570:111934
believed to be mainly produced in the liver. The serum levels of BMP-9 were reported to be reduced in newly diagnosed diabetic patients and BMP-9 overexpression ameliorated steatosis in the high fat diet-induced obesity mouse model. Furthermore, inje
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9f7a167dc4c18a30e8226c4a4fc6ae6
https://doi.org/10.1016/j.mce.2023.111934
https://doi.org/10.1016/j.mce.2023.111934