Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Matthias Naumer"'
Autor:
John R White, Marla Abodeely, Sammina Ahmed, Gaël Debauve, Evan Johnson, Debra M Meyer, Ned M Mozier, Matthias Naumer, Alessandra Pepe, Isam Qahwash, Edward Rocnik, Jeffrey G Smith, Elaine SE Stokes, Jeffrey J Talbot, Pin Yee Wong
Publikováno v:
BioTechniques, Vol 67, Iss 3, Pp 126-137 (2019)
Biological activity is a critical quality attribute for biopharmaceuticals, which is accurately measured using an appropriate relative potency bioassay. Developing a bioassay is a complex, rigorous undertaking that needs to address several challenges
Externí odkaz:
https://doaj.org/article/a956d410bab14152a653a980043013fe
Autor:
Ned M. Mozier, Gaël Debauve, Evan Johnson, Alessandra Pepe, Marla Abodeely, Matthias Naumer, Jeffrey J Talbot, Sammina Ahmed, Edward Rocnik, John R. White, Elaine Se Stokes, Pin Yee Wong, Isam Qahwash, Debra M. Meyer, Jeffrey G. Smith
Publikováno v:
BioTechniques. 67:126-137
Biological activity is a critical quality attribute for biopharmaceuticals, which is accurately measured using an appropriate relative potency bioassay. Developing a bioassay is a complex, rigorous undertaking that needs to address several challenges
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1834b7c3227259667d10c34ef99ffc1
https://doi.org/10.2144/btn-2019-0031
https://doi.org/10.2144/btn-2019-0031
Autor:
Jürgen A. Kleinschmidt, Christina Raupp, Timothy S. Baker, Robert Ng, Norman H. Olson, Robert McKenna, Ruth Popa-Wagner, Brittney L. Gurda, Matthias Naumer, Mavis Agbandje-McKenna
Publikováno v:
Journal of Virology. 86:7739-7751
Adeno-associated viruses (AAVs) are small single-stranded DNA viruses that can package and deliver nongenomic DNA for therapeutic gene delivery. AAV8, a liver-tropic vector, has shown great promise for the treatment of hemophilia A and B. However, as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::406ce18c44a5a59c4d2f7d768d3a5b4c
https://doi.org/10.1128/jvi.00218-12
https://doi.org/10.1128/jvi.00218-12
Autor:
Karen Nieto, Matthias Naumer, Christian Panke, Florian Sonntag, Jürgen A. Kleinschmidt, Ruth Popa-Wagner, Norman E. Davey, Kristin Schmidt
Adeno-associated virus (AAV) capsid assembly requires expression of the assembly-activating protein (AAP) together with capsid proteins VP1, VP2, and VP3. AAP is encoded by an alternative open reading frame of the cap gene. Sequence analysis and site
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::394d4ed51a28091a1abaf3fb5bde2da6
https://europepmc.org/articles/PMC3497687/
https://europepmc.org/articles/PMC3497687/
Autor:
Jürgen A. Kleinschmidt, Brittney L. Gurda, Matthias Naumer, Oliver J. Müller, Mavis Agbandje-McKenna, Christina Raupp
Adeno-associated virus (AAV) has attracted considerable interest as a vector for gene therapy owing its lack of pathogenicity and the wealth of available serotypes with distinct tissue tropisms. One of the most promising isolates for vector developme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4838dcd1c6f2cf37eb13e86f0caa3ad
https://europepmc.org/articles/PMC3416165/
https://europepmc.org/articles/PMC3416165/
Publikováno v:
The Journal of general virology. 93(Pt 10)
Vectors based on adeno-associated virus serotype 2 (AAV2) belong to today’s most promising and most frequently used viral vectors in human gene therapy. Like in many other vector systems, the broad but non-specific tropism limits their use for cert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a071f802657cba9d7ba3a6c8488e634d
https://pubmed.ncbi.nlm.nih.gov/22764318
https://pubmed.ncbi.nlm.nih.gov/22764318
Autor:
Jürgen A. Kleinschmidt, Stefan Michelfelder, Oliver Müller, Martin Trepel, Antje Reuter, Ying Ying, Matthias Naumer
Libraries based on the insertion of random peptide ligands into the capsid of adeno-associated virus type 2 (AAV2) have been widely used to improve the efficiency and selectivity of the AAV vector system. However, so far only libraries of 7-mer pepti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a754157f7867485bedde045d71d990d8
https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/72285
https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/72285
Autor:
Peter Scheurich, Roman Fischer, Klaus Pfizenmaier, Anja Krippner-Heidenreich, Matthias Naumer, Olaf Maier
Publikováno v:
Cellular signalling. 23(1)
Endocytosis is an important mechanism to regulate tumor necrosis factor (TNF) signaling. In contrast to TNF receptor 1 (TNFR1; CD120a), the relevance of receptor internalization for signaling as well as the fate and route of internalized TNF receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c465295322e261ce90ff7132bb6fb388
https://pubmed.ncbi.nlm.nih.gov/20807567
https://pubmed.ncbi.nlm.nih.gov/20807567
Publikováno v:
Advances in Human-Computer Interaction ISBN: 9783540601456
Very many people today suffer from foot deformations such as flat feet or hollow feet to name only two out of very many. Their detection used to be carried out through either visual impression, X-ray or plaster cast (where the diagnosis is done after
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13e308c32455c3622ef2d7afdf4a8967
https://doi.org/10.1007/978-3-642-85220-6_24
https://doi.org/10.1007/978-3-642-85220-6_24