Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Matthias Muhar"'
Autor:
Jeannine Diesch, Marguerite-Marie Le Pannérer, René Winkler, Raquel Casquero, Matthias Muhar, Mark van der Garde, Michael Maher, Carolina Martínez Herráez, Joan J. Bech-Serra, Michaela Fellner, Philipp Rathert, Nigel Brooks, Lurdes Zamora, Antonio Gentilella, Carolina de la Torre, Johannes Zuber, Katharina S. Götze, Marcus Buschbeck
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Azacitidine (AZA) treatment is used for patients with myelodysplasias that cannot undergo bone marrow transplantation; however, AZA treatment is only partially effective. Here the authors show synergy of AZA with compounds inhibiting the chromatin re
Externí odkaz:
https://doaj.org/article/d0619bde27374a0bbc9ce933934d9f91
Autor:
Tobias Neumann, Veronika A. Herzog, Matthias Muhar, Arndt von Haeseler, Johannes Zuber, Stefan L. Ameres, Philipp Rescheneder
Publikováno v:
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-16 (2019)
Abstract Background Methods to read out naturally occurring or experimentally introduced nucleic acid modifications are emerging as powerful tools to study dynamic cellular processes. The recovery, quantification and interpretation of such events in
Externí odkaz:
https://doaj.org/article/39292a6c04f248eeb835ced54223a359
Autor:
Anna Skucha, Jessica Ebner, Johannes Schmöllerl, Mareike Roth, Thomas Eder, Adrián César-Razquin, Alexey Stukalov, Sarah Vittori, Matthias Muhar, Bin Lu, Martin Aichinger, Julian Jude, André C. Müller, Balázs Győrffy, Christopher R. Vakoc, Peter Valent, Keiryn L. Bennett, Johannes Zuber, Giulio Superti-Furga, Florian Grebien
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
In leukemia, diverse fusion proteins involving the MLL gene can drive oncogenic activity. Here, the authors describe a dependency of MLL-leukemia cells on the methyltransferase SETD2 to maintain genomic integrity during leukemia initiation and mainte
Externí odkaz:
https://doaj.org/article/c65cecc9bf1145a685881a4d0ac0ba9d
Autor:
Christof Fellmann, Thomas Hoffmann, Vaishali Sridhar, Barbara Hopfgartner, Matthias Muhar, Mareike Roth, Dan Yu Lai, Inês A.M. Barbosa, Jung Shick Kwon, Yuanzhe Guan, Nishi Sinha, Johannes Zuber
Publikováno v:
Cell Reports, Vol 5, Iss 6, Pp 1704-1713 (2013)
Short hairpin RNA (shRNA) technology enables stable and regulated gene repression. For establishing experimentally versatile RNAi tools and minimizing toxicities, synthetic shRNAs can be embedded into endogenous microRNA contexts. However, due to our
Externí odkaz:
https://doaj.org/article/989d8540a74d47cb99c674fb1963f415
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e68168 (2013)
Protein S-nitrosylation, the covalent attachment of a nitroso moiety to thiol groups of specific cysteine residues, is one of the major pathways of nitric oxide signaling. Hundreds of proteins are subject to this transient post-translational modifica
Externí odkaz:
https://doaj.org/article/ecf2865a81ed4fb1b2eb4584e66b9b03
Autor:
Jakob Farnung, Matthias Muhar, Jin Rui Liang, Kateryna A. Tolmachova, Roger M. Benoit, Jacob E. Corn, Jeffrey W. Bode
Publikováno v:
ACS Central Science, 9 (5)
Macroautophagy is one of two major degradation systems in eukaryotic cells. Regulation and control of autophagy are often achieved through the presence of short peptide sequences called LC3 interacting regions (LIR) in autophagy-involved proteins. Us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b10ab1e80168ebafb5cfe50af555de67
https://doi.org/10.1021/acscentsci.3c00009
https://doi.org/10.1021/acscentsci.3c00009
Autor:
Jakob Farnung, Matthias Muhar, Jin Rui Liang, Kateryna A. Tolmachova, Roger M. Benoit, Jacob E. Corn, Jeffrey W. Bode
Macroautophagy is one of two major degradation systems in eukaryotic cells. Regulation and control of autophagy is often achieved through the presence of short peptide sequences called LC3 interacting regions (LIR) in autophagy-involved proteins. Usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15f22cc996e25ad15b4f0f6d80ef1bfd
https://doi.org/10.1101/2022.08.02.502437
https://doi.org/10.1101/2022.08.02.502437
Autor:
Antonio Gentilella, Johannes Zuber, Marguerite-Marie Le Pannérer, Carolina De La Torre, Michael Maher, René Winkler, Carolina Martínez Herráez, Lurdes Zamora, Joan Josep Bech-Serra, Matthias Muhar, Nigel Brooks, Marcus Buschbeck, Katharina Götze, Michaela Fellner, Mark van der Garde, Philipp Rathert, Raquel Casquero, Jeannine Diesch
Publikováno v:
Nature Communications
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The nucleotide analogue azacitidine (AZA) is currently the best treatment option for patients with high-risk myelodysplastic syndromes (MDS). However, only half of treated patients respond and of these almost all eventually relapse. New treatment opt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0435f0addf061fc6e532fd6d31125fa2
https://ddd.uab.cat/record/270585
https://ddd.uab.cat/record/270585
Autor:
Tobias Neumann, Mikhail Spivakov, Jan-Michael Peters, Wen Tang, Valeriya Malysheva, Michiel J. Thiecke, Gordana Wutz, Stephen Bevan, Stefan Schoenfelder, Matthias Muhar, Roman R. Stocsits, Peter Fraser, Johannes Zuber
It is currently assumed that 3D chromosomal organisation plays a central role in transcriptional control. However, recent evidence shows that steady-state transcription of only a minority of genes is affected by depletion of architectural proteins su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2299a3e16fa5822f8147d03146523245
https://doi.org/10.1101/2020.02.10.941989
https://doi.org/10.1101/2020.02.10.941989
Autor:
Jan Ellenberg, Csilla Várnai, David A. Cisneros, Jan-Michael Peters, Johannes Zuber, Moritz Kueblbeck, Birgit Koch, Wen Tang, Stefan Schoenfelder, Matthias Muhar, M. Julius Hossain, Gregor Jessberger, Nike Walther, Gordana Wutz, Roman R. Stocsits, Peter Fraser, Kota Nagasaka
Publikováno v:
The EMBO Journal. 36:3573-3599
Mammalian genomes are spatially organized into compartments, topologically associating domains (TADs), and loops to facilitate gene regulation and other chromosomal functions. How compartments, TAD ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5d39a9929dd5526d318931f38173d45
https://doi.org/10.15252/embj.201798004
https://doi.org/10.15252/embj.201798004