Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Matthias Lipfert"'
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0247684 (2021)
Superoxide dismutase 1 (SOD1) is known to be involved in the pathogenesis of Amyotrophic Lateral Sclerosis (ALS) and is therefore considered to be an important ALS drug target. Identifying potential drug leads that bind to SOD1 and characterizing the
Externí odkaz:
https://doaj.org/article/dfe51f8d9c44490f9b18623437a3e0d9
Autor:
Ignacio Sottorff, Jutta Wiese, Matthias Lipfert, Nils Preußke, Frank D. Sönnichsen, Johannes F. Imhoff
Publikováno v:
Microorganisms, Vol 7, Iss 6, p 166 (2019)
As Streptomyces have shown an outstanding capacity for drug production, different campaigns in geographically distant locations currently aim to isolate new antibiotic producers. However, many of these newly isolated Streptomyces strains are classifi
Externí odkaz:
https://doaj.org/article/cbf9a61235e040a7968eced011067f8f
Autor:
Ignacio Sottorff, Sven Künzel, Jutta Wiese, Matthias Lipfert, Nils Preußke, Frank D. Sönnichsen, Johannes F. Imhoff
Publikováno v:
Marine Drugs, Vol 17, Iss 3, p 154 (2019)
The presence of two known anthraquinones, Lupinacidin A and Galvaquinone B, which have antitumor activity, has been identified in the sea anemone (Gyractis sesere) from Easter Island. So far, these anthraquinones have been characterized from terrestr
Externí odkaz:
https://doaj.org/article/bd9de57c470a4ceebb92a72f31251acb
Autor:
Yeganeh Khaniani, Matthias Lipfert, Dipanjan Bhattacharyya, Rolando Perez Pineiro, Jiamin Zheng, David S. Wishart
Publikováno v:
Metabolites, Vol 8, Iss 4, p 80 (2018)
An improved method to synthesize the highly abundant and biomedically important urinary metabolite 3-(3-hydroxyphenyl)-3-hydroxypropionic acid (HPHPA) is reported. The modified protocol is based on an indium-mediated sonochemical Reformatsky reaction
Externí odkaz:
https://doaj.org/article/bd6c001c45ad4077afbc168264617b9a
Autor:
David S, Wishart, Manoj, Rout, Brian L, Lee, Mark, Berjanskii, Marcia, LeVatte, Matthias, Lipfert
Publikováno v:
Handbook of experimental pharmacology.
While NMR-based metabolomics is only about 20 years old, NMR has been a key part of metabolic and metabolism studies for40 years. Historically, metabolic researchers used NMR because of its high level of reproducibility, superb instrument stability,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::033f3b7d0a1ccfc89630570d1b29fafe
https://pubmed.ncbi.nlm.nih.gov/36271165
https://pubmed.ncbi.nlm.nih.gov/36271165
Autor:
Matthias Lipfert, Widukind Moormann, Nils Preußke, Katrin Bamberg, Frank D. Sönnichsen, Rainer Herges
Publikováno v:
Organic & Biomolecular Chemistry. 18:2650-2660
Diazocines are characterized by extraordinary photochemical properties rendering them of particular interest for switching the conformation of biomolecules with visible light. Current developments afford synthetic access to unprecedented diazocine de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cafd3e99e544472450c457aab87a15f6
https://doi.org/10.1039/c9ob02442e
https://doi.org/10.1039/c9ob02442e
Autor:
David S. Wishart, Manoj Rout, Brian L. Lee, Mark Berjanskii, Marcia LeVatte, Matthias Lipfert
Publikováno v:
Metabolomics and Its Impact on Health and Diseases ISBN: 9783031268588
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9a8b7db7f2a9ee55bb3f25ff6b060c6
https://doi.org/10.1007/164_2022_613
https://doi.org/10.1007/164_2022_613
Publikováno v:
Biochemistry. 60(42)
α-Helical antimicrobial peptides (αAMPs) are among the potential candidates for new anti-infectives to tackle the global crisis in antibiotic resistance, but they suffer from low bioavailability due to high susceptibility to enzymatic degradation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cff2a28add6cb085b8d7dc8d9e7cb42
https://pubmed.ncbi.nlm.nih.gov/34613690
https://pubmed.ncbi.nlm.nih.gov/34613690
Publikováno v:
Analytical Biochemistry. 580:1-13
The presence of ascorbate in human urine has been shown to be a useful dietary, fruit or vitamin C intake biomarker. More recently it has been discovered that ascorbate levels in urine can be used to facilitate the detection of precancerous colorecta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25f31b37ab026005d007c90dfd6b96f7
https://doi.org/10.1016/j.ab.2019.05.015
https://doi.org/10.1016/j.ab.2019.05.015
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2037
Nuclear magnetic resonance (NMR) spectroscopy is becoming increasingly automated. Most modern NMR spectrometers are now equipped with auto-tune/auto-match probes along with automated locking and shimming systems. Likewise, more and more instruments,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f27b0dc0b537167e7cfd326e9ad325ea
https://pubmed.ncbi.nlm.nih.gov/31463859
https://pubmed.ncbi.nlm.nih.gov/31463859