Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Matthias Linke"'
Autor:
Laura Holthöfer, Stefan Diederich, Verena Haug, Lioba Lehmann, Charlotte Hewel, Norbert W. Paul, Susann Schweiger, Susanne Gerber, Matthias Linke
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-8 (2024)
Abstract Adaptive nanopore sequencing as a diagnostic method for imprinting disorders and episignature analysis revealed an intragenic duplication of Exon 6 and 7 in UBE3A (NM_000462.5) in a patient with relatively mild Angelman-like syndrome. In an
Externí odkaz:
https://doaj.org/article/3d509ae199d648309382254570d89142
Autor:
Hanno Schmidt, Niels Lemmermann, Matthias Linke, Sven-Ernö Bikár, Stefan Runkel, Susann Schweiger-Seemann, Susanne Gerber, André Michel, Thomas Hankeln, Marina Veith, Wolfgang Kohnen, Bodo Plachter
Publikováno v:
Infection Prevention in Practice, Vol 6, Iss 3, Pp 100383- (2024)
Summary: Background: During the SARS-CoV-2 pandemic, dominant viral variants were repeatedly replaced by new variants with altered properties, frequently changing the dynamics of the infection event, as well as the effectiveness of vaccines and thera
Externí odkaz:
https://doaj.org/article/7aacbde8c9f04568b116d07ff6527a72
Autor:
Min-Kyeung Choi, Alexander Cook, Kanak Mungikar, Helen Eachus, Anna Tochwin, Matthias Linke, Susanne Gerber, Soojin Ryu
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110160- (2024)
Summary: Early life stress (ELS) is a major risk factor for developing psychiatric disorders, with glucocorticoids (GCs) implicated in mediating its effects in shaping adult phenotypes. In this process, exposure to high levels of developmental GC (hd
Externí odkaz:
https://doaj.org/article/02720797642941e0a2fce22a09a4bec9
Autor:
Danuta Galetzka, Julia Böck, Lukas Wagner, Marcus Dittrich, Olesja Sinizyn, Marco Ludwig, Heidi Rossmann, Claudia Spix, Markus Radsak, Peter Scholz-Kreisel, Johanna Mirsch, Matthias Linke, Walburgis Brenner, Manuela Marron, Alicia Poplawski, Thomas Haaf, Heinz Schmidberger, Dirk Prawitt
Publikováno v:
EXCLI Journal : Experimental and Clinical Sciences, Vol 21, Pp 117-143 (2022)
Most childhood cancers occur sporadically and cannot be explained by an inherited mutation or an unhealthy lifestyle. However, risk factors might trigger the oncogenic transformation of cells. Among other regulatory signals, hypermethylation of RAD9A
Externí odkaz:
https://doaj.org/article/4a24ce34995f4364bc5fbdf365f6bd5d
Autor:
Giulia Treccani, Hatice Yigit, Thomas Lingner, Vanessa Schleuβner, Franziska Mey, Michael A. van der Kooij, Malin Wennström, David P. Herzog, Matthias Linke, Markus Fricke, Michael J. Schmeisser, Gregers Wegener, Thomas Mittmann, Jacqueline Trotter, Marianne B. Müller
Publikováno v:
Neurobiology of Stress, Vol 15, Iss , Pp 100338- (2021)
The precise mechanisms underlying the detrimental effects of early life adversity (ELA) on adult mental health remain still elusive. To date, most studies have exclusively targeted neuronal populations and not considered neuron-glia crosstalk as a cr
Externí odkaz:
https://doaj.org/article/d9eca5eca6cb4e2eae4d12198f50d25b
Autor:
Azra Fatima, Shao Kaifeng, Sven Dittmann, Guoxing Xu, Manoj K Gupta, Matthias Linke, Ulrich Zechner, Filomain Nguemo, Hendrik Milting, Martin Farr, Jürgen Hescheler, Tomo Sarić
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83005 (2013)
Long QT syndromes (LQTS) are heritable diseases characterized by prolongation of the QT interval on an electrocardiogram, which often leads to syncope and sudden cardiac death. Here we report the generation of induced pluripotent stems (iPS) cells fr
Externí odkaz:
https://doaj.org/article/e7b26192d1fe4ce98fde4610894b9064
Autor:
Anne Rieusset, Fabienne Schaller, Unga Unmehopa, Valery Matarazzo, Françoise Watrin, Matthias Linke, Beatrice Georges, Jocelyn Bischof, Femke Dijkstra, Monique Bloemsma, Severine Corby, François J Michel, Rachel Wevrick, Ulrich Zechner, Dick Swaab, Keith Dudley, Laurent Bezin, Françoise Muscatelli
Publikováno v:
PLoS Genetics, Vol 9, Iss 9, p e1003752 (2013)
Genomic imprinting is a process that causes genes to be expressed from one allele only according to parental origin, the other allele being silent. Diseases can arise when the normally active alleles are not expressed. In this context, low level of e
Externí odkaz:
https://doaj.org/article/f2c3758e8bac44f1925fec2d0cfa57ad
Autor:
Leonie Frommherz, Katalin Komlosi, Charlotte Hewel, Julia Kopp, Malin Dewenter, Andreas Zimmer, Oliver Bartsch, Matthias Linke, Kristin Technau‐Hafsi, Susanne Gerber, Judith Fischer, Cristina Has
Publikováno v:
Journal of the European Academy of Dermatology and Venereology. 37:817-822
Most cases of hereditary ichthyoses present with generalized scaling and skin dryness. However, in some cases skin involvement is restricted to particular body regions as in acral lamellar ichthyosis.We report on the genetic basis of acral ichthyosis
Publikováno v:
The Journal of Physical Chemistry C. 125:7721-7727
Publikováno v:
The Journal of Physical Chemistry C. 124:16069-16075
Surface-sensitive vibrational sum frequency spectroscopy (vSFS) has been utilized to study the adsorption chemistry of small alcohols, namely, methanol, ethanol, 1-propanol, and 2-propanol on TiO2 ...