Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Matthias Krusch"'
Autor:
Helmut Rainer Salih, Helga Maria Schmetzer, Alexander Wacker, Katrin Miriam Baltz, Mercedes Kloss, Benjamin Joachim Schmiedel, Matthias Krusch, Tina Baessler
The reciprocal interaction of tumor cells with the immune system is influenced by various members of the tumor necrosis factor (TNF)/TNF receptor (TNFR) family, and recently, glucocorticoid-induced TNFR-related protein (GITR) was shown to stimulate a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72191a9f473a95ea6582e32b1a2124b9
https://doi.org/10.1158/0008-5472.c.6499916.v1
https://doi.org/10.1158/0008-5472.c.6499916.v1
Autor:
Helmut Rainer Salih, Helga Maria Schmetzer, Alexander Wacker, Katrin Miriam Baltz, Mercedes Kloss, Benjamin Joachim Schmiedel, Matthias Krusch, Tina Baessler
Supplementary Figure 1 from Glucocorticoid-Induced Tumor Necrosis Factor Receptor–Related Protein Ligand Subverts Immunosurveillance of Acute Myeloid Leukemia in Humans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71419390672097bd82183f7c19d4e347
https://doi.org/10.1158/0008-5472.22381577
https://doi.org/10.1158/0008-5472.22381577
Autor:
Alexander Wacker, Hans-Georg Rammensee, Benjamin J Schmiedel, Frank Grünebach, Helmut R. Salih, Jean Enno Charton, Tina Baessler, Matthias Krusch
Publikováno v:
Blood. 115:3058-3069
Natural killer (NK) cells play an important role in the immunosurveillance of leukemia. Their reactivity is governed by a balance of activating and inhibitory receptors including various members of the tumor necrosis factor receptor (TNFR) family. He
Autor:
Frank Grünebach, Theresa Placke, Alexander Steinle, Julia Salih, Julia Hilpert, Helmut R. Salih, Matthias Krusch
Publikováno v:
International Journal of Cancer. 127:2119-2128
In chronic myeloid leukemia (CML), BCR/ABL-mediated oncogenic signaling can be targeted with the BCR/ABL-inhibitors Imatinib, Nilotinib and Dasatinib. However, these agents may also affect anti-tumor immunity. Here, we analyzed the effects of the 3 B
Autor:
Julia Salih, Matthias Krusch, Tina Baessler, Kerstin Maria Kampa, Frank Mayer, Manuela Schlicke, Helmut R. Salih
Publikováno v:
The Journal of Immunology. 183:8286-8294
Sunitinib and Sorafenib are protein kinase inhibitors (PKI) approved for treatment of patients with advanced renal cell cancer (RCC). However, long-term remissions of advanced RCC have only been observed after IL-2 treatment, which underlines the imp
Autor:
Mercedes Kloss, Helga Schmetzer, Matthias Krusch, Helmut R. Salih, Tina Baessler, Benjamin J Schmiedel, Katrin M. Baltz, Alexander Wacker
Publikováno v:
Cancer Research. 69:1037-1045
The reciprocal interaction of tumor cells with the immune system is influenced by various members of the tumor necrosis factor (TNF)/TNF receptor (TNFR) family, and recently, glucocorticoid-induced TNFR-related protein (GITR) was shown to stimulate a
Autor:
Alexander Steinle, Patrice Decker, Gundram Jung, Matthias Krusch, Katrin M. Baltz, Mercedes Kloss, Hans-Georg Rammensee, Tina Baessler, Helmut R. Salih
Publikováno v:
The Journal of Immunology. 181:6711-6719
Reciprocal interactions between NK cells and dendritic cells have been shown to influence activation of NK cells, maturation, or lysis of dendritic cells and subsequent adaptive immune responses. However, little is known about the crosstalk between m
Autor:
Peter Brossart, Anita Bringmann, Benjamin J Schmiedel, Katrin M. Baltz, Helmut R. Salih, Matthias Krusch, Tina Baessler
Publikováno v:
Blood. 112:3735-3743
NK cell anti-tumor reactivity is governed by a balance of activating and inhibitory receptors including various TNF receptor (TNFR) family members. Here we report that human tumor cells release a soluble form of the TNF family member Glucocorticoid-I
Autor:
Matthias Krusch, Bin Zhong, Helmut R. Salih, Jeffrey S. Painter, Sheng Wei, Pearlie K. Epling-Burnette, Edna Ku, David Boulware, Lynn C. Moscinski, Julie Y. Djeu, JianXiang Zou, Dana E. Rollison, Alan F. List, Fanqi Bai
Publikováno v:
Blood. 109:4816-4824
Myelodysplastic syndromes (MDS) are characterized by ineffective hematopoiesis with potential for progression to acute myeloid leukemia (AML). We compared natural killer (NK) cytolytic function in 48 MDS patients with 37 healthy donors and found redu
Autor:
Hans-Jochem Kolb, Helga Schmetzer, N. Hentschel, Matthias Krusch, Helmut R. Salih, Peter A. Kiener
Publikováno v:
European Journal of Haematology. 77:91-101
CD178 (Fas/APO-1 ligand) and CD137 ligand (CD137L) have previously been described in sera of patients with various malignancies and play an important role in the pathogenesis of various diseases. Recently, we demonstrated that low levels of soluble (