Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Matthias Kotzsch"'
Autor:
Susanne Soelch, Nathalie Beaufort, Daniela Loessner, Matthias Kotzsch, Ute Reuning, Thomas Luther, Thomas Kirchner, Viktor Magdolen
Publikováno v:
Molecular Medicine, Vol 27, Iss 1, Pp 1-17 (2021)
Abstract Background The small GTP-binding protein Rab31 plays an important role in the modulation of tumor biological-relevant processes, including cell proliferation, adhesion, and invasion. As an underlying mechanism, Rab31 is presumed to act as a
Externí odkaz:
https://doaj.org/article/06f73efbd7294843bc4778a9a6e7b247
Autor:
Weiwei Gong, Yueyang Liu, Christof Seidl, Eleftherios P. Diamandis, Marion Kiechle, Enken Drecoll, Matthias Kotzsch, Viktor Magdolen, Julia Dorn
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background In ovarian cancer, dysregulation of mRNA expression of several components of the family of the kallikrein-related peptidases (KLKs) is observed. In this study, we have analyzed the KLK5 mRNA expression pattern in tumor tissue of p
Externí odkaz:
https://doaj.org/article/a33ba9ca6f6a46c78588592b441d9223
Autor:
Weiwei Gong, Yueyang Liu, Christof Seidl, Tobias Dreyer, Enken Drecoll, Matthias Kotzsch, Holger Bronger, Julia Dorn, Viktor Magdolen
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212968 (2019)
Overexpression of several members of the kallikrein-related peptidase (KLK) family, including KLK4, has been reported in ovarian cancer tissue, consistent with the fact that elevated levels of KLK protein are often also found in serum and in effusion
Externí odkaz:
https://doaj.org/article/fd32636242e84c4dacce1148406827ad
Autor:
Xiaocong Geng, Yueyang Liu, Sandra Diersch, Matthias Kotzsch, Sabine Grill, Wilko Weichert, Marion Kiechle, Viktor Magdolen, Julia Dorn
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0186847 (2017)
KLK9, 10, 11, and 15 may represent potential cancer biomarkers for evaluating ovarian cancer prognosis. In the present study, we selected a homogeneous cohort including 139 patients of advanced high-grade serous ovarian cancer (FIGO stage III/IV) and
Externí odkaz:
https://doaj.org/article/310a3cf6721c47c28051a8ba06fc215e
Autor:
Anna Lehner, Viktor Magdolen, Tibor Schuster, Matthias Kotzsch, Marion Kiechle, Alfons Meindl, Fred C G J Sweep, Paul N Span, Eva Gross
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60359 (2013)
HTRA1 is a highly conserved serine protease which has been implicated in suppression of epithelial-to-mesenchymal-transition (EMT) and cell motility in breast cancer. Its prognostic relevance for breast cancer is unclear so far. Therefore, we evaluat
Externí odkaz:
https://doaj.org/article/c159e79a9b6943129bf471955d05f6aa
Autor:
Feng Yang, Viktor Magdolen, Manfred Schmitt, Julia Dorn, Oliver Schilling, Matthias Kotzsch, Anja Rockstroh, Christof Seidl, Daniela Loessner, Judith A. Clements, Ping Wang, Enken Drecoll
Publikováno v:
British Journal of Cancer
Background Tissue kallikrein-related peptidases 4, 5, 6 and 7 (KLK4–7) strongly increase the malignancy of ovarian cancer cells. Deciphering their downstream effectors, we aimed at finding new potential prognostic biomarkers and treatment targets f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3616211c29a2d803a54cb5e652028be
https://doi.org/10.1038/s41416-018-0260-1
https://doi.org/10.1038/s41416-018-0260-1
Autor:
Wilko Weichert, Viktor Magdolen, Rudolf Napieralski, Manfred Schmitt, Julia Dorn, Larissa Dettmar, Sandra Diersch, Matthias Kotzsch, Dalila Darmoul, Marion Kiechle, Nancy Ahmed
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 144:1109-1118
Gene expression of a variety of the 15 members of the KLK serine protease family is dysregulated in ovarian cancer. We aimed at determining the clinical relevance of KLK13 and KLK14 mRNA expression in tumor tissues of a homogeneous patient cohort aff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88b16a0e5a623194011dd4f205604660
https://doi.org/10.1007/s00432-018-2623-7
https://doi.org/10.1007/s00432-018-2623-7
Publikováno v:
Atlas of Genetics and Cytogenetics in Oncology and Haematology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31d58a8e1bc9c4881ba53163308f24e8
https://doi.org/10.4267/2042/66072
https://doi.org/10.4267/2042/66072
Autor:
Matthias, Kotzsch, Thomas, Kirchner, Susanne, Soelch, Sonja, Schäfer, Katrin, Friedrich, Gustavo, Baretton, Viktor, Magdolen, Thomas, Luther
Publikováno v:
American journal of cancer research. 7(9)
Dysregulated expression of rab31, a member of the large Rab protein family of the Ras superfamily of small GTPases, has been observed in several types of cancer, including breast cancer. Rab31, depending on its expression level, may regulate the swit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bbd3f5b2394ed9f1b1f703a39ed3ef6d
https://pubmed.ncbi.nlm.nih.gov/28979817
https://pubmed.ncbi.nlm.nih.gov/28979817
Publikováno v:
Strahlentherapie und Onkologie. 190:276-282
Hypoxic radioresistance plays a critical role in the radiotherapy of cancer and adversely impacts prognosis and treatment response. This prospective study investigated the interrelationship and the prognostic significance of several hypoxia-related p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16fe056d6af11bcf3dfb83e47cfab285
https://doi.org/10.1007/s00066-013-0484-1
https://doi.org/10.1007/s00066-013-0484-1