Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Matthias Koerner"'
Publikováno v:
Bioorganic & Medicinal Chemistry. 26:970-976
A scalable 5-step synthesis of the diazacarbazole derivative 1 used as tau PET tracer precursor is reported. Key features of this synthesis include a Buchwald-Hartwig amination, a Pd catalyzed CH activation and a Suzuki-Miyaura cross-coupling.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38113eab8b54092d1cfce0e5acb11b83
https://doi.org/10.1016/j.bmc.2017.10.007
https://doi.org/10.1016/j.bmc.2017.10.007
Autor:
Michael, Honer, Luca, Gobbi, Henner, Knust, Hiroto, Kuwabara, Dieter, Muri, Matthias, Koerner, Heather, Valentine, Robert F, Dannals, Dean F, Wong, Edilio, Borroni
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 59(4)
Tau aggregates and amyloid-β (Aβ) plaques are key histopathologic features in Alzheimer disease (AD) and are considered targets for therapeutic intervention as well as biomarkers for diagnostic in vivo imaging agents. This article describes the pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1d20376545a88005d6fff953fc5a54bb
https://pubmed.ncbi.nlm.nih.gov/28970331
https://pubmed.ncbi.nlm.nih.gov/28970331
Publikováno v:
ChemInform. 30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88dc2a01f81b510f9974760a792ff450
https://doi.org/10.1002/chin.199914111
https://doi.org/10.1002/chin.199914111
Autor:
Matthias Koerner, Elodie Meyer, Ruben Alvarez Sanchez, Daniela Alberati, Bruno Pouzet, P. Malherbe, Joseph G. Wettstein, Daniel Schlatter, Hervé Schaffhauser, Eric Prinssen, Theresa M. Ballard, Tanya L. Wallace, Alexander Flohr, Rosa Maria Rodriguez Sarmiento
Publikováno v:
Schizophrenia Research. 136:S166-S167
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b7bbf46d592aee2595e5ef54d485800
https://doi.org/10.1016/s0920-9964(12)70524-8
https://doi.org/10.1016/s0920-9964(12)70524-8