Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Matthias J E Arlt"'
Autor:
Ana Gvozdenovic, Matthias J E Arlt, Carmen Campanile, Patrick Brennecke, Knut Husmann, Walter Born, Roman Muff, Bruno Fuchs
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60329 (2013)
Osteosarcoma (OS) is the most frequent primary malignant bone cancer in children and adolescents with a high propensity for lung metastasis. Therefore, it is of great importance to identify molecular markers leading to increased metastatic potential
Externí odkaz:
https://doaj.org/article/2d1642759ffe43d095769fde8eab1d58
Autor:
Patrick Brennecke, Matthias J E Arlt, Roman Muff, Carmen Campanile, Ana Gvozdenovic, Knut Husmann, Nathalie Holzwarth, Elisabetta Cameroni, Felix Ehrensperger, Marcus Thelen, Walter Born, Bruno Fuchs
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74045 (2013)
More effective treatment of metastasizing osteosarcoma with a current mean 5-year survival rate of less than 20% requires more detailed knowledge on mechanisms and key regulatory molecules of the complex metastatic process. CXCR4, the receptor of the
Externí odkaz:
https://doaj.org/article/2ed866bc26c84ca29cb72225614364d9
Autor:
Elena, Cambria, Matthias J E, Arlt, Sandra, Wandel, Olga, Krupkova, Wolfgang, Hitzl, Fabian S, Passini, Oliver N, Hausmann, Jess G, Snedeker, Stephen J, Ferguson, Karin, Wuertz-Kozak
Publikováno v:
Cells
Mechanical loading and inflammation interact to cause degenerative disc disease and low back pain (LBP). However, the underlying mechanosensing and mechanotransductive pathways are poorly understood. This results in untargeted pharmacological treatme
Autor:
Matthias J. E. Arlt (AUTHOR), Ingo J. Banke (AUTHOR), Josefine Bertz (AUTHOR), Ram Mohan Ram Kumar (AUTHOR), Roman Muff (AUTHOR), Walter Born (AUTHOR), Bruno Fuchs (AUTHOR)
Publikováno v:
Sarcoma. 2013, p1-13. 13p.
Autor:
Matthias J E, Arlt, Ingo J, Banke, Denise K, Walters, Gabor J, Puskas, Patrick, Steinmann, Roman, Muff, Walter, Born, Bruno, Fuchs
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 29(6)
More effective treatment of patients with metastasizing osteosarcoma (OS) with a mean 5-year survival rate of20% requires more detailed knowledge on the complex mechanisms of metastasis for the design of new drugs, which selectively target metastasiz
Autor:
Sefer, Elezkurtaj, Charlotte, Kopitz, Andrew H, Baker, Alejandra, Perez-Cantó, Matthias J E, Arlt, Rama, Khokha, Bernd, Gansbacher, Martina, Anton, Karsten, Brand, Achim, Krüger
Publikováno v:
The journal of gene medicine. 6(11)
Matrix metalloproteinases (MMPs) are critical for metastasis of tumor cells. Tissue inhibitor of metalloproteinases-1 (TIMP-1), a natural MMP inhibitor, was shown to reduce metastasis in different models. Here, we investigated whether increased TIMP-