Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Matthias Husmann"'
Autor:
Gisela von Hoven, Claudia Neukirch, Martina Meyenburg, Sabine Schmidt, Ana Vences, Carlos R. Osorio, Matthias Husmann, Amable J. Rivas
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Photobacterium damselae subsp. damselae (Pdd) is an emerging pathogen of marine animals that sometimes causes serious infections in humans. Two related pore forming toxins, phobalysins P and C, and damselysin, a phospholipase D, confer strong virulen
Externí odkaz:
https://doaj.org/article/41fd8c29f1984374a79a4302ee7f6970
Autor:
Gisela von Hoven, Amable J. Rivas, Claudia Neukirch, Martina Meyenburg, Qianqian Qin, Sapun Parekh, Nadja Hellmann, Matthias Husmann
Publikováno v:
mBio, Vol 8, Iss 1 (2017)
ABSTRACT Membrane repair emerges as an innate defense protecting target cells against bacterial pore-forming toxins. Here, we report the first paradigm of Ca2+-dependent repair following attack by a small β-pore-forming toxin, namely, plasmid-encode
Externí odkaz:
https://doaj.org/article/a4e4a71cfa2c4c41a7dc138fd91ececc
Publikováno v:
Toxins, Vol 11, Iss 7, p 412 (2019)
Phobalysin P (PhlyP, for photobacterial lysin encoded on a plasmid) is a recently described small β-pore forming toxin of Photobacterium damselae subsp. damselae (Pdd). This organism, belonging to the family of Vibrionaceae, is an emerging pathogen
Externí odkaz:
https://doaj.org/article/7ddc4e4202de483aae822ed1eb5f925d
Publikováno v:
Toxins, Vol 9, Iss 10, p 332 (2017)
The pore forming hemolysin A, Hla, is a major virulence factor of Staphylococcus aureus. Apparently, 1–2 pore(s) per cell suffice(s) to cause cell death. Accumulated experimental evidence points towards a major role of ATP-gated purinergic receptor
Externí odkaz:
https://doaj.org/article/b135650a02e843278a0fbc947e261c30
Autor:
Cheng-Yuan Kao, Ferdinand C O Los, Danielle L Huffman, Shinichiro Wachi, Nicole Kloft, Matthias Husmann, Valbona Karabrahimi, Jean-Louis Schwartz, Audrey Bellier, Christine Ha, Youn Sagong, Hui Fan, Partho Ghosh, Mindy Hsieh, Chih-Shen Hsu, Li Chen, Raffi V Aroian
Publikováno v:
PLoS Pathogens, Vol 7, Iss 3, p e1001314 (2011)
Here we present the first global functional analysis of cellular responses to pore-forming toxins (PFTs). PFTs are uniquely important bacterial virulence factors, comprising the single largest class of bacterial protein toxins and being important for
Externí odkaz:
https://doaj.org/article/33afd7ffdcaa4c2b8670aa81a8cc9d3c
Autor:
Gilles Spoden, Kirsten Freitag, Matthias Husmann, Klaus Boller, Martin Sapp, Carsten Lambert, Luise Florin
Publikováno v:
PLoS ONE, Vol 3, Iss 10, p e3313 (2008)
BACKGROUND: Infectious entry of human papillomaviruses into their host cells is an important step in the viral life cycle. For cell binding these viruses use proteoglycans as initial attachment sites. Subsequent transfer to a secondary receptor molec
Externí odkaz:
https://doaj.org/article/910bc9e89a334a4dad8db03ba46e6bec
S. aureus is one of the most important causes of infectious diseases in hospitalized individuals and outpatients. The majority of clinical isolates secretes large amounts of the small membrane pore-forming α-toxin, alias α-hemolysin, which serves a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::258fcf5c9e72dfb59a16aa6ca04738be
https://doi.org/10.1101/2022.05.11.491455
https://doi.org/10.1101/2022.05.11.491455
Publikováno v:
Biological Chemistry. 400:1261-1276
The small β-pore-forming α-toxin, also termed α-hemolysin or Hla is considered to be an important virulence factor of Staphylococcus aureus. Perforation of the plasma membrane (PM) by Hla leads to uncontrolled flux of ions and water. Already a sma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40b5d73e2cf99d3b3a69a94feea2027d
https://doi.org/10.1515/hsz-2018-0472
https://doi.org/10.1515/hsz-2018-0472
Autor:
Nadja Hellmann, Paul Saftig, Rolf Postina, Amable J. Rivas, Matthias Husmann, Qianqian Qin, Christian Hamm, Stefan Klein, Gisela von Hoven, Sabine Füser, Claudia Neukirch, Martina Meyenburg
Publikováno v:
Biochemical Journal. 473:1929-1940
Staphylococcus aureus is a leading cause of bacterial infections in humans, including life-threatening diseases such as pneumonia and sepsis. Its small membrane-pore-forming α-toxin is considered an important virulence factor. By destroying cell–c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2142e802beb4bb076874fa95cfb0cccc
https://doi.org/10.1042/bcj20160062
https://doi.org/10.1042/bcj20160062
Autor:
Gisela von Hoven, Matthias Husmann
Publikováno v:
Trends in Microbiology. 27:89-90
The membrane pore-forming α-toxin is an important virulence factor of Staphylococcus aureus. Target cells can remove pores from their surface, but recent work shows that α-toxin may undermine this self-defense by clinging to epithelial cell junctio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8132871a250ff701fca6491b8b9cec3b
https://doi.org/10.1016/j.tim.2018.11.010
https://doi.org/10.1016/j.tim.2018.11.010