Zobrazeno 1 - 10 of 13 pro vyhledávání: '"Matthias Hentze"'
1
Improved discovery of RNA-binding protein binding sites in eCLIP data using DEWSeq
Autor: Sudeep Sahadevan, Milad Miladi, Thomas Schwarzl, Matthias Hentze, Benjamin Lang, Rolf Backofen, Gian Gaetano Tartaglia, Wolfgang Huber
Enhanced crosslinking and immunoprecipitation (eCLIP) sequencing is a powerful method for transcriptome-wide detection of binding sites of RNA-binding proteins (RBPs). However, identified crosslink sites can profoundly deviate from experimentally est
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8960114182206922ae55534ccdb7b385
https://doi.org/10.1101/2022.11.15.516416
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2
Small non-coding RNA Interactome Capture reveals pervasive, carbon source-dependent tRNA engagement of yeast glycolytic enzymes
Autor: Claudio Asencio Salcedo, Sudeep Sahadevan, Matthias Hentze, Thomas Schwarzl
Small non-coding RNAs fulfill key functions in cellular and organismal biology, typically working in concert with RNA-binding proteins (RBPs). While proteome-wide methodologies have enormously expanded the repertoire of known RBPs, these methods do n
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d299e8afe5a95c9879382d8f8e05da85
https://doi.org/10.1101/2022.07.14.500110
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3
Regulated poly(A) tail shortening in somatic cells mediated by cap-proximal translational repressor proteins and ribosome association
Autor: Muckenthaler M, Gunkel N, Stripecke R, Matthias Hentze
Publikováno v: EMBL-EBI
The poly(A) tail plays an important role in translation initiation. We report the identification of a mechanism that operates in mammalian somatic cells, and couples mRNA poly(A) tail length with its translation state. The regulation of human ferriti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::fbe7c7759c1fa43614a9b4545b55b4f0
https://pubmed.ncbi.nlm.nih.gov/9292498
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4
Regulated ribosomal frameshifting by an RNA-protein interaction
Autor: Kollmus H, Matthias Hentze, Hauser H
Publikováno v: EMBL-EBI
Ribosomal frameshifting is a translational mechanism used as an essential step in the replication cycle of retroviruses. Programmed frameshifting in retroviral translation involves two sequence elements: A heptanucleotide slippery sequence which indu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c08cec2d89c06c1649fb704c1a802cd2
https://pubmed.ncbi.nlm.nih.gov/8634912
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5
Effect of heparin contained in preparations of small cytoplasmic RNAs on cell-free translation
Autor: He, Johansson, De Groot N, Aa, Hochberg, Matthias Hentze
Publikováno v: EMBL-EBI
It has been reported that small cytoplasmic RNA (scRNA) from human placenta inhibits translation of most mRNAs in both wheat germ extracts and reticulocyte lysates (Lorberboum, H., Digweed, M., Erdmann, V. A., Servadio, Y., Weinstein, D., De Groot, N
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e267e8c4fccd11ce90af3fb97c1ee229
https://pubmed.ncbi.nlm.nih.gov/1703159
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6
The iron-responsive element is the single element responsible for iron-dependent translational regulation of ferritin biosynthesis. Evidence for function as the binding site for a translational repressor
Autor: Sw, Caughman, Matthias Hentze, Ta, Rouault, Jb, Harford, Rd, Klausner
Publikováno v: EMBL-EBI
Ferritin, a cytoplasmic protein critical in iron metabolism, displays iron-dependent regulation of its biosynthetic rate with no corresponding changes in mRNA levels. An iron-responsive element (IRE) has been identified in the 5'-untranslated region
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::220040039698f4c93bb0a24d52e96649
https://pubmed.ncbi.nlm.nih.gov/3198610
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8
Translational control of 5-aminolevulinate synthase mRNA by iron-responsive elements in erythroid cells
Autor: Melefors O, Goossen B, He, Johansson, Stripecke R, Nk, Gray, Matthias Hentze
Publikováno v: Europe PubMed Central
EMBL-EBI
Hemoglobin synthesis in red cells is the major iron utilization pathway in the human body and accounts for80% of systemic iron turnover. The first step in erythroid heme biosynthesis is catalyzed by a tissue-specific isoform of 5-aminolevulinate synt
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c137aeec147015771a4eb4594649663c
http://europepmc.org/abstract/med/8449958
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10
The Drosophila splicing regulator sex-lethal directly inhibits translation of male-specific-lethal 2 mRNA
Autor: Gebauer F, Merendino L, Matthias Hentze, Valcárcel J
Publikováno v: Europe PubMed Central
ResearcherID
EMBL-EBI
Male-specific expression of the protein male-specific-lethal 2 (MSL-2) controls dosage compensation in Drosophila. msl-2 gene expression is inhibited in females by Sex-lethal (SXL), an RNA binding protein known to regulate pre-mRNA splicing. An intro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::37e084d6797eb41d9c2d209a7225a2ac
http://europepmc.org/abstract/med/9570314
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