Zobrazeno 1 - 10
of 254
pro vyhledávání: '"Matthias Gunzer"'
Autor:
Zülal Cibir, Jacqueline Hassel, Justin Sonneck, Lennart Kowitz, Alexander Beer, Andreas Kraus, Gabriel Hallekamp, Martin Rosenkranz, Pascal Raffelberg, Sven Olfen, Kamil Smilowski, Roman Burkard, Iris Helfrich, Ali Ata Tuz, Vikramjeet Singh, Susmita Ghosh, Albert Sickmann, Anne-Kathrin Klebl, Jan Eike Eickhoff, Bert Klebl, Karsten Seidl, Jianxu Chen, Anton Grabmaier, Reinhard Viga, Matthias Gunzer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Autonomous migration is essential for the function of immune cells such as neutrophils and plays an important role in numerous diseases. The ability to routinely measure or target it would offer a wealth of clinical applications. Video micro
Externí odkaz:
https://doaj.org/article/b6ba73ce29c54a989c41e2390aa3764e
Autor:
Daniela Mittermüller, Lucas Otto, Annika Loredana Kilian, Ann-Kathrin Schnormeier, Elisabeth Littwitz-Salomon, Anja Hasenberg, Ulf Dittmer, Matthias Gunzer
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Cytotoxic T lymphocyte (CTL) motility is an important feature of effective CTL responses and is impaired when CTLs become exhausted, e.g. during chronic retroviral infections. A prominent T cell exhaustion marker is programmed cell death protein 1 (P
Externí odkaz:
https://doaj.org/article/07bf44f1f89744f19d3159b2913196d8
Autor:
Dongpei Yin, Chen Wang, Yachao Qi, Ya-Chao Wang, Nina Hagemann, Ayan Mohamud Yusuf, Egor Dzyubenko, Britta Kaltwasser, Tobias Tertel, Bernd Giebel, Matthias Gunzer, Aurel Popa-Wagner, Thorsten R. Doeppner, Dirk M. Hermann
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-17 (2023)
Abstract Background The intravenous delivery of adult neural precursor cells (NPC) has shown promising results in enabling cerebroprotection, brain tissue remodeling, and neurological recovery in young, healthy stroke mice. However, the translation o
Externí odkaz:
https://doaj.org/article/d0ea9ce64a144be89ce170a2dbfb73e8
Autor:
Anna Malyshkina, Wibke Bayer, Philip Podschwadt, Lucas Otto, Zehra Karakoese, Kathrin Sutter, Kirsten Bruderek, Baoxiao Wang, Kerry J Lavender, Mario L Santiago, Pia Madeleine Leipe, Carina Elsner, Stefan Esser, Sven Brandau, Matthias Gunzer, Ulf Dittmer
Publikováno v:
PLoS Pathogens, Vol 19, Iss 10, p e1011725 (2023)
Antiretroviral therapy (ART) transformed HIV from a life-threatening disease to a chronic condition. However, eliminating the virus remains an elusive therapy goal. For several decades, Friend virus (FV) infection serves as a murine model to study re
Externí odkaz:
https://doaj.org/article/a81ed88024bb4e859ce8d252a4270370
Autor:
Daniela Mittermüller, Lucas Otto, Zoë Long, Andreas Kraus, Alexander Beer, Anja Hasenberg, Gennadiy Zelinskyy, Jaana Westmeier, Kim J. Hasenkrug, Ulf Dittmer, Matthias Gunzer
Publikováno v:
JCI Insight, Vol 8, Iss 13 (2023)
Antiviral immunity often requires CD8+ cytotoxic T lymphocytes (CTLs) that actively migrate and search for virus-infected targets. Regulatory T cells (Tregs) have been shown to suppress CTL responses, but it is not known whether this is also mediated
Externí odkaz:
https://doaj.org/article/5077790e72564cdc8233a583311a8966
Autor:
Vu Thuy Khanh Le-Trilling, Denise Mennerich, Corinna Schuler, Roman Sakson, Julia K. Lill, Siva Swapna Kasarla, Dominik Kopczynski, Stefan Loroch, Yulia Flores-Martinez, Benjamin Katschinski, Kerstin Wohlgemuth, Matthias Gunzer, Folker Meyer, Prasad Phapale, Ulf Dittmer, Albert Sickmann, Mirko Trilling
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-21 (2022)
Abstract Background The SARS-CoV-2/COVID-19 pandemic has inflicted medical and socioeconomic havoc, and despite the current availability of vaccines and broad implementation of vaccination programs, more easily accessible and cost-effective acute tre
Externí odkaz:
https://doaj.org/article/64f1ee9cf6624323968912e635fb6b3a
Autor:
Floriane Bretheau, Adrian Castellanos-Molina, Dominic Bélanger, Maxime Kusik, Benoit Mailhot, Ana Boisvert, Nicolas Vallières, Martine Lessard, Matthias Gunzer, Xiaoyu Liu, Éric Boilard, Ning Quan, Steve Lacroix
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-22 (2022)
The neuroimmune interactions driving secondary degeneration in the injured spinal cord remain elusive. Here, the authors reveal that damaged microglia release IL-1α, resulting in neutrophil infiltration and the loss of mature oligodendrocytes throug
Externí odkaz:
https://doaj.org/article/f3c3924c344a4760823aae7c0f49225c
Autor:
Ina Rohwedder, Lou Martha Wackerbarth, Kristina Heinig, Annamaria Ballweg, Johannes Altstätter, Myriam Ripphahn, Claudia Nussbaum, Melanie Salvermoser, Susanne Bierschenk, Tobias Straub, Matthias Gunzer, Marc Schmidt-Supprian, Thomas Kolben, Christian Schulz, Averil Ma, Barbara Walzog, Matthias Heinig, Markus Sperandio
Publikováno v:
JCI Insight, Vol 8, Iss 4 (2023)
Newborns are at high risk of developing neonatal sepsis, particularly if born prematurely. This has been linked to divergent requirements the immune system has to fulfill during intrauterine compared with extrauterine life. By transcriptomic analysis
Externí odkaz:
https://doaj.org/article/e87a9995376c4685aecbb7a8084026ca
Autor:
Paul R Fortin, Marie-Ève Tremblay, Eric Boilard, Matthias Gunzer, Isabelle Allaeys, Tania Levesque, Louis Flamand, Audrée Laroche, Micaël Carrier, Denis Soulet, Marc Bazin, Nicolas Vallières, Steve Lacroix
Publikováno v:
Lupus Science and Medicine, Vol 9, Iss Suppl 3 (2022)
Externí odkaz:
https://doaj.org/article/071daa2899ca4b979eb7062e5be3f225
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Stroke is primarily a neurodegenerative disease but can also severely impact the functions of other vital organs and deteriorate disease outcomes. A malfunction of the gastrointestinal tract (GIT), commonly observed in stroke patients, is often chara
Externí odkaz:
https://doaj.org/article/790e19feb55b4089a13631a276d83613