Trospium Chloride Transport by Mouse Drug Carriers of the Slc22 and Slc47 Families

Autor: Matthias Gorecki, Simon F. Müller, Regina Leidolf, Joachim Geyer

Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 1
International Journal of Molecular Sciences, Vol 22, Iss 22, p 22 (2021)

Background: The muscarinic receptor antagonist trospium chloride (TCl) is used for pharmacotherapy of the overactive bladder syndrome. TCl is a hydrophilic positively charged drug. Therefore, it has low permeability through biomembranes and requires

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6e4efa7b700f063170bc96d38015fd89
http://europepmc.org/articles/PMC7792585