Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Matthias Germer"'
Publikováno v:
International Journal of Blood Transfusion and Immunohematology. 13:1-8
Aims: To assess potential changes of pharmacological activities of a novel normal immunoglobulin for intravenous administration from pooled normal plasma (IVIG). Methods: We assessed the impact of the SARS-CoV-2 pandemic on the level and activity of
Autor:
Gabriele Niemann, Matthias Germer, Matthias Hauf, Gerhard Poelsler, Juliane Röder, Jörg Schüttrumpf
Publikováno v:
Transfusionsmedizin. 13:18-29
ZusammenfassungDas Prinzip der passiven Immunisierung ist seit dem 19. Jahrhundert bekannt und wird auch bei aktuellen Pandemien als Ansatz zur Prophylaxe und Therapie eingesetzt. Der Schutz wird hierbei übertragen durch Blut, Serum oder Plasma, wel
Autor:
Carolin Schmidt, Sabrina Weißmüller, Fabian Bohländer, Matthias Germer, Martin König, Alexander Staus, Andrea Wartenberg-Demand, Corina C. Heinz, Jörg Schüttrumpf
Publikováno v:
Biomedicines, Vol 9, Iss 7, p 817 (2021)
Activation of the complement system is important for efficient clearance of a wide variety of pathogens via opsonophagocytosis, or by direct lysis via complement-dependent cytotoxicity (CDC). However, in severe infections dysregulation of the complem
Externí odkaz:
https://doaj.org/article/afe8d97594c240b3b7173a1f9f609568
Autor:
Stephan Schwers, Julia Mueller, Peter Turecek, Nikolaus B Binder, Matthias Germer, François Depasse, Björn Hermes, Thomas Dr. Wissel
Publikováno v:
Journal of Thrombosis and Haemostasis. 19:2907-2917
Thrombin is the pivotal enzyme in the biochemistry of secondary hemostasis crucial to maintaining homeostasis of hemostasis. In contrast to routine coagulation tests (PT or aPTT) or procoagulant or anticoagulant factor assays (e.g. fibrinogen, factor
Autor:
François Depasse, Peter Turecek, Thomas Dr. Wissel, Julia Mueller, Björn Hermes, Matthias Germer, Nikolaus B Binder, Stephan Schwers
Publikováno v:
Journal of Thrombosis and Haemostasis. 19:2918-2929
Determining patient's coagulation profile, i.e. detecting a bleeding tendency or the opposite, a thrombotic risk, is crucial for clinicians in many situations. Routine coagulation assays and even more specialized tests may not allow a relevant charac
Autor:
Peter Herbener, Kurt Schönfeld, Martin König, Matthias Germer, Jude M Przyborski, Katrin Bernöster, Jörg Schüttrumpf
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195823 (2018)
An increasing number of monoclonal antibodies and derivatives such as antibody-drug conjugates (ADC) are of the IgG1 and IgG4 isotype with distinct structural and functional properties. In cases where antibody-mediated cytotoxicity is not desired, Ig
Externí odkaz:
https://doaj.org/article/5cd5401408894dbc9333986fdcb6d1d0
Autor:
Martin König, Jörg Schüttrumpf, Andrea Wartenberg-Demand, Matthias Germer, Fabian Bohländer, Sabrina Weißmüller, Alexander Staus, Corina C Heinz, Carolin Schmidt
Publikováno v:
Biomedicines
Biomedicines, Vol 9, Iss 817, p 817 (2021)
Volume 9
Issue 7
Biomedicines, Vol 9, Iss 817, p 817 (2021)
Volume 9
Issue 7
Activation of the complement system is important for efficient clearance of a wide variety of pathogens via opsonophagocytosis, or by direct lysis via complement-dependent cytotoxicity (CDC). However, in severe infections dysregulation of the complem
Publikováno v:
Annals of Transplantation. 21:558-564
BACKGROUND Cytomegalovirus hyperimmunoglobulin (CMV-HIG) preparations reduce mortality after solid organ transplantation. Polyspecific intravenous immunoglobulin (IVIg) products are also used prophylactically by some centers. Since direct comparative
Autor:
Matthias Germer, Jörg Schüttrumpf
Publikováno v:
Drug Discovery and Evaluation: Methods in Clinical Pharmacology ISBN: 9783319566375
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c55ebfa7d86167cea27425bbbdd62ee0
https://doi.org/10.1007/978-3-319-56637-5_34-1
https://doi.org/10.1007/978-3-319-56637-5_34-1
Autor:
Katrin Bernöster, Martin König, Matthias Germer, Kurt Schönfeld, Jude M. Przyborski, Jörg Schüttrumpf, Peter Herbener
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195823 (2018)
PLoS ONE
PLoS ONE
An increasing number of monoclonal antibodies and derivatives such as antibody-drug conjugates (ADC) are of the IgG1 and IgG4 isotype with distinct structural and functional properties. In cases where antibody-mediated cytotoxicity is not desired, Ig