Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Matthias Fahrner"'
Autor:
Evgeniya Petrova, Jesús María López-Gay, Matthias Fahrner, Florent Leturcq, Jean-Pierre de Villartay, Claire Barbieux, Patrick Gonschorek, Lam C. Tsoi, Johann E. Gudjonsson, Oliver Schilling, Alain Hovnanian
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-24 (2024)
Abstract Netherton syndrome (NS) is a rare skin disease caused by loss-of-function mutations in the serine peptidase inhibitor Kazal type 5 (SPINK5) gene. Disease severity and the lack of efficacious treatments call for a better understanding of NS m
Externí odkaz:
https://doaj.org/article/a4b9cbf4d219401da0ec2c2e31fec3de
Autor:
Klemens Fröhlich, Eva Brombacher, Matthias Fahrner, Daniel Vogele, Lucas Kook, Niko Pinter, Peter Bronsert, Sylvia Timme-Bronsert, Alexander Schmidt, Katja Bärenfaller, Clemens Kreutz, Oliver Schilling
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Data independent acquisition (DIA) has been gaining momentum in clinical proteomics. Here, the authors create a benchmark dataset comprising inter-patient heterogeneity to compare popular DIA data analysis workflows for identifying differentially abu
Externí odkaz:
https://doaj.org/article/17f2eb2214c94026859e0c88b1eb7fa8
Autor:
Janina Werner, Patrick Bernhard, Miguel Cosenza-Contreras, Niko Pinter, Matthias Fahrner, Prama Pallavi, Johannes Eberhard, Peter Bronsert, Felix Rückert, Oliver Schilling
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 36, Iss , Pp 100871- (2023)
Pancreatic ductal adenocarcinoma (PDAC) represents one of the most aggressive and lethal malignancies worldwide with an urgent need for new diagnostic and therapeutic strategies. One major risk factor for PDAC is the pre-indication of chronic pancrea
Externí odkaz:
https://doaj.org/article/4139db3688414143995d15f3aedeeb40
Autor:
Saskia Hiltemann, Helena Rasche, Simon Gladman, Hans-Rudolf Hotz, Delphine Larivière, Daniel Blankenberg, Pratik D Jagtap, Thomas Wollmann, Anthony Bretaudeau, Nadia Goué, Timothy J Griffin, Coline Royaux, Yvan Le Bras, Subina Mehta, Anna Syme, Frederik Coppens, Bert Droesbeke, Nicola Soranzo, Wendi Bacon, Fotis Psomopoulos, Cristóbal Gallardo-Alba, John Davis, Melanie Christine Föll, Matthias Fahrner, Maria A Doyle, Beatriz Serrano-Solano, Anne Claire Fouilloux, Peter van Heusden, Wolfgang Maier, Dave Clements, Florian Heyl, Galaxy Training Network, Björn Grüning, Bérénice Batut
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 1, p e1010752 (2023)
There is an ongoing explosion of scientific datasets being generated, brought on by recent technological advances in many areas of the natural sciences. As a result, the life sciences have become increasingly computational in nature, and bioinformati
Externí odkaz:
https://doaj.org/article/418bd96910b049ef9a470281072747d4
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 12, Pp 1240-1251 (2021)
Colorectal adenocarcinomas (CRC) are one of the most commonly diagnosed tumors worldwide. Colorectal adenocarcinomas primarily metastasize into the liver and (less often) into the peritoneum. Patients suffering from CRC-liver metastasis (CRC-LM) typi
Externí odkaz:
https://doaj.org/article/eb23dc4c5c944ebab5bfba4453dc93a1
Autor:
Hannah Maria Baumert, Eric Metzger, Matthias Fahrner, Julie George, Roman K. Thomas, Oliver Schilling, Roland Schüle
Publikováno v:
Cancer Cell International, Vol 20, Iss 1, Pp 1-13 (2020)
Abstract Background Lung cancer is the leading cause of cancer related death worldwide. Over the past 15 years no major improvement of survival rates could be accomplished. The recently discovered histone methyltransferase KMT9 that acts as epigeneti
Externí odkaz:
https://doaj.org/article/18690fb746304b5f9a4a208fa7e2a7dc
Autor:
Beatriz Serrano-Solano, Melanie C Föll, Cristóbal Gallardo-Alba, Anika Erxleben, Helena Rasche, Saskia Hiltemann, Matthias Fahrner, Mark J Dunning, Marcel H Schulz, Beáta Scholtz, Dave Clements, Anton Nekrutenko, Bérénice Batut, Björn A Grüning
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 5, p e1008923 (2021)
The COVID-19 pandemic is shifting teaching to an online setting all over the world. The Galaxy framework facilitates the online learning process and makes it accessible by providing a library of high-quality community-curated training materials, enab
Externí odkaz:
https://doaj.org/article/2203f8fac2ff4349a06b32591ebcd459
Autor:
Melanie Christine Föll, Matthias Fahrner, Victor Oginga Oria, Markus Kühs, Martin Lothar Biniossek, Martin Werner, Peter Bronsert, Oliver Schilling
Publikováno v:
Clinical Proteomics, Vol 15, Iss 1, Pp 1-15 (2018)
Abstract Background Proteomic analyses of clinical specimens often rely on human tissues preserved through formalin-fixation and paraffin embedding (FFPE). Minimal sample consumption is the key to preserve the integrity of pathological archives but a
Externí odkaz:
https://doaj.org/article/e673d58ff4b7477cba97ad7ebfd552f3
Publikováno v:
Proteomes, Vol 9, Iss 2, p 26 (2021)
Liquid chromatography-tandem mass spectrometry (LC-MS/MS) has become the most commonly used technique in explorative proteomic research. A variety of open-source tools for peptide-spectrum matching have become available. Most analyses of explorative
Externí odkaz:
https://doaj.org/article/bef804db7f3c420a9bfbe3cf3e6296b9
Autor:
Janina Werner, Patrick Bernhard, Miguel Cosenza-Contreras, Niko Pinter, Matthias Fahrner, Prama Pallavi, Johannes Eberhard, Peter Bronsert, Felix Rückert, Oliver Schilling
Publikováno v:
Neoplasia (New York, N.Y.). 36
Pancreatic ductal adenocarcinoma (PDAC) represents one of the most aggressive and lethal malignancies worldwide with an urgent need for new diagnostic and therapeutic strategies. One major risk factor for PDAC is the pre-indication of chronic pancrea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6adbaf7eab476f8bab19de5b42fb7677
https://pubmed.ncbi.nlm.nih.gov/36610378
https://pubmed.ncbi.nlm.nih.gov/36610378