Zobrazeno 1 - 10 of 17 pro vyhledávání: '"Matthias Eggel"'
1
Akademický článek
Is selecting better than modifying? An investigation of arguments against germline gene editing as compared to preimplantation genetic diagnosis
Autor: Alix Lenia v. Hammerstein, Matthias Eggel, Nikola Biller-Andorno
Publikováno v: BMC Medical Ethics, Vol 20, Iss 1, Pp 1-13 (2019)
Abstract Background Recent scientific advances in the field of gene editing have led to a renewed discussion on the moral acceptability of human germline modifications. Gene editing methods can be used on human embryos and gametes in order to change
Externí odkaz: https://doaj.org/article/fb0fad82a71e496eb8985b65e997c960
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2
Akademický článek
From Mice to Monkeys? Beyond Orthodox Approaches to the Ethics of Animal Model Choice
Autor: Rebecca L. Walker, Matthias Eggel
Publikováno v: Animals, Vol 10, Iss 1, p 77 (2020)
Recent developments in genome editing tools, along with limits in the translational potential of rodent models of human disease, have spurred renewed biomedical research interest in large mammals like nonhuman primates, pigs, and dogs. Such scientifi
Externí odkaz: https://doaj.org/article/6b03b51e92314b4caec9c63aa8ed97f2
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3
Akademický článek
No Pain, No Gain? In Defence of Genetically Disenhancing (Most) Research Animals
Autor: Katrien Devolder, Matthias Eggel
Publikováno v: Animals, Vol 9, Iss 4, p 154 (2019)
Every year, around 12 million animals are used for the purpose of scientific research in the European Union alone. The procedures performed on them often cause significant pain and suffering. Despite regulations aimed at reducing this suffering, we c
Externí odkaz: https://doaj.org/article/54bfc67e5ea54374a85b6cd78e464236
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4
Akademický článek
Necessary, but Not Sufficient. The Benefit Concept in the Project Evaluation of Animal Research in the Context of Directive 2010/63/EU
Autor: Matthias Eggel, Herwig Grimm
Publikováno v: Animals, Vol 8, Iss 3, p 34 (2018)
Directive 2010/63/EU (henceforth “Directive”) on the protection of animals used for scientific purposes mandates that every project proposal in EU member states involving procedures on living non-human vertebrates and cephalopods has to be approv
Externí odkaz: https://doaj.org/article/3be44bb918b34ee3b2523243c638ebd3
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5
Akademický článek
The Road to Hell Is Paved with Good Intentions: Why Harm–Benefit Analysis and Its Emphasis on Practical Benefit Jeopardizes the Credibility of Research
Autor: Herwig Grimm, Matthias Eggel, Anna Deplazes-Zemp, Nikola Biller-Andorno
Publikováno v: Animals, Vol 7, Iss 9, p 70 (2017)
It is our concern that European Union Directive 2010/63/EU with its current project evaluation of animal research in the form of a harm–benefit analysis may lead to an erosion of the credibility of research. The HBA assesses whether the inflicted h
Externí odkaz: https://doaj.org/article/7743aefe125546f6a5055a8dec633a0d
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8
Internal consistency and compatibility of the 3Rs and 3Vs principles for project evaluation of animal research
Autor: Matthias Eggel, Hanno Würbel
Publikováno v: Laboratory Animals
Eggel, Matthias; Würbel, Hanno (2020). Internal consistency and compatibility of the 3Rs and 3Vs principles for project evaluation of animal research. Laboratory animals, 55(3), pp. 233-243. Sage Publications 10.1177/0023677220968583
Using animals for research raises ethical concerns that are addressed in project evaluation by weighing expected harm to animals against expected benefit to society. A harm–benefit analysis (HBA) relies on two preconditions: (a) the study protocol
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31e102f2f2356f4ccb8b2f8543d22ad0
https://doi.org/10.5167/uzh-196871
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9
From Mice to Monkeys? Beyond Orthodox Approaches to the Ethics of Animal Model Choice
Autor: Matthias Eggel, Rebecca L. Walker
Publikováno v: Animals, Vol 10, Iss 1, p 77 (2020)
Animals : an Open Access Journal from MDPI
Animals
Volume 10
Issue 1
Recent developments in genome editing tools, along with limits in the translational potential of rodent models of human disease, have spurred renewed biomedical research interest in large mammals like nonhuman primates, pigs, and dogs. Such scientifi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af77d968f1b2a7004fcf2e4ae3d959f9
https://www.mdpi.com/2076-2615/10/1/77
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10
Reevaluating Benefits in the Moral Justification of Animal Research: A Comment on 'Necessary Conditions for Morally Responsible Animal Research'
Autor: Matthias Eggel, Carolyn P Neuhaus, Herwig Grimm
In a recent paper in Cambridge Quarterly of Healthcare Ethics on the necessary conditions for morally responsible animal research David DeGrazia and Jeff Sebo claim that the key requirements for morally responsible animal research are (1) an assertio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47b71d4f78943aa52efe8c07ace67f12
https://www.zora.uzh.ch/id/eprint/199663/
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