Zobrazeno 1 - 10
of 521
pro vyhledávání: '"Matthias E. Liechti"'
Autor:
Aaron Klaiber, Yasmin Schmid, Anna M. Becker, Isabelle Straumann, Livio Erne, Alen Jelusic, Jan Thomann, Dino Luethi, Matthias E. Liechti
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Classic psychedelics have regained interest in research and therapy. Despite the long tradition of the human use of mescaline, modern data on its dose-dependent acute effects and pharmacokinetics are lacking. Additionally, its mechanism of a
Externí odkaz:
https://doaj.org/article/dcbd2ff834ac434d90f0dbd91564f91e
Autor:
Patrick Vizeli, Erich Studerus, Friederike Holze, Yasmin Schmid, Patrick C. Dolder, Laura Ley, Isabelle Straumann, Anna M. Becker, Felix Müller, Denis Arikci, Matthias E. Liechti
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract The pharmacodynamic effects of lysergic acid diethylamide (LSD) are diverse and different in different individuals. Effects of other psychoactive substances have been shown to be critically influenced by non-pharmacological factors such as p
Externí odkaz:
https://doaj.org/article/dff35d6d882c495e9ff0f88889429865
Autor:
Nadia R. P. W. Hutten, Conny W. E. M. Quaedflieg, Natasha L. Mason, Eef L. Theunissen, Matthias E. Liechti, Urs Duthaler, Kim P. C. Kuypers, Valerie Bonnelle, Amanda Feilding, Johannes G. Ramaekers
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract The repeated use of small doses of psychedelics (also referred to as “microdosing”) to facilitate benefits in mental health, cognition, and mood is a trending practice. Placebo-controlled studies however have largely failed to demonstrat
Externí odkaz:
https://doaj.org/article/2e3b94844f724d0b8588363b1ebe9d2a
Autor:
Hugo R. Arias, Laura Micheli, Deborah Rudin, Ophelie Bento, Saskia Borsdorf, Clara Ciampi, Philippe Marin, Evgeni Ponimaskin, Dina Manetti, Maria Novella Romanelli, Carla Ghelardini, Matthias E. Liechti, Lorenzo Di Cesare Mannelli
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 116867- (2024)
The aim of this study was to determine the anti-hypersensitivity activity of novel non-hallucinogenic compounds derived from iboga alkaloids (i.e., ibogalogs), including tabernanthalog (TBG), ibogainalog (IBG), and ibogaminalog (DM506), using mouse m
Externí odkaz:
https://doaj.org/article/c642e18ca6d94d9db88979a07890f2b3
Autor:
Odd Martin Vallersnes, Alison M. Dines, David M. Wood, Fridtjof Heyerdahl, Knut Erik Hovda, Christopher Yates, Isabelle Giraudon, Blazena Caganova, Alessandro Ceschi, Miguel Galicia, Evangelia Liakoni, Matthias E. Liechti, Òscar Miró, Roberta Noseda, Per Sverre Persett, Kristiina Põld, Yasmin Schmid, Irene Scholz, Federico Vigorita, Paul I. Dargan
Publikováno v:
International Journal of Emergency Medicine, Vol 16, Iss 1, Pp 1-10 (2023)
Abstract Background Self-discharge is a risk factor for readmission and excess mortality. We assess the rate of self-discharge from the emergency department (ED) among presentations for acute recreational drug toxicity and identify factors associated
Externí odkaz:
https://doaj.org/article/b1b7455f0e2146eea6f92b4713109baa
Autor:
Jan Thomann, Karolina E. Kolaczynska, Oliver V. Stoeckmann, Deborah Rudin, Patrick Vizeli, Marius C. Hoener, Christopher R. Pryce, Franz X. Vollenweider, Matthias E. Liechti, Urs Duthaler
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
In vivo, psilocybin is rapidly dephosphorylated to psilocin which induces psychedelic effects by interacting with the 5-HT2A receptor. Psilocin primarily undergoes glucuronidation or conversion to 4-hydroxyindole-3-acetic acid (4-HIAA). Herein, we in
Externí odkaz:
https://doaj.org/article/4de9dedd97a84c36b079001eb96b0419
Pharmacokinetics of ivermectin metabolites and their activity against Anopheles stephensi mosquitoes
Autor:
Charlotte Kern, Pie Müller, Carlos Chaccour, Matthias E. Liechti, Felix Hammann, Urs Duthaler
Publikováno v:
Malaria Journal, Vol 22, Iss 1, Pp 1-17 (2023)
Abstract Background Ivermectin (22,23-dihydroavermectin B1a: H2B1a) is an endectocide used to treat worm infections and ectoparasites including lice and scabies mites. Furthermore, survival of malaria transmitting Anopheles mosquitoes is strongly dec
Externí odkaz:
https://doaj.org/article/d7ca8cf4767c49129b8d740a887b535c
Autor:
Severin B. Vogt, Laura Ley, Livio Erne, Isabelle Straumann, Anna M. Becker, Aaron Klaiber, Friederike Holze, Anja Vandersmissen, Lorenz Mueller, Urs Duthaler, Deborah Rudin, Dino Luethi, Nimmy Varghese, Anne Eckert, Matthias E. Liechti
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract N,N-dimethyltryptamine (DMT) is distinct among classic serotonergic psychedelics because of its short-lasting effects when administered intravenously. Despite growing interest in the experimental and therapeutic use of intravenous DMT, data
Externí odkaz:
https://doaj.org/article/7139114793b948e18e686627fb06fc22
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
BackgroundThe interest in psychoactive agents for treating mental disorders has gathered a growing body of scientific interest. However, research on the relationship between altered states of consciousness (ASCs) and ketamine’s antidepressant prope
Externí odkaz:
https://doaj.org/article/bc180b0dae34499f8423132056e11d4b
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
IntroductionClassic psychedelics have been shown to exert therapeutic potential for the treatment of various psychiatric disorders, neuropsychiatric diseases, and neuronal damage. Besides their psychopharmacological activity, psychedelics have been r
Externí odkaz:
https://doaj.org/article/f68be9b6ba06439bb89901578f413d6e