Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Matthias Bleeke"'
Autor:
Neels Lennart Aden, Matthias Bleeke, Uwe R. Kordes, Bianka Brunne, Barbara Holstermann, Ronald Biemann, Uta Ceglarek, Armin Soave, Andrea Salzbrunn, Stefan W. Schneider, Kathrein von Kopylow
Publikováno v:
Cells, Vol 12, Iss 3, p 415 (2023)
Human prepubertal testicular tissues are rare, but organ culture conditions to develop a system for human in vitro-spermatogenesis are an essential option for fertility preservation in prepubertal boys subjected to gonadotoxic therapy. To avoid anima
Externí odkaz:
https://doaj.org/article/e88e3ab867be45c8ac0d429d1e6bdee6
Autor:
Katharina Grützediek, Roland Fischer, Gregory Kurio, Lukas Böckelmann, Matthias Bleeke, Robert Ward Hagar, Enver Tahir, Regine Grosse, Marcela Weyhmiller, Gerhard Adam, Peter Bannas, Bjoern P. Schoennagel
Publikováno v:
Journal of Magnetic Resonance Imaging.
Publikováno v:
Pediatric Dermatology. 38:875-878
We report the case of a 4-year-old boy, post-human stem cell transplantation for severe combined immunodeficiency (SCID) due to adenosine deaminase deficiency (ADA), who developed multiple dermatofibrosarcoma protuberans (DFSP). We hypothesize a role
Autor:
Ingo Müller, Wolfram Klapper, Susanne Gröbner, Julia Alten, Pascal Johann, Stefan M. Pfister, Hansjörg Schäfer, Matthias Bleeke, Gunnar Cario, Joseph D. Khoury
Pediatric histiocytic sarcoma (HS) clonally related to anteceding leukemia is a rare malignancy with poor outcome. We performed a molecular characterization of HS and the corresponding leukemia by methylation arrays and whole-exome sequencing and fou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b36ba3668075a21f8f2ddaf25802d97
Autor:
Kerstin Hilt, Bianca Baykan, Holger N. Lode, Alexander Stermann, Angelika Eggert, Tahir Durmus, Alexander Schramm, Matthias Bleeke, Stefan Fest, Silke Weixler, Nicole Huebener, Anja Woehler, Gerhard Gaedicke
Publikováno v:
Molecular Cancer Therapeutics. 8:2392-2401
Neuroblastoma (NB) is a challenging malignancy of the sympathetic nervous tissue characterized by a very poor prognosis. One important marker for NB is the expression of tyrosine hydroxylase (TH), the first-step enzyme of catecholamine biosynthesis.
Autor:
Alexander Stermann, Bianca Baykan, Ines S. Jaeger, Gerhard Gaedicke, Elke Michalsky, Tahir Durmus, Matthias Bleeke, Stefan Fest, Silke Weixler, Anja Woehler, Nicole Huebener, Oliver Hohn, Holger N. Lode, Ana Claudia Zenclussen, Robert Preissner
Publikováno v:
International Journal of Cancer. 125:104-114
The inhibitor of apoptosis protein survivin is highly expressed in neuroblastoma (NB) and survivin-specific T cells were identified in Stage 4 patients. Therefore, we generated a novel survivin minigene DNA vaccine (pUS-high) encoding exclusively for
Autor:
Sven Brandt, Manuela Schmidt, Hans-Peter Mueller, Matthias Bleeke, Diana Seidel, Diana Brackrock, Daniel Reker, Holger N. Lode, Nikolai Siebert, Christiane A. Helm, Nicole Huebener
Publikováno v:
Cancer immunology, immunotherapy : CII. 62(6)
Immunotherapy targeting disialoganglioside GD(2) emerges as an important treatment option for neuroblastoma, a pediatric malignancy characterized by poor outcome. Here, we report the induction of a GD(2)-specific immune response with ganglidiomab, a
Autor:
Rudolf Volkmer, Holger N. Lode, Gerhard Gaedicke, Matthias Bleeke, Nicole Huebener, Burkhart Schraven, Stefan Fest, Christiane Landgraf
Publikováno v:
European journal of cancer (Oxford, England : 1990). 45(16)
The likelihood of identifying peptides of sufficient quality for the development of effective cancer vaccines by screening of phage display libraries is low. Here, we introduce the sequential application of systematic amino acid substitution by SPOT
Autor:
Anne Strandsby, Angelika B. Riemer, Nicole Huebener, Elisabeth Förster-Wald, Holger N. Lode, Christiane Landgraf, Yan Zeng, Elke Michalsky, Ines S. Jaeger, Gerhard Gaedicke, Matthias Bleeke, Erika Jensen-Jarolim, Robert Preissner, Rudolf Volkmer-Engert, Stefan Fest, Silke Weixler
Publikováno v:
Cancer research. 66(21)
Disialoganglioside GD2 is an established target for immunotherapy in neuroblastoma. We tested the hypothesis that active immunization against the glycolipid GD2 using DNA vaccines encoding for cyclic GD2-mimicking decapeptides (i.e., GD2 mimotopes) i
Autor:
Holger N. Lode, Nikolai Siebert, Diana Brackrock, Daniel Reker, Hans-Peter Mueller, Matthias Bleeke, Sven Brandt, Christiane Helm, Diana Seidel, Manuela Schmidt, Nicole Huebener
Publikováno v:
Cancer Research. 73:A28-A28
Purpose: Immunotherapy targeting disialoganglioside GD2 emerges as an important treatment option for neuroblastoma, a pediatric malignancy characterized by poor outcome. Here, we report the generation and characterization of ganglidiomab, a new anti-