Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Matthias Bartenstein"'
Autor:
Tushar D Bhagat, Dagny Von Ahrens, Meelad Dawlaty, Yiyu Zou, Joelle Baddour, Abhinav Achreja, Hongyun Zhao, Lifeng Yang, Brijesh Patel, Changsoo Kwak, Gaurav S Choudhary, Shanisha Gordon-Mitchell, Srinivas Aluri, Sanchari Bhattacharyya, Srabani Sahu, Prafulla Bhagat, Yiting Yu, Matthias Bartenstein, Orsi Giricz, Masako Suzuki, Davendra Sohal, Sonal Gupta, Paola A Guerrero, Surinder Batra, Michael Goggins, Ulrich Steidl, John Greally, Beamon Agarwal, Kith Pradhan, Debabrata Banerjee, Deepak Nagrath, Anirban Maitra, Amit Verma
Publikováno v:
eLife, Vol 8 (2019)
Even though pancreatic ductal adenocarcinoma (PDAC) is associated with fibrotic stroma, the molecular pathways regulating the formation of cancer associated fibroblasts (CAFs) are not well elucidated. An epigenomic analysis of patient-derived and de-
Externí odkaz:
https://doaj.org/article/de3a332d705e4701ab12d60c3c437380
Autor:
Amit Verma, Ulrich Steidl, Kith Pradhan, Laurence E. Burgess, Leonidas C. Platanias, Yiyu Zou, David Chantry, Stefan Gross, Mareli Rodriguez, Mark Munson, Dale Wright, Grant Hogeland, Lance Wollenberg, Suzy Brown, Jennifer Garrus, James Rizzi, Chandan Guha, Yiting Yu, Carolina Schinke, Jacqueline Boultwood, Andrea Pellagatti, Shanisha Gordon-Mitchell, Aditi Shastri, Amer Assal, Sanchari Bhattacharyya, Tushar D. Bhagat, Samira Shahnaz, George Nwankwo, Vineeth Sukrithan, Orsi Giricz, Nandini Ramachandra, Matthias Bartenstein, Ioannis Mantzaris, Shannon L. Winski, Kerry Morrone, Lohith Bachegowda
Knockdown of Angpt1 does not lead to inhibition of leukemic cell viability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54b4c1894cac38e6a965b9d6cd80cf7b
https://doi.org/10.1158/0008-5472.22411319.v1
https://doi.org/10.1158/0008-5472.22411319.v1
Autor:
Amit Verma, Ulrich Steidl, Kith Pradhan, Laurence E. Burgess, Leonidas C. Platanias, Yiyu Zou, David Chantry, Stefan Gross, Mareli Rodriguez, Mark Munson, Dale Wright, Grant Hogeland, Lance Wollenberg, Suzy Brown, Jennifer Garrus, James Rizzi, Chandan Guha, Yiting Yu, Carolina Schinke, Jacqueline Boultwood, Andrea Pellagatti, Shanisha Gordon-Mitchell, Aditi Shastri, Amer Assal, Sanchari Bhattacharyya, Tushar D. Bhagat, Samira Shahnaz, George Nwankwo, Vineeth Sukrithan, Orsi Giricz, Nandini Ramachandra, Matthias Bartenstein, Ioannis Mantzaris, Shannon L. Winski, Kerry Morrone, Lohith Bachegowda
MDS Patient Characteristics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c73a73bca7fedee19f2d4106b89f27f
https://doi.org/10.1158/0008-5472.22411307.v1
https://doi.org/10.1158/0008-5472.22411307.v1
Autor:
Amit Verma, Michael G. Kharas, H. Joachim Deeg, Marc H.G.P. Raaijmakers, Ulrich Steidl, Britta Will, Jacqueline Boultwood, Andrea Pellagatti, Siddhartha Mukherjee, John M. Greally, Jinghang Zhang, Kith Pradhan, Yiting Yu, Konrad Hochedlinger, Peter Aplan, Kira Gritsman, Cecilia Yeung, Amittha Wickrema, Davendra Sohal, Orsi Giricz, Prafulla Bhagat, Robert Lopez, Remi Laurence, Vineeth Sukrithan, Iaonnis Mantzaris, Nandini Ramachandra, Suman Kambhampati, Remco M. Hoogenboezem, Mathijs A. Sanders, A. Mario Marcondes, Elianna Amin, Patrick Tivnan, Gaurav S. Choudhary, Dagny Von Ahrens, A. Trevor Barlowe, Matthias Bartenstein, Si Chen, Tushar D. Bhagat
Supp Table 1: MDS Patient Disease Characteristics Supp Table 2: Pathways affected by hypermethylation in MDS stroma Supp Table 3: Genes that are methylated and underexpressed in MDS stroma Supp Table 4. MDS patient characteristics for primary MSC sam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dae0ab1066c8473f458390b001954c2
https://doi.org/10.1158/0008-5472.22414418.v1
https://doi.org/10.1158/0008-5472.22414418.v1
Autor:
Amit Verma, Ulrich Steidl, Kith Pradhan, Laurence E. Burgess, Leonidas C. Platanias, Yiyu Zou, David Chantry, Stefan Gross, Mareli Rodriguez, Mark Munson, Dale Wright, Grant Hogeland, Lance Wollenberg, Suzy Brown, Jennifer Garrus, James Rizzi, Chandan Guha, Yiting Yu, Carolina Schinke, Jacqueline Boultwood, Andrea Pellagatti, Shanisha Gordon-Mitchell, Aditi Shastri, Amer Assal, Sanchari Bhattacharyya, Tushar D. Bhagat, Samira Shahnaz, George Nwankwo, Vineeth Sukrithan, Orsi Giricz, Nandini Ramachandra, Matthias Bartenstein, Ioannis Mantzaris, Shannon L. Winski, Kerry Morrone, Lohith Bachegowda
Proposed model of efficacy of dual inhibitor of Tie2 and p38 MAPK in MDS and AML
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8299ab0d2dd7a5ca493862f61d3e84ee
https://doi.org/10.1158/0008-5472.22411316.v1
https://doi.org/10.1158/0008-5472.22411316.v1
Autor:
Amit Verma, Michael G. Kharas, H. Joachim Deeg, Marc H.G.P. Raaijmakers, Ulrich Steidl, Britta Will, Jacqueline Boultwood, Andrea Pellagatti, Siddhartha Mukherjee, John M. Greally, Jinghang Zhang, Kith Pradhan, Yiting Yu, Konrad Hochedlinger, Peter Aplan, Kira Gritsman, Cecilia Yeung, Amittha Wickrema, Davendra Sohal, Orsi Giricz, Prafulla Bhagat, Robert Lopez, Remi Laurence, Vineeth Sukrithan, Iaonnis Mantzaris, Nandini Ramachandra, Suman Kambhampati, Remco M. Hoogenboezem, Mathijs A. Sanders, A. Mario Marcondes, Elianna Amin, Patrick Tivnan, Gaurav S. Choudhary, Dagny Von Ahrens, A. Trevor Barlowe, Matthias Bartenstein, Si Chen, Tushar D. Bhagat
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7088e12509540b55682090ae288f6768
https://doi.org/10.1158/0008-5472.22414421
https://doi.org/10.1158/0008-5472.22414421
Autor:
Amit Verma, Ulrich Steidl, Kith Pradhan, Laurence E. Burgess, Leonidas C. Platanias, Yiyu Zou, David Chantry, Stefan Gross, Mareli Rodriguez, Mark Munson, Dale Wright, Grant Hogeland, Lance Wollenberg, Suzy Brown, Jennifer Garrus, James Rizzi, Chandan Guha, Yiting Yu, Carolina Schinke, Jacqueline Boultwood, Andrea Pellagatti, Shanisha Gordon-Mitchell, Aditi Shastri, Amer Assal, Sanchari Bhattacharyya, Tushar D. Bhagat, Samira Shahnaz, George Nwankwo, Vineeth Sukrithan, Orsi Giricz, Nandini Ramachandra, Matthias Bartenstein, Ioannis Mantzaris, Shannon L. Winski, Kerry Morrone, Lohith Bachegowda
Supp Fig 1-3 Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ce43155edc21e008218ff125ff0c3c7
https://doi.org/10.1158/0008-5472.22411313.v1
https://doi.org/10.1158/0008-5472.22411313.v1
Autor:
Amit Verma, Michael G. Kharas, H. Joachim Deeg, Marc H.G.P. Raaijmakers, Ulrich Steidl, Britta Will, Jacqueline Boultwood, Andrea Pellagatti, Siddhartha Mukherjee, John M. Greally, Jinghang Zhang, Kith Pradhan, Yiting Yu, Konrad Hochedlinger, Peter Aplan, Kira Gritsman, Cecilia Yeung, Amittha Wickrema, Davendra Sohal, Orsi Giricz, Prafulla Bhagat, Robert Lopez, Remi Laurence, Vineeth Sukrithan, Iaonnis Mantzaris, Nandini Ramachandra, Suman Kambhampati, Remco M. Hoogenboezem, Mathijs A. Sanders, A. Mario Marcondes, Elianna Amin, Patrick Tivnan, Gaurav S. Choudhary, Dagny Von Ahrens, A. Trevor Barlowe, Matthias Bartenstein, Si Chen, Tushar D. Bhagat
The bone marrow microenvironment influences malignant hematopoiesis, but how it promotes leukemogenesis has not been elucidated. In addition, the role of the bone marrow stroma in regulating clinical responses to DNA methyltransferase inhibitors (DNM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f33ca2e7ce5f82dc31f12f52089be88
https://doi.org/10.1158/0008-5472.c.6508973.v1
https://doi.org/10.1158/0008-5472.c.6508973.v1
Autor:
Amit Verma, Ulrich Steidl, Kith Pradhan, Laurence E. Burgess, Leonidas C. Platanias, Yiyu Zou, David Chantry, Stefan Gross, Mareli Rodriguez, Mark Munson, Dale Wright, Grant Hogeland, Lance Wollenberg, Suzy Brown, Jennifer Garrus, James Rizzi, Chandan Guha, Yiting Yu, Carolina Schinke, Jacqueline Boultwood, Andrea Pellagatti, Shanisha Gordon-Mitchell, Aditi Shastri, Amer Assal, Sanchari Bhattacharyya, Tushar D. Bhagat, Samira Shahnaz, George Nwankwo, Vineeth Sukrithan, Orsi Giricz, Nandini Ramachandra, Matthias Bartenstein, Ioannis Mantzaris, Shannon L. Winski, Kerry Morrone, Lohith Bachegowda
Gene sets differentially expressed in Angpt-1 high MDS samples
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a5e1cc736dfdff1bbbe46fd6f8edf15
https://doi.org/10.1158/0008-5472.22411310
https://doi.org/10.1158/0008-5472.22411310
Autor:
Amit Verma, Michael G. Kharas, H. Joachim Deeg, Marc H.G.P. Raaijmakers, Ulrich Steidl, Britta Will, Jacqueline Boultwood, Andrea Pellagatti, Siddhartha Mukherjee, John M. Greally, Jinghang Zhang, Kith Pradhan, Yiting Yu, Konrad Hochedlinger, Peter Aplan, Kira Gritsman, Cecilia Yeung, Amittha Wickrema, Davendra Sohal, Orsi Giricz, Prafulla Bhagat, Robert Lopez, Remi Laurence, Vineeth Sukrithan, Iaonnis Mantzaris, Nandini Ramachandra, Suman Kambhampati, Remco M. Hoogenboezem, Mathijs A. Sanders, A. Mario Marcondes, Elianna Amin, Patrick Tivnan, Gaurav S. Choudhary, Dagny Von Ahrens, A. Trevor Barlowe, Matthias Bartenstein, Si Chen, Tushar D. Bhagat
Supp Fig 1 : SFRP1 methylation with coculture Supp Fig 2 : Validation of methylation changes with stroma and leukemic cell coculture Supp Fig 3: FRZB upregulation in MDS stroma after 5-Azacytidine treatment SuppFig 4: FRZB knockdown leads to partial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0489f392c2b7fdad35acf602880e9cba
https://doi.org/10.1158/0008-5472.22414424.v1
https://doi.org/10.1158/0008-5472.22414424.v1