Zobrazeno 1 - 10
of 334
pro vyhledávání: '"Matthias, von Herrath"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Type 1 diabetes (T1D) is caused by an autoimmune process which culminates in the destruction of insulin-producing beta cells in the pancreas. It is widely believed that a complex and multifactorial interplay between genetic and environmental factors,
Externí odkaz:
https://doaj.org/article/6d2b873aa93243fa84934369d866af22
Autor:
Tomi Suomi, Inna Starskaia, Ubaid Ullah Kalim, Omid Rasool, Maria K. Jaakkola, Toni Grönroos, Tommi Välikangas, Caroline Brorsson, Gianluca Mazzoni, Sylvaine Bruggraber, Lut Overbergh, David Dunger, Mark Peakman, Piotr Chmura, Søren Brunak, Anke M. Schulte, Chantal Mathieu, Mikael Knip, Riitta Lahesmaa, Laura L. Elo, Pieter Gillard, Kristina Casteels, Lutgart Overbergh, Chris Wallace, Mark Evans, Ajay Thankamony, Emile Hendriks, Loredana Marcoveccchio, Timothy Tree, Noel G. Morgan, Sarah Richardson, John A. Todd, Linda Wicker, Adrian Mander, Colin Dayan, Mohammad Alhadj Ali, Thomas Pieber, Decio L. Eizirik, Myriam Cnop, Flemming Pociot, Jesper Johannesen, Peter Rossing, Cristina Legido Quigley, Roberto Mallone, Raphael Scharfmann, Christian Boitard, Timo Otonkoski, Riitta Veijola, Matej Oresic, Jorma Toppari, Thomas Danne, Anette G. Ziegler, Peter Achenbach, Teresa Rodriguez-Calvo, Michele Solimena, Ezio E. Bonifacio, Stephan Speier, Reinhard Holl, Francesco Dotta, Francesco Chiarelli, Piero Marchetti, Emanuele Bosi, Stefano Cianfarani, Paolo Ciampalini, Carine De Beaufort, Knut Dahl-Jørgensen, Torild Skrivarhaug, Geir Joner, Lars Krogvold, Przemka Jarosz-Chobot, Tadej Battelino, Bernard Thorens, Martin Gotthardt, Bart O. Roep, Tanja Nikolic, Arnaud Zaldumbide, Ake Lernmark, Marcus Lundgren, Guillaume Costacalde, Thorsten Strube, Almut Nitsche, Jose Vela, Matthias Von Herrath, Johnna Wesley, Antonella Napolitano-Rosen, Melissa Thomas, Nanette Schloot, Allison Goldfine, Frank Waldron-Lynch, Jill Kompa, Aruna Vedala, Nicole Hartmann, Gwenaelle Nicolas, Jean van Rampelbergh, Nicolas Bovy, Sanjoy Dutta, Jeannette Soderberg, Simi Ahmed, Frank Martin, Esther Latres, Gina Agiostratidou, Anne Koralova, Ruben Willemsen, Anne Smith, Binu Anand, Vipan Datta, Vijith Puthi, Sagen Zac-Varghese, Renuka Dias, Premkumar Sundaram, Bijay Vaidya, Catherine Patterson, Katharine Owen, Barbara Piel, Simon Heller, Tabitha Randell, Tasso Gazis, Elise Bismuth Reismen, Jean-Claude Carel, Jean-Pierre Riveline, Jean-Francoise Gautier, Fabrizion Andreelli, Florence Travert, Emmanuel Cosson, Alfred Penfornis, Catherine Petit, Bruno Feve, Nadine Lucidarme, Jean-Paul Beressi, Catherina Ajzenman, Alina Radu, Stephanie Greteau-Hamoumou, Cecile Bibal, Thomas Meissner, Bettina Heidtmann, Sonia Toni, Birgit Rami-Merhar, Bart Eeckhout, Bernard Peene, N. Vantongerloo, Toon Maes, Leen Gommers
Publikováno v:
EBioMedicine, Vol 92, Iss , Pp 104625- (2023)
Summary: Background: Type 1 diabetes is a complex heterogenous autoimmune disease without therapeutic interventions available to prevent or reverse the disease. This study aimed to identify transcriptional changes associated with the disease progress
Externí odkaz:
https://doaj.org/article/2c41bdea112542e1901b5cf0742fc2e4
Autor:
Negar Moradian, Hans D. Ochs, Constantine Sedikies, Michael R. Hamblin, Carlos A. Camargo, J. Alfredo Martinez, Jacob D. Biamonte, Mohammad Abdollahi, Pedro J. Torres, Juan J. Nieto, Shuji Ogino, John F. Seymour, Ajith Abraham, Valentina Cauda, Sudhir Gupta, Seeram Ramakrishna, Frank W. Sellke, Armin Sorooshian, A. Wallace Hayes, Maria Martinez-Urbistondo, Manoj Gupta, Leila Azadbakht, Ahmad Esmaillzadeh, Roya Kelishadi, Alireza Esteghamati, Zahra Emam-Djomeh, Reza Majdzadeh, Partha Palit, Hamid Badali, Idupulapati Rao, Ali Akbar Saboury, L. Jagan Mohan Rao, Hamid Ahmadieh, Ali Montazeri, Gian Paolo Fadini, Daniel Pauly, Sabu Thomas, Ali A. Moosavi-Movahed, Asghar Aghamohammadi, Mehrdad Behmanesh, Vafa Rahimi-Movaghar, Saeid Ghavami, Roxana Mehran, Lucina Q. Uddin, Matthias Von Herrath, Bahram Mobasher, Nima Rezaei
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-7 (2020)
Abstract The COVID-19 pandemic has become the leading societal concern. The pandemic has shown that the public health concern is not only a medical problem, but also affects society as a whole; so, it has also become the leading scientific concern. W
Externí odkaz:
https://doaj.org/article/120cd09ce7fa494abb4748f3b788a015
Autor:
John Sidney, Jose Luis Vela, Dave Friedrich, Ravi Kolla, Matthias von Herrath, Johnna D. Wesley, Alessandro Sette
Publikováno v:
BMC Immunology, Vol 19, Iss 1, Pp 1-10 (2018)
Abstract Background Type 1 diabetes (T1D) is thought to be an autoimmune disease driven by anti-islet antigen responses and mediated by T-cells. Recent published data suggests that T-cell reactivity to modified peptides, effectively neoantigens, may
Externí odkaz:
https://doaj.org/article/3652a2db71974c839a66d26a3602d43e
Autor:
Cate Speake, Henry T. Bahnson, Johnna D. Wesley, Nikole Perdue, David Friedrich, Minh N. Pham, Erinn Lanxon-Cookson, William W. Kwok, Birgit Sehested Hansen, Matthias von Herrath, Carla J. Greenbaum
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Immune analytes have been widely tested in efforts to understand the heterogeneity of disease progression, risk, and therapeutic responses in type 1 diabetes (T1D). The future clinical utility of such analytes as biomarkers depends on their technical
Externí odkaz:
https://doaj.org/article/f9e809a44be54d9197a31771f3c2ac83
Autor:
Niloufar Yazdanpanah, Filip Dochy, Gary L. Darmstadt, Godefridus J. Peters, Abraham Tsitlakidis, Elias C. Aifantis, Artemi Cerda, Elisabetta Comini, Serge Brand, Manoj Gupta, Bruce D. Cheson, Sabu Thomas, Michael Tanzer, Ralf Weiskirchen, Federico Bella, Seyed-Mohammad Fereshtehnejad, Konstantina Nikita, Imran Ali, Koichi Kato, Alessandro Poggi, Ernest Chua Kian Jon, Idupulapati M. Rao, Xiaoming Tao, Ji-Huan He, Lingamallu Jagan Mohan Rao, Alexander Leemans, Alessio Pomponio, Alfredo Martínez Hernandez, Hamid Ahmadieh, Mohammad Ali Sahraian, Roya Kelishadi, Visith Thongboonkerd, Seema Bahinipati, Masakazu Toi, Matthias von Herrath, Frank Sellke, Steven Sherwood, George Perry, Juan J. Nieto, Sudhir Gupta, Tommaso Dorigo, Bahram Mobasher, Hans D. Ochs, Nima Rezaei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81f53ab518cf09054613095e7e632e41
https://hdl.handle.net/11589/247840
https://hdl.handle.net/11589/247840
Autor:
Estefania Quesada-Masachs, Samuel Zilberman, Sakthi Rajendran, Tiffany Chu, Sara McArdle, William B. Kiosses, Jae-Hyun M. Lee, Burcak Yesildag, Mehdi A. Benkahla, Agnieszka Pawlowska, Madeleine Graef, Susanne Pfeiffer, Zbigniew Mikulski, Matthias von Herrath
Publikováno v:
Diabetologia. 65:387-401
We aimed to characterise and quantify the expression of HLA class II (HLA-II) in human pancreatic tissue sections and to analyse its induction in human islets.We immunostained human pancreatic tissue sections from non-diabetic (n = 5), autoantibody p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c2e4aa8d23ba15d37139e447186f4b6
https://doi.org/10.1007/s00125-021-05619-9
https://doi.org/10.1007/s00125-021-05619-9
Autor:
Ken Coppieters, Matthias von Herrath
Publikováno v:
Frontiers in Medicine, Vol 5 (2018)
Optimized insulin therapies, increased use of continuous glucose monitoring/insulin pumps and most importantly the arrival of reliable closed loop systems will undeniably lead to a reduction in the burden of complications that arise from type 1 diabe
Externí odkaz:
https://doaj.org/article/8bf0c33b77e24b4f98a2bda95bde50f7
Publikováno v:
Diabetologia
Graphical abstract In type 1 diabetes, insulin remains the mature therapeutic cornerstone; yet, the increasing number of individuals developing type 1 diabetes (predominantly children and adolescents) still face severe complications. Fortunately, our
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cefb15c480ded6699ae709284a60483
http://europepmc.org/articles/PMC8012324
http://europepmc.org/articles/PMC8012324
Autor:
Lars Krogvold, Natalie Amirian, Teresa Rodriguez-Calvo, Knut Dahl-Jørgensen, Matthias von Herrath
Publikováno v:
Diabetes 70, 752-758 (2021)
In type 1 diabetes (T1D), a lifelong autoimmune disease, T cells infiltrate the islets and the exocrine pancreas in high numbers. CD8+ T cells are the main cell type found in the insulitic lesion, and CD8+ T cells reactive against β-cell antigens ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91c63258e808120142a4cfbe796a90c7
https://doi.org/10.2337/db20-0908
https://doi.org/10.2337/db20-0908