Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Matthias, Tenbusch"'
Autor:
Jana Fuchs, Julian Hübner, Anna Schmidt, Pascal Irrgang, Clara Maier, Ana Vieira Antão, Friederike Oltmanns, Christian Thirion, Dennis Lapuente, Matthias Tenbusch
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-15 (2024)
Abstract Respiratory syncytial virus (RSV) is the leading cause of severe lower respiratory tract infections in infants and toddlers. Since natural infections do not induce persistent immunity, there is the need of vaccines providing long-term protec
Externí odkaz:
https://doaj.org/article/f6ca5b83ec59445c983e3d1cc0012d15
Autor:
Andrew Muir, Basudev Paudyal, Selma Schmidt, Ehsan Sedaghat-Rostami, Soumendu Chakravarti, Sonia Villanueva-Hernández, Katy Moffat, Noemi Polo, Nicos Angelopoulos, Anna Schmidt, Matthias Tenbusch, Graham Freimanis, Wilhelm Gerner, Arianne C Richard, Elma Tchilian
Publikováno v:
PLoS Pathogens, Vol 20, Iss 7, p e1011910 (2024)
The pig is a natural host for influenza viruses and integrally involved in virus evolution through interspecies transmissions between humans and swine. Swine have many physiological, anatomical, and immunological similarities to humans, and are an ex
Externí odkaz:
https://doaj.org/article/bc240ee05da74cccb8d07006bf4911f8
Autor:
Ana Vieira Antão, Friederike Oltmanns, Anna Schmidt, Vera Viherlehto, Pascal Irrgang, Marie-Anne Rameix-Welti, Wibke Bayer, Dennis Lapuente, Matthias Tenbusch
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Influenza A Virus (IAV) and Respiratory Syncytial Virus (RSV) are both responsible for millions of severe respiratory tract infections every year worldwide. Effective vaccines able to prevent transmission and severe disease, are important measures to
Externí odkaz:
https://doaj.org/article/9564d989b533458a88eedb4bdbf7cc63
Autor:
Claudia Gravekamp, Benjamin Frey, Carol Imanuel Geppert, Udo Gaipl, Michael Rückert, Anna Schmidt, Friederike Oltmanns, Ana Vieira Antão, Pascal Irrgang, Vera Viherlehto, Leticia Jörg, Jannik T Wagner, Ann-Sophie Flohr, Wibke Bayer, Matthias Tenbusch, Dennis Lapuente
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 3 (2024)
Background Generally, early-stage breast cancer has a good prognosis. However, if it spreads systemically, especially with pulmonary involvement, prospects worsen dramatically. Importantly, tumor-infiltrating T cells contribute to tumor control, part
Externí odkaz:
https://doaj.org/article/2ff11b2291004e55aa0c500cd8410a20
Autor:
Natascha Ingrid Drude, Lorena Martinez-Gamboa, Meggie Danziger, Anja Collazo, Silke Kniffert, Janine Wiebach, Gustav Nilsonne, Frank Konietschke, Sophie K. Piper, Samuel Pawel, Charlotte Micheloud, Leonhard Held, Florian Frommlet, Daniel Segelcke, Esther M. Pogatzki-Zahn, Bernhard Voelkl, Tim Friede, Edgar Brunner, Astrid Dempfle, Bernhard Haller, Marie Juliane Jung, Lars Björn Riecken, Hans-Georg Kuhn, Matthias Tenbusch, Lina Maria Serna Higuita, Edmond J. Remarque, Servan Luciano Grüninger-Egli, Katrin Manske, Sebastian Kobold, Marion Rivalan, Lisa Wedekind, Juliane C. Wilcke, Anne-Laure Boulesteix, Marcus W. Meinhardt, Rainer Spanagel, Simone Hettmer, Irene von Lüttichau, Carla Regina, Ulrich Dirnagl, Ulf Toelch
Publikováno v:
Translational Medicine Communications, Vol 7, Iss 1, Pp 1-13 (2022)
Abstract Clinical translation from bench to bedside often remains challenging even despite promising preclinical evidence. Among many drivers like biological complexity or poorly understood disease pathology, preclinical evidence often lacks desired
Externí odkaz:
https://doaj.org/article/bf47b97f5e2949fb928a3da8d60cd224
Autor:
Vugar Azizov, Michel Hübner, Michael Frech, Jörg Hofmann, Marketa Kubankova, Dennis Lapuente, Matthias Tenbusch, Jochen Guck, Georg Schett, Mario M. Zaiss
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107230- (2023)
Summary: Alcohol is among the most widely consumed dietary substances. Excessive alcohol consumption damages the liver, heart, and brain. Alcohol also has strong immunoregulatory properties. Here, we report how alcohol impairs T cell function via ace
Externí odkaz:
https://doaj.org/article/4f38ace1511c4f95970755bb2e6a147e
Autor:
Anna Schmidt, Basudev Paudyal, Sonia Villanueva-Hernández, Adam Mcnee, Eleni Vatzia, Brigid Veronica Carr, Selma Schmidt, Amy Mccarron, Veronica Martini, Silke Schroedel, Christian Thirion, Ryan Waters, Francisco J. Salguero, Wilhelm Gerner, Matthias Tenbusch, Elma Tchilian
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
T cell responses directed against highly conserved viral proteins contribute to the clearance of the influenza virus and confer broadly cross-reactive and protective immune responses against a range of influenza viruses in mice and ferrets. We examin
Externí odkaz:
https://doaj.org/article/7a124e0b2d554bd1b327bae9c7f98cfe
Autor:
Philip Podschwadt, Anna Malyshkina, Sonja Windmann, Athanasios Papadamakis, Leonie Kerkmann, Dennis Lapuente, Matthias Tenbusch, Mengji Lu, Michael Schindler, Karl Sebastian Lang, Wiebke Hansen, Wibke Bayer
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Retroviral envelope (Env) proteins have long been recognized to exhibit immunosuppressive properties, which affect the CD8+ T-cell response to an infection but also to immunization. Interestingly, we previously showed in the Friend murine leukemia vi
Externí odkaz:
https://doaj.org/article/f61df26f123f489f9237b43dcb2f1058
Autor:
Natalie Heinen, Corinna Sophie Marheinecke, Clara Bessen, Arturo Blazquez-Navarro, Toralf Roch, Ulrik Stervbo, Moritz Anft, Carlos Plaza-Sirvent, Sandra Busse, Mara Klöhn, Jil Schrader, Elena Vidal Blanco, Doris Urlaub, Carsten Watzl, Markus Hoffmann, Stefan Pöhlmann, Matthias Tenbusch, Eike Steinmann, Daniel Todt, Carsten Hagenbeck, Gert Zimmer, Wolfgang Ekkehard Schmidt, Daniel Robert Quast, Nina Babel, Ingo Schmitz, Stephanie Pfänder
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
With the emergence of novel Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) Variants of Concern (VOCs), vaccination studies that elucidate the efficiency and effectiveness of a vaccination campaign are critical to assess the durability a
Externí odkaz:
https://doaj.org/article/77dc03f4f7d54c428069378f6feeec11
Autor:
Dennis Lapuente, Jana Fuchs, Jonas Willar, Ana Vieira Antão, Valentina Eberlein, Nadja Uhlig, Leila Issmail, Anna Schmidt, Friederike Oltmanns, Antonia Sophia Peter, Sandra Mueller-Schmucker, Pascal Irrgang, Kirsten Fraedrich, Andrea Cara, Markus Hoffmann, Stefan Pöhlmann, Armin Ensser, Cordula Pertl, Torsten Willert, Christian Thirion, Thomas Grunwald, Klaus Überla, Matthias Tenbusch
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
While current COVID-19 vaccines provide certain protection, more effective vaccination strategies are still desirable. Here the authors show, using mouse vaccination models, that priming with a systemic mRNA and boosting with an intranasal adenoviral
Externí odkaz:
https://doaj.org/article/2d658f5bfe1141c4acf2fa4bf72300b6