Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Matthias, Sendler"'
Autor:
Fabian Frost, Valeria Khaimov, Volkmar Senz, Stefan Weiss, Bastian Klußmann-Fricke, Malte Rühlemann, Corinna Bang, Andre Franke, Tilman Pickartz, Christoph Budde, Ali A. Aghdassi, Stefan Siewert, Frank U. Weiss, Niels Grabow, Markus M. Lerch, Matthias Sendler
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
BackgroundDevelopment of pancreatic necroses or pseudocysts are typical complications of pancreatitis and may require endoscopic drainage therapy using metal or plastic stents. Microbial infection of these lesions poses a major challenge. So far, the
Externí odkaz:
https://doaj.org/article/a53b2c32f88842aca6196cc54f962ef6
Autor:
Franziska G. Thiel, Saeedeh Asgarbeik, Juliane Glaubitz, Anika Wilden, Markus M. Lerch, Frank Ulrich Weiss, Matthias Sendler
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Acute pancreatitis (AP), which is characterized by self-digestion of the pancreas by its own prematurely activated digestive proteases, is a major reason for hospitalization. The autodigestive process causes necrotic cell death of pancreatic
Externí odkaz:
https://doaj.org/article/a0b7bc8c0135489c964a26e3672dc64a
Autor:
Juliane Glaubitz, Saeedeh Asgarbeik, Rabea Lange, Hala Mazloum, Hager Elsheikh, Frank Ulrich Weiss, Matthias Sendler
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Acute pancreatitis (AP) is one of the most common inflammatory diseases of the gastrointestinal tract and a steady rising diagnosis for inpatient hospitalization. About one in four patients, who experience an episode of AP, will develop chronic pancr
Externí odkaz:
https://doaj.org/article/a92272404a7f4303b622b15892ebbe70
Autor:
Mats L. Wiese, Steffi Urban, Sabrina von Rheinbaben, Fabian Frost, Matthias Sendler, Frank Ulrich Weiss, Robin Bülow, Marie-Luise Kromrey, Quang Trung Tran, Markus M. Lerch, Birgit Schauer, Ali A. Aghdassi
Publikováno v:
BMC Gastroenterology, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background In acute pancreatitis, secondary infection of pancreatic necrosis is a complication that mostly necessitates interventional therapy. A reliable prediction of infected necrotizing pancreatitis would enable an early identification o
Externí odkaz:
https://doaj.org/article/6c2e1cfe10ee45cb929a4f826258f0d8
Autor:
Juliane Glaubitz, Anika Wilden, Janine Golchert, Georg Homuth, Uwe Völker, Barbara M. Bröker, Thomas Thiele, Markus M. Lerch, Julia Mayerle, Ali A. Aghdassi, Frank U. Weiss, Matthias Sendler
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
The function of T regulatory cells in the tissue fibrosis in chronic pancreatitis is not fully understood. Here the authors use a mouse model of chronic pancreatitis to show that Treg cells reduce IL-4 mediated chronic inflammation in the pancreas as
Externí odkaz:
https://doaj.org/article/332d0ba357ad49519705c0efff46dce0
Autor:
Anika Wilden, Juliane Glaubitz, Oliver Otto, Doreen Biedenweg, Matthias Nauck, Matthias Mack, Silvia Ribback, Barbara M. Bröker, Sabrina Freiin von Rheinbaben, Markus M. Lerch, Ali Alexander Aghdassi, Frank Ulrich Weiss, Matthias Sendler
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
ObjectiveAcute pancreatitis (AP) is an inflammatory disorder, the severe form of which is burdened with multi-organ dysfunction and high mortality. The pathogenesis of life –threatening organ complications, such as respiratory and renal failure, is
Externí odkaz:
https://doaj.org/article/d1e9aa03df9f4fc689f8cc3d1042bf04
Autor:
Fabian Frost, Tim Kacprowski, Malte Rühlemann, Stefan Weiss, Corinna Bang, Andre Franke, Maik Pietzner, Ali A. Aghdassi, Matthias Sendler, Uwe Völker, Henry Völzke, Julia Mayerle, Frank U. Weiss, Georg Homuth, Markus M. Lerch
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Gallstone disease affects up to twenty percent of the population in western countries and is a significant contributor to morbidity and health care expenditure. Intestinal microbiota have variously been implicated as either contributing to g
Externí odkaz:
https://doaj.org/article/475fbfa266654d25ba6d1a4c3a5fb3e3
Autor:
Quang Trung Tran, Matthias Sendler, Mats L. Wiese, Julia Doller, Lukas Zierke, Marcel Gischke, Juliane Glaubitz, Van Huy Tran, Michael Lalk, Uwe T. Bornscheuer, Frank Ulrich Weiss, Markus M. Lerch, Ali A. Aghdassi
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 13592 (2022)
Acute pancreatitis (AP) is a major, globally increasing gastrointestinal disease and a biliary origin is the most common cause. However, the effects of bile acids (BAs), given systemically, on the pancreas and on disease severity remains elusive. In
Externí odkaz:
https://doaj.org/article/a4b7e7b0a3d346f0bac0852243595405
Autor:
Agnieszka Smolinska, Kerstin Singer, Janine Golchert, Urszula Smyczynska, Wojciech Fendler, Matthias Sendler, Jens van den Brandt, Stephan Singer, Georg Homuth, Markus M. Lerch, Patryk Moskwa
Publikováno v:
Cancers, Vol 14, Iss 17, p 4077 (2022)
Pancreatic ductal adenocarcinoma (PDAC), due to its genomic heterogeneity and lack of effective treatment, despite decades of intensive research, will become the second leading cause of cancer-related deaths by 2030. Step-wise acquisition of mutation
Externí odkaz:
https://doaj.org/article/0a512cb0015b4add901aff660d6c55eb
Autor:
Agnieszka Smolinska, Julia Swoboda, Wojciech Fendler, Markus M. Lerch, Matthias Sendler, Patryk Moskwa
Publikováno v:
Heliyon, Vol 6, Iss 1, Pp e03187- (2020)
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers. Acquired inherited and/or somatic mutations drive its development. In order to prevent the formation of these mutations, precise and immediate repair of any DNA damage is indisp
Externí odkaz:
https://doaj.org/article/6aaefa8eb86248798f93f6bc90459982