Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Matthias, Sausbier"'
Autor:
Olga Schweigert, Julia Adler, Melanie Cruz Santos, Robert Lukowski, Tanja Zeller, Felicia Kleusberg, Amelie Knauer, Peter Ruth, Matthias Sausbier, Natalie Längst
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 18
International Journal of Molecular Sciences, Vol 22, Iss 9925, p 9925 (2021)
Volume 22
Issue 18
International Journal of Molecular Sciences, Vol 22, Iss 9925, p 9925 (2021)
The cysteine-rich LIM-only protein 4 (CRP4), a LIM-domain and zinc finger containing adapter protein, has been implicated as a downstream effector of the second messenger 3′,5′-cyclic guanosine monophosphate (cGMP) pathway in multiple cell types,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b78d3b0a914ca7abba1279f52d2158e3
Autor:
Martin Oeggerli, Yuemin Tian, Christian Ruiz, Barbara Wijker, Guido Sauter, Ellen Obermann, Uwe Güth, Inti Zlobec, Matthias Sausbier, Karl Kunzelmann, Lukas Bubendorf
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e41664 (2012)
KCNMA1 encodes the α-subunit of the large conductance, voltage and Ca(2+)-activated (BK) potassium channel and has been reported as a target gene of genomic amplification at 10q22 in prostate cancer. To investigate the prevalence of the amplificatio
Externí odkaz:
https://doaj.org/article/0ec1d421774e4a2db7de18cbffa9c12a
Autor:
Ulrike Sausbier, Christian Dullin, Jeannine Missbach-Guentner, Clement Kabagema, Katarina Flockerzie, Gerd Marten Kuscher, Walter Stuehmer, Winfried Neuhuber, Peter Ruth, Frauke Alves, Matthias Sausbier
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21168 (2011)
BACKGROUND: The process of bone resorption by osteoclasts is regulated by Cathepsin K, the lysosomal collagenase responsible for the degradation of the organic bone matrix during bone remodeling. Recently, Cathepsin K was regarded as a potential targ
Externí odkaz:
https://doaj.org/article/89e23862e5c54a95be70dba0d4c259ee
Autor:
Yiliu Liao, Ase-Marit Kristiansen, Cecilie P Oksvold, Frode A Tuvnes, Ning Gu, Elise Rundén-Pran, Peter Ruth, Matthias Sausbier, Johan F Storm
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15601 (2010)
Neuronal calcium-activated potassium channels of the BK type are activated by membrane depolarization and intracellular Ca(2+) ions. It has been suggested that these channels may play a key neuroprotective role during and after brain ischemia, but th
Externí odkaz:
https://doaj.org/article/b73ee1a14d17429b8dcddd27a8744b41
Autor:
Guy Cheron, Matthias Sausbier, Ulrike Sausbier, Winfried Neuhuber, Peter Ruth, Bernard Dan, Laurent Servais
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7991 (2009)
Calcium signaling plays a central role in normal CNS functioning and dysfunction. As cerebellar Purkinje cells express the major regulatory elements of calcium control and represent the sole integrative output of the cerebellar cortex, changes in neu
Externí odkaz:
https://doaj.org/article/bea1eee4164d4d298b3ab25f80af1b7b
Autor:
Christoph K. Moeller, Marlies Knipper, Ulrike Zimmermann, Winfried Neuhuber, Lukas Rüttiger, Matthias Sausbier, Harald van Straaten, Niels Brandt, Holger Schulze, Simone Kurt, Jennifer Kindler, Jutta Engel, Ulrike Sausbier, Peter Ruth
Publikováno v:
The FASEB Journal
Large conductance, voltage- and Ca2+-activated K+ (BK) channels in inner hair cells (IHCs) of the cochlea are essential for hearing. However, germline deletion of BKα, the pore-forming subunit KCNMA1 of the BK channel, surprisingly did not affect he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8e1646a06e4ad65e574081bc6e935d1
https://doi.org/10.1096/fj.11-200535
https://doi.org/10.1096/fj.11-200535
Autor:
Arthur Konnerth, Horst A. Henning, Yosef Yarom, Helmuth Adelsberger, Peter Ruth, Matthias Sausbier, Georg Wietzorrek, Xiaowei Chen, Yury Kovalchuk
Publikováno v:
Proceedings of the National Academy of Sciences. 107:12323-12328
The large-conductance voltage- and calcium-activated potassium (BK) channels are ubiquitously expressed in the brain and play an important role in the regulation of neuronal excitation. Previous work has shown that the total deletion of these channel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9775c68bc50c6efe7da39eb793784d24
https://doi.org/10.1073/pnas.1001745107
https://doi.org/10.1073/pnas.1001745107
Autor:
Mads V. Sorensen, Matthias Sausbier, Helle A. Praetorius, Brigitte Riederer, Ursula Seidler, Jens Leipziger, Peter Ruth
Publikováno v:
The Journal of Physiology. 588:1763-1777
Colonic epithelial K+ secretion is a two-step transport process with initial K+ uptake over the basolateral membrane followed by K+ channel-dependent exit into the lumen. In this process the large-conductance, Ca2+-activated KCa1.1 (BK) channel has b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::753b60b41291f64bb880daba2f15e417
https://doi.org/10.1113/jphysiol.2009.181933
https://doi.org/10.1113/jphysiol.2009.181933
Autor:
Emine Utku, Peter Ruth, Michael Korth, Ulrike Sausbier, Xiaobo Zhou, Iris Wulfsen, Thomas Wieland, Matthias Sausbier
Publikováno v:
Proceedings of the National Academy of Sciences. 107:8005-8010
Large conductance voltage- and Ca 2+ -activated potassium channels (BK channels) are important feedback regulators in excitable cells and are potently regulated by protein kinases. The present study reveals a dual role of protein kinase C (PKC) on BK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a66c71ebc483614dfbbab0add61da4e1
https://doi.org/10.1073/pnas.0912029107
https://doi.org/10.1073/pnas.0912029107
Autor:
Tobias Lamkemeyer, Andreas Jakob, Winfried Neuhuber, Angela Wirth, Johannes Madlung, Patrick Pankert, Alfred Nordheim, Franz Sprossmann, Michael J. Shipston, Ulrike Sausbier, Stefan Offermanns, Iancu Bucurenciu, Xiaobo Zhou, Michael Korth, Matthias Sausbier, Peter Ruth, Hong Zhao
Publikováno v:
FEBS Journal. 276:1680-1697
The large-conductance, voltage-dependent and Ca(2+)-dependent K(+) (BK) channel links membrane depolarization and local increases in cytosolic free Ca(2+) to hyperpolarizing K(+) outward currents, thereby controlling smooth muscle contractility. Cons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8924b47fc7d373c5db0b65f27844d145
https://doi.org/10.1111/j.1742-4658.2009.06900.x
https://doi.org/10.1111/j.1742-4658.2009.06900.x