Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Matthias, Glaser"'
Autor:
Timothy H. Witney, Erik Årstad, Sanjiv S. Gambhir, Mark F. Lythgoe, Norman Koglin, Mathias Berndt, David Y. Lewis, Adam J. Shuhendler, Tong Zhang, Aileen Hoehne, Gayatri Gowrishankar, Kerstin Sander, Thibault Gendron, Oliver D.K. Maddocks, Matthias Glaser, Hannah E. Greenwood, Patrick N. McCormick
The cell's endogenous antioxidant system is vital to maintain redox homeostasis. Despite its central role in normal and pathophysiology, no noninvasive tools exist to measure this system in patients. The cystine/glutamate antiporter system xc− main
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2065d87b8278bbaa19696a76564467ad
https://doi.org/10.1158/0008-5472.c.6511257.v2
https://doi.org/10.1158/0008-5472.c.6511257.v2
Autor:
Timothy H. Witney, Erik Årstad, Sanjiv S. Gambhir, Mark F. Lythgoe, Norman Koglin, Mathias Berndt, David Y. Lewis, Adam J. Shuhendler, Tong Zhang, Aileen Hoehne, Gayatri Gowrishankar, Kerstin Sander, Thibault Gendron, Oliver D.K. Maddocks, Matthias Glaser, Hannah E. Greenwood, Patrick N. McCormick
Supplementary Methods and Figures 1 - 6. Fig. S1 shows effect of TBHP treatment on ROS and [18F]FSPG uptake in ovarian cancer cell lines; Fig. S2 illustrates the relationship between glutamate and cystine concentrations on [18F]FSPG uptake; Fig. S3 q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0f236636b3f2dc4d1461825c6519115
https://doi.org/10.1158/0008-5472.22658688
https://doi.org/10.1158/0008-5472.22658688
Autor:
Timothy H. Witney, Daniel Hochhauser, Erik Årstad, Mark F. Lythgoe, Norman Koglin, Tong Zhang, Kerstin Sander, Oliver D. K. Maddocks, Raul Pereira, Matthias Glaser, Thibault Gendron, Patrick N. McCormick, Hannah E. Greenwood
Video 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::235bf2863a0ff7e781e29db5353bb8b9
https://doi.org/10.1158/1078-0432.22474152.v1
https://doi.org/10.1158/1078-0432.22474152.v1
Autor:
Timothy H. Witney, Erik Årstad, Sanjiv S. Gambhir, Mark F. Lythgoe, Norman Koglin, Mathias Berndt, David Y. Lewis, Adam J. Shuhendler, Tong Zhang, Aileen Hoehne, Gayatri Gowrishankar, Kerstin Sander, Thibault Gendron, Oliver D.K. Maddocks, Matthias Glaser, Hannah E. Greenwood, Patrick N. McCormick
Movie S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53f8881fcd58481fb47f7c8c09764dbc
https://doi.org/10.1158/0008-5472.22422543.v1
https://doi.org/10.1158/0008-5472.22422543.v1
Autor:
Timothy H. Witney, Daniel Hochhauser, Erik Årstad, Mark F. Lythgoe, Norman Koglin, Tong Zhang, Kerstin Sander, Oliver D. K. Maddocks, Raul Pereira, Matthias Glaser, Thibault Gendron, Patrick N. McCormick, Hannah E. Greenwood
Purpose:Drug resistance is a major obstacle for the effective treatment of patients with high-grade serous ovarian cancer (HGSOC). Currently, there is no satisfactory way to identify patients with HGSOC that are refractive to the standard of care. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b55c4da8babde672fc84da00ebc7012
https://doi.org/10.1158/1078-0432.c.6528699.v1
https://doi.org/10.1158/1078-0432.c.6528699.v1
Autor:
Timothy H. Witney, Daniel Hochhauser, Erik Årstad, Mark F. Lythgoe, Norman Koglin, Tong Zhang, Kerstin Sander, Oliver D. K. Maddocks, Raul Pereira, Matthias Glaser, Thibault Gendron, Patrick N. McCormick, Hannah E. Greenwood
Supplementary Figures 1 - 6. Fig. S1 shows the ability of PEO1, PEO4 and PEO6 cells to form colonies following cisplatin treatment; Fig. S2 demonstrates that [18F]FDG uptake in A2780 cells is unrelated to drug resistance; Fig. S3 examines the express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5176fc1bd6731a7f7c9924030168f5ec
https://doi.org/10.1158/1078-0432.22474134.v1
https://doi.org/10.1158/1078-0432.22474134.v1
Autor:
Helen Allan, Matthias Glaser, Erik Årstad, Robin Bofinger, Gregory Weitsman, Daniel Hochhauser, Tammy L. Kalber, Kerstin Sander, Tony Ng, Rachel Evans, Helen C. Hailes, Alethea B. Tabor
Publikováno v:
Nanoscale. 13:18520-18535
In vivo delivery of small molecule therapeutics to cancer cells, assessment of the selectivity of administration, and measuring the efficacity of the drug in question at the molecule level, are important ongoing challenges in developing new classes o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21cf0bfc56ddd371f77f143db3789a24
https://doi.org/10.1039/d1nr02770k
https://doi.org/10.1039/d1nr02770k
Autor:
Robin, Bofinger, Gregory, Weitsman, Rachel, Evans, Matthias, Glaser, Kerstin, Sander, Helen, Allan, Daniel, Hochhauser, Tammy L, Kalber, Erik, Årstad, Helen C, Hailes, Tony, Ng, Alethea B, Tabor
Publikováno v:
Nanoscale
In vivo delivery of small molecule therapeutics to cancer cells, assessment of the selectivity of administration, and measuring the efficacity of the drug in question at the molecule level, are important ongoing challenges in developing new classes o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a699473470faaa56cc6a69b3afb54628
https://pubmed.ncbi.nlm.nih.gov/34730152
https://pubmed.ncbi.nlm.nih.gov/34730152
Autor:
Julian Grigg, Duncan Hiscock, Bard Indrevoll, Lone Omtvedt, Matthias Glaser, Dimitrios Mantzilas, Sajinder K. Luthra, Shales Jonathan Robert, Peter Iveson
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 62:925-932
An 18 F-labelled human epidermal growth factor receptor (HER2) receptor binding radiotracer is a potential tool to non-invasively identify HER2 positive tumour lesions in subjects with recurrent metastatic breast cancer. Having explored the manual ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92d79f024a8ebb7ea553dd2e7a3ed620
https://doi.org/10.1002/jlcr.3789
https://doi.org/10.1002/jlcr.3789
Autor:
Fatih Sirindil, Erik Arstad, Kerstin Sander, Ramla Awais, Frazer Twyman, Camila Marcolan, Matthias Glaser
Publikováno v:
Nuclear Medicine and Biology. :S137
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::884184c7c951a7dea089588832da663e
https://doi.org/10.1016/s0969-8051(22)00298-0
https://doi.org/10.1016/s0969-8051(22)00298-0