Zobrazeno 1 - 10
of 163
pro vyhledávání: '"Matthias, Edinger"'
Autor:
Chunguang Liang, Silvia Spoerl, Yin Xiao, Katharina M. Habenicht, Sigrun S. Haeusl, Isabel Sandner, Julia Winkler, Nicholas Strieder, Rüdiger Eder, Hanna Stanewsky, Christoph Alexiou, Diana Dudziak, Andreas Rosenwald, Matthias Edinger, Michael Rehli, Petra Hoffmann, Thomas H. Winkler, Friederike Berberich-Siebelt
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract In clinical situations, peripheral blood accessible CD3+CD4+CXCR5+ T-follicular helper (TFH) cells may have to serve as a surrogate indicator for dysregulated germinal center responses in tissues. To determine the heterogeneity of TFH cells
Externí odkaz:
https://doaj.org/article/7c0d3bc23f4c4d5f842af48b76085e66
Autor:
Ana F. David, Andreas Heinzel, Michael Kammer, Constantin Aschauer, Roman Reindl-Schwaighofer, Karin Hu, Hao-Shan Chen, Moritz Muckenhuber, Anna Kubetz, Anna Marianne Weijler, Nina Worel, Matthias Edinger, Gabriela Berlakovich, Thomas Lion, Megan Sykes, Thomas Wekerle, Rainer Oberbauer
Publikováno v:
EBioMedicine, Vol 106, Iss , Pp 105239- (2024)
Summary: Background: Induction of donor-specific tolerance is a promising approach to achieve long-term graft patency in transplantation with little to no maintenance immunosuppression. Changes to the recipient’s T cell receptor (TCR) repertoire ar
Externí odkaz:
https://doaj.org/article/69c8c427a95a467183299b934f4767c4
Autor:
David J. Dittmar, Franziska Pielmeier, Nicholas Strieder, Alexander Fischer, Michael Herbst, Hanna Stanewsky, Niklas Wenzl, Eveline Röseler, Rüdiger Eder, Claudia Gebhard, Lucia Schwarzfischer-Pfeilschifter, Christin Albrecht, Wolfgang Herr, Matthias Edinger, Petra Hoffmann, Michael Rehli
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract The adoptive transfer of regulatory T cells is a promising strategy to prevent graft-versus-host disease after allogeneic bone marrow transplantation. Here, we use a major histocompatibility complex-mismatched mouse model to follow the fate
Externí odkaz:
https://doaj.org/article/cd59538751e841828e7e13a2de010b68
Autor:
Markus Perl, Konstantin Herfeld, Dennis C. Harrer, Matthias Höpting, Marina Schweiger, Ulrich Sterz, Leonard Knödler, Susanne Heimerl, Leo Hansmann, Wolfgang Herr, Hendrik Poeck, Daniel Wolff, Matthias Edinger, Christina Hart, Matthias A. Fante
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Chimeric antigen receptor (CAR-) T cell therapy causes serious side effects including cytokine release syndrome (CRS). CRS-related coagulopathy is associated with hypofibrinogenemia that is thus far considered the result of disseminated intravascular
Externí odkaz:
https://doaj.org/article/e29209f4a56541ba8d1fab59aae25ed7
Autor:
Ronja Langer, Antonela Lelas, Michael Rittenschober, Agnieszka Piekarska, Alicja Sadowska-Klasa, Ivan Sabol, Lana Desnica, Hildegard Greinix, Anne Dickinson, Marit Inngjerdingen, Anita Lawitschka, Radovan Vrhovac, Drazen Pulanic, Sibel Güneş, Stefan Klein, Jan Moritz Middeke, Matthias Grube, Matthias Edinger, Wolfgang Herr, Daniel Wolff
Publikováno v:
Frontiers in Transplantation, Vol 3 (2024)
IntroductionChronic graft-versus-host disease (cGvHD) is a serious late complication of allogeneic hematopoietic stem cell transplantation (allo-HSCT).MethodsThis multicenter analysis determined the cumulative incidence (CI) of cGvHD and late acute G
Externí odkaz:
https://doaj.org/article/b9a9e77daa68498cbbc630af6a7295bf
Publikováno v:
Radiation Oncology, Vol 17, Iss 1, Pp 1-12 (2022)
Abstract Background Total body irradiation (TBI)-based-conditioning before allogeneic hematopoietic stem cell transplantation (allo-HSCT) is standard of care in patients with acute myeloid leukemia (AML) but can cause long-term morbidity. Data on the
Externí odkaz:
https://doaj.org/article/09d3b435c4fa42ee91a2b5f37538b1ec
Autor:
Dennis Christoph Harrer, Alexander Denk, Felix Keil, Karin Menhart, Stephanie Mayer, Daniel Wolff, Matthias Edinger, Wolfgang Herr, Matthias Grube
Publikováno v:
eJHaem, Vol 3, Iss 3, Pp 1003-1008 (2022)
Abstract Burkitt leukemia (BL) represents a highly aggressive lymphoma characterized by proliferation rates of around 100%, and a frequent spread into the central nervous system. If standard frontline chemotherapy fails, the prognosis is usually dism
Externí odkaz:
https://doaj.org/article/bc5c87a80bee44aabdb75d70578d3977
Autor:
Lucia Scheidler, Katrin Hippe, Sakhila Ghimire, Daniela Weber, Markus Weber, Elisabeth Meedt, Petra Hoffmann, Petra Lehn, Ralph Burkhardt, Andreas Mamilos, Matthias Edinger, Daniel Wolff, Hendrik Poeck, Matthias Evert, Andre Gessner, Wolfgang Herr, Ernst Holler
Publikováno v:
Haematologica, Vol 108, Iss 11 (2023)
Intestinal immunoglobulin A (IgA) is strongly involved in microbiota homeostasis. Since microbiota disruption is a major risk factor of acute graft-versus-host disease (GvHD), we addressed the kinetics of intestinal IgA-positive (IgA+) plasma cells b
Externí odkaz:
https://doaj.org/article/8f1272643dd64c11be40b69110048012
Autor:
Martina Seefried, Nadine Hundhausen, Irena Kroeger, Maike Büttner-Herold, Petra Hoffmann, Matthias Edinger, Evelyn Ullrich, Friederike Berberich-Siebelt, William J. Britt, Michael Mach, Thomas H. Winkler
Publikováno v:
JCI Insight, Vol 8, Iss 5 (2023)
Reactivation of human cytomegalovirus (HCMV) from latency is a frequent complication following hematopoietic stem cell transplantation (HSCT). The development of acute graft-versus-host disease (GVHD) is a significant risk factor for HCMV disease. Us
Externí odkaz:
https://doaj.org/article/85e5e8164bca4a6aa5ac4dbeda5eced2
Autor:
Alexandros Spyridonidis, Myriam Labopin, Bipin Savani, Sebastian Giebel, Gesine Bug, Stefan Schönland, Nicolaus Kröger, Matthias Stelljes, Thomas Schroeder, Andrew McDonald, Igor-Wolfgang Blau, Martin Bornhäuser, Montse Rovira, Wolfgang Bethge, Andreas Neubauer, Arnold Ganser, Jean Henri Bourhis, Matthias Edinger, Bruno Lioure, Gerald Wulf, Kerstin Schäfer-Eckart, Mutlu Arat, Zinaida Peric, Christoph Schmid, Ali Bazarbachi, Fabio Ciceri, Arnon Nagler, Mohamad Mohty
Publikováno v:
HemaSphere, Vol 7, Iss 1, p e812 (2023)
In this registry-based study, we compared outcomes of allogeneic hematopoietic cell transplantation (allo-HCT) in adult patients with acute lymphoblastic leukemia (ALL) transplanted in first complete remission (CR-1), following conditioning with tota
Externí odkaz:
https://doaj.org/article/eb30afc7089b40299a7ace1e15bb6dbe