Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Matthias, Budt"'
Autor:
Nico Joel Halwe, Lea Hamberger, Julia Sehl-Ewert, Christin Mache, Jacob Schön, Lorenz Ulrich, Sten Calvelage, Mario Tönnies, Jonas Fuchs, Pooja Bandawane, Madhumathi Loganathan, Anass Abbad, Juan Manuel Carreño, Maria C. Bermúdez-González, Viviana Simon, Ahmed Kandeil, Rabeh El-Shesheny, Mohamed A. Ali, Ghazi Kayali, Matthias Budt, Stefan Hippenstiel, Andreas C. Hocke, Florian Krammer, Thorsten Wolff, Martin Schwemmle, Kevin Ciminski, Donata Hoffmann, Martin Beer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-8 (2024)
Abstract Influenza A viruses (IAVs) of subtype H9N2 have reached an endemic stage in poultry farms in the Middle East and Asia. As a result, human infections with avian H9N2 viruses have been increasingly reported. In 2017, an H9N2 virus was isolated
Externí odkaz:
https://doaj.org/article/27c9b3ce2fd746359b0b64d22dcabd10
Autor:
Tim Krischuns, Benoît Arragain, Catherine Isel, Sylvain Paisant, Matthias Budt, Thorsten Wolff, Stephen Cusack, Nadia Naffakh
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract The current model is that the influenza virus polymerase (FluPol) binds either to host RNA polymerase II (RNAP II) or to the acidic nuclear phosphoprotein 32 (ANP32), which drives its conformation and activity towards transcription or replic
Externí odkaz:
https://doaj.org/article/b3842536fde24ca59325f1c6a87e2e03
Autor:
Livia V. Patrono, Bram Vrancken, Matthias Budt, Ariane Düx, Sebastian Lequime, Sengül Boral, M. Thomas P. Gilbert, Jan F. Gogarten, Luisa Hoffmann, David Horst, Kevin Merkel, David Morens, Baptiste Prepoint, Jasmin Schlotterbeck, Verena J. Schuenemann, Marc A. Suchard, Jeffery K. Taubenberger, Luisa Tenkhoff, Christian Urban, Navena Widulin, Eduard Winter, Michael Worobey, Thomas Schnalke, Thorsten Wolff, Philippe Lemey, Sébastien Calvignac-Spencer
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
For archival pathogens, like pH1N1 Influenza A virus the causative agent of 1918/19 pandemic, only few whole genome sequences exist. Here, Patrono et al. provide one complete and two partial genomes from Germany and find variation in two sites in the
Externí odkaz:
https://doaj.org/article/9dc808b2361749148435b2f276f513a4
Autor:
Boris Bogdanow, Xi Wang, Katrin Eichelbaum, Anne Sadewasser, Immanuel Husic, Katharina Paki, Matthias Budt, Martha Hergeselle, Barbara Vetter, Jingyi Hou, Wei Chen, Lüder Wiebusch, Irmtraud M. Meyer, Thorsten Wolff, Matthias Selbach
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Avian influenza A virus (IAV) strains replicate poorly in mammalian hosts, but mechanisms underlying species restriction are incompletely understood. Here, Bogdanow et al. show that avian and mammalian adapted IAV strains have evolved different RNA s
Externí odkaz:
https://doaj.org/article/31c5226fb8bf4e6b9bc945e1829498fd
Autor:
Nico Halwe, Lea Hamberger, Julia Sehl-Ewert, Christin Mache, Jacob Schön, Lorenz Ulrich, Sten Calvelage, Jonas Fuchs, Pooja Bandawane, Madhumathi Loganathan, Anass Abbad, Juan Manuel Carreño, Viviana Simon, Ghazi Kayali, Mario Tönnies, Ahmed Kandeil, Rabeh El-Shesheny, Mohamed Ali, Thorsten Wolff, Matthias Budt, Stefan Hippenstiel, Andreas Hocke, Florian Krammer, Martin Schwemmle, Kevin Ciminski, Donata Hoffmann, Maria Bermudez-Gonzalez, Martin Beer
An Old-World bat H9N2 influenza A virus (IAV) identified in Egypt exhibits high replication and transmission potential in ferrets, efficient infection of human lung explant cultures and marked escape from the antiviral activity of MxA. Together with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09c7ef7139d99638f46f3219c8b22928
https://doi.org/10.21203/rs.3.rs-2937503/v1
https://doi.org/10.21203/rs.3.rs-2937503/v1
Autor:
Sébastien Calvignac-Spencer, Matthias Budt, Matthew Huska, Hugues Richard, Luca Leipold, Linus Grabenhenrich, Torsten Semmler, Max von Kleist, Stefan Kröger, Thorsten Wolff, Martin Hölzer
Publikováno v:
Viruses, Vol 13, Iss 8, p 1491 (2021)
Here, we report on the increasing frequency of the SARS-CoV-2 lineage A.27 in Germany during the first months of 2021. Genomic surveillance identified 710 A.27 genomes in Germany as of 2 May 2021, with a vast majority identified in laboratories from
Externí odkaz:
https://doaj.org/article/c35a254cbc19471abd2f84a3fc6b0054
Autor:
Djin Ye, Oh, Martin, Hölzer, Sofia, Paraskevopoulou, Maria, Trofimova, Felix, Hartkopf, Matthias, Budt, Marianne, Wedde, Hugues, Richard, Berit, Haldemann, Teresa, Domaszewska, Janine, Reiche, Kathrin, Keeren, Aleksandar, Radonić, Julia Patricia, Ramos Calderón, Maureen Rebecca, Smith, Annika, Brinkmann, Kathrin, Trappe, Oliver, Drechsel, Kathleen, Klaper, Sascha, Hein, Eberhardt, Hildt, Walter, Haas, Sébastien, Calvignac-Spencer, Torsten, Semmler, Ralf, Dürrwald, Andrea, Thürmer, Christian, Drosten, Stephan, Fuchs, Stefan, Kröger, Max, von Kleist, Thorsten, Wolff, Carsten, Tiemann
Publikováno v:
Clinical Infectious Diseases. 75:S110-S120
Background Comprehensive pathogen genomic surveillance represents a powerful tool to complement and advance precision vaccinology. The emergence of the Alpha variant in December 2020 and the resulting efforts to track the spread of this and other sev
Autor:
Djin-Ye Oh, Martin Hölzer, Sofia Paraskevopoulou, Maria Trofimova, Felix Hartkopf, Matthias Budt, Marianne Wedde, Hugues Richard, Berit Haldemann, Teresa Domaszewska, Janine Reiche, Kathrin Keeren, Aleksandar Radonić, Julia Patricia Ramos Calderón, Maureen Rebecca Smith, Annika Brinkmann, Kathrin Trappe, Oliver Drechsel, Kathleen Klaper, Sascha Hein, Eberhard Hildt, Walter Haas, Sébastien Calvignac-Spencer, Torsten Semmler, Ralf Dürrwald, Andrea Thürmer, Christian Drosten, Stephan Fuchs, Max von Kleist, Stefan Kröger, Thorsten Wolff
Publikováno v:
Open Forum Infectious Diseases. 9
Background The COVID-19 pandemic has demonstrated the importance of pathogen genomic surveillance. At RKI, the German National Institute of Public Health, we established the Integrated Molecular Surveillance for SARS-CoV-2 (IMS-SC2) network to perfor
Autor:
Livia V. Patrono, Bram Vrancken, Matthias Budt, Ariane Düx, Sebastian Lequime, Sengül Boral, M. Thomas P. Gilbert, Jan F. Gogarten, Luisa Hoffmann, David Horst, Kevin Merkel, David Morens, Baptiste Prepoint, Jasmin Schlotterbeck, Verena J. Schuenemann, Marc A. Suchard, Jeffery K. Taubenberger, Luisa Tenkhoff, Christian Urban, Navena Widulin, Eduard Winter, Michael Worobey, Thomas Schnalke, Thorsten Wolff, Philippe Lemey, Sébastien Calvignac-Spencer
Publikováno v:
Patrono, L V, Vrancken, B, Budt, M, Düx, A, Lequime, S, Boral, S, Gilbert, M T P, Gogarten, J F, Hoffmann, L, Horst, D, Merkel, K, Morens, D, Prepoint, B, Schlotterbeck, J, Schuenemann, V J, Suchard, M A, Taubenberger, J K, Tenkhoff, L, Urban, C, Widulin, N, Winter, E, Worobey, M, Schnalke, T, Wolff, T, Lemey, P & Calvignac-Spencer, S 2022, ' Archival influenza virus genomes from Europe reveal genomic variability during the 1918 pandemic ', Nature Communications, vol. 13, 2314 . https://doi.org/10.1038/s41467-022-29614-9
Nature Communications
Nature communications, vol 13, iss 1
Nature Communications, 13(1). Nature Publishing Group
Nature Communications
Nature communications, vol 13, iss 1
Nature Communications, 13(1). Nature Publishing Group
The 1918 influenza pandemic was the deadliest respiratory pandemic of the 20th century and determined the genomic make-up of subsequent human influenza A viruses (IAV). Here, we analyze both the first 1918 IAV genomes from Europe and the first from s
Autor:
Rocío Daviña Núñez, Matthias Budt, Sandra Saenger, Katharina Paki, Ulrike Arnold, Anne Sadewasser, Thorsten Wolff
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 7, p 1877 (2018)
Virus infections induce sensitive antiviral responses within the host cell. The RNA helicase retinoic acid-inducible gene I (RIG-I) is a key sensor of influenza virus RNA that induces the expression of antiviral type I interferons. Recent evidence su
Externí odkaz:
https://doaj.org/article/55f840af451f469baea794c97130fc76