Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Matthias, Bochtler"'
Autor:
Igor Helbrecht, Daniel Heiter, Weiwei Yang, Tamas Vincze, Andrew Hanneman, Thomas Lutz, Laurence Ettwiller, Matthias Bochtler, Shuang-yong Xu
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Winged helix (wH) domains, also termed winged helix-turn-helix (wHTH) domains, are widespread in all kingdoms of life and have diverse roles. In the context of DNA binding and DNA modification sensing, some eukaryotic wH domains are known as sensors
Externí odkaz:
https://doaj.org/article/c1bfdaf07b4c428e872de0fa5e3e2734
Autor:
Katarzyna Szczęśniak, Florian Veillard, Carsten Scavenius, Kamila Chudzik, Kinga Ferenc, Matthias Bochtler, Jan Potempa, Danuta Mizgalska
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT In Gram-negative didermal species of the phylum Bacteroidetes, the majority of pre(pro)proteins exported across the cell membrane via the Sec system follow the Q-rule: a glutamine residue immediately downstream of a leader peptide is exposed
Externí odkaz:
https://doaj.org/article/60967250674546a2b543e3272ba9043c
Autor:
Maria Winiewska-Szajewska, Honorata Czapinska, Magdalena Kaus-Drobek, Anna Fricke, Kinga Mieczkowska, Michał Dadlez, Matthias Bochtler, Jarosław Poznański
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract CK2 is a member of the CMGC group of eukaryotic protein kinases and a cancer drug target. It can be efficiently inhibited by halogenated benzotriazoles and benzimidazoles. Depending on the scaffold, substitution pattern, and pH, these compou
Externí odkaz:
https://doaj.org/article/89313d26965c4bf7973f9706ac44fdf1
Autor:
Katarzyna Niescierowicz, Leszek Pryszcz, Cristina Navarrete, Eugeniusz Tralle, Agata Sulej, Karim Abu Nahia, Marta Elżbieta Kasprzyk, Katarzyna Misztal, Abhishek Pateria, Adrianna Pakuła, Matthias Bochtler, Cecilia Winata
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Additional roles for A-to-I editing of RNA continue to be uncovered. Niescierowicz et al. report prevalent A-to-I editing in the zebrafish transcriptome, and the distinct maternal and zygotic functions of the editing enzyme Adar in embryonic patterni
Externí odkaz:
https://doaj.org/article/5ebee68a9d1049d8aa8186465707f125
Autor:
Thomas Lutz, Honorata Czapinska, Alexey Fomenkov, Vladimir Potapov, Daniel F. Heiter, Bo Cao, Peter Dedon, Matthias Bochtler, Shuang-yong Xu
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Modification dependent restriction endonucleases (MDREs) restrict modified DNA, typically with limited sequence specificity (∼2–4 bp). Here, we focus on MDREs that have an SRA and/or SBD (sulfur binding domain) fused to an HNH endonuclease domain
Externí odkaz:
https://doaj.org/article/4b58b90d7c874a5e895ee148c19d4cf9
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Thymine DNA glycosylase (TDG) and Nei-like 1 (NEIL1) have both been implicated in the base excision repair step of active DNA demethylation. The robust glycosylase activity of TDG on DNA substrates containing 5-formylcytosine (5fC) or 5-carb
Externí odkaz:
https://doaj.org/article/a06e6c568cea447086c90bc9e2eacf6e
Autor:
Andrea Fantuzzi, Patrycja Haniewicz, Domenica Farci, M Cecilia Loi, Keunha Park, Claudia Büchel, Matthias Bochtler, A William Rutherford, Dario Piano
Publikováno v:
Plant Physiology.
In thylakoid membranes, photosystem II (PSII) monomers from the stromal lamellae contain the subunits PsbS and Psb27 (PSIIm-S/27), while PSII monomers (PSIIm) from granal regions lack these subunits. Here, we have isolated and characterized these 2 t
Autor:
Anna Maria Stroynowska-Czerwinska, Magdalena Klimczak, Michal Pastor, Asgar Abbas Kazrani, Katarzyna Misztal, Matthias Bochtler
Publikováno v:
Cellular and Molecular Life Sciences. 80
Histone lysine-specific methyltransferase 2 (KMT2A-D) proteins, alternatively called mixed lineage leukemia (MLL1-4) proteins, mediate positive transcriptional memory. Acting as the catalytic subunits of human COMPASS-like complexes, KMT2A-D methylat
Autor:
Matthias Bochtler, Danuta Mizgalska, Florian Veillard, Magdalena L. Nowak, John Houston, Paul Veith, Eric C. Reynolds, Jan Potempa
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Bacteroidetes feature prominently in the human microbiome, as major colonizers of the gut and clinically relevant pathogens elsewhere. Here, we reveal a new Bacteroidetes specific feature in the otherwise widely conserved Sec/SPI (Sec translocase/sig
Externí odkaz:
https://doaj.org/article/3055a5309394476dbe8f1367af6bdfca
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179173 (2017)
TAL (transcription activator-like) effectors (TALEs) are bacterial proteins that are secreted from bacteria to plant cells to act as transcriptional activators. TALEs and related proteins (RipTALs, BurrH, MOrTL1 and MOrTL2) contain approximate tandem
Externí odkaz:
https://doaj.org/article/5c9d54a3dba442fea38bb49c4a33f6e1