Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Matthews O. Bradley"'
Autor:
Michael G. Silverman, Allyson G. Hindle, Jonathan S. Stamler, Matthews O. Bradley, Aurora Magliocca, Yusuke Miyazaki, Xiaowen Liu, Kei Hayashida, Shuichi Hirai, Michael W. Donnino, Eizo Marutani, Naohiro Mori, Fumito Ichinose, Aranya Bagchi, Emanuele Rezoagli, Rajeev Malhotra, Divya Seth, Lorenzo Berra
Publikováno v:
Circulation. 139:815-827
Background: The biological effects of nitric oxide are mediated via protein S-nitrosylation. Levels of S-nitrosylated protein are controlled in part by the denitrosylase, S-nitrosoglutathione reductase (GSNOR). The objective of this study was to exam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b9a41a1190c6ec8b72c3ce625098af5
https://doi.org/10.1161/circulationaha.117.032488
https://doi.org/10.1161/circulationaha.117.032488
Autor:
Maria E Ferrini, Bryan J Simons, David J P Bassett, Matthews O Bradley, Kevan Roberts, Zeina Jaffar
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e70351 (2013)
Allergic asthma is characterized by Th2 type inflammation, leading to airway hyperresponsivenes, mucus hypersecretion and tissue remodeling. S-Nitrosoglutathione reductase (GSNOR) is an alcohol dehydrogenase involved in the regulation of intracellula
Externí odkaz:
https://doaj.org/article/c52d09b814cb4b65a98008ffbd2ef4cb
Publikováno v:
Antisense Research and Development. 3:225-232
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::481328fddbfe357b8e8c45b422ced4b2
https://doi.org/10.1089/ard.1993.3.225
https://doi.org/10.1089/ard.1993.3.225
Publikováno v:
Antisense Research and Development. 3:411-416
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39a281eaab506e358007295a5530b16e
https://doi.org/10.1089/ard.1993.3.411
https://doi.org/10.1089/ard.1993.3.411
Publikováno v:
Annals of the New York Academy of Sciences. 660:124-135
The therapeutic use of antisense DNA has started a revolution in pharmacology. As a model system for demonstrating the therapeutic power of the antisense concept, we sought to interrupt signal transduction in H-ras transformed cells to attempt to dow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1779bf91193b681b7cd6dc8ffed2533
https://doi.org/10.1111/j.1749-6632.1992.tb21065.x
https://doi.org/10.1111/j.1749-6632.1992.tb21065.x
Autor:
Karen R. Leander, Richard D. Storer, Matthews O. Bradley, Srinivasa Prahalada, Matthew J. Van Zwieten, Tamra L. Goodrow
Publikováno v:
Molecular Carcinogenesis. 5:9-15
Inactivating point mutations and small deletions in the p53 tumor suppressor gene have been found in human liver and lung tumor--derived cell lines and tumors. However, little evidence has been reported concerning inactivation or mutation of the p53
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe92b189714bb194b744914f4dfbf2b9
https://doi.org/10.1002/mc.2940050105
https://doi.org/10.1002/mc.2940050105
Autor:
Carole I. Bradt, Sidney M. Hopfer, F.W. Sunderman, Warren W. Nichols, Matthews O. Bradley, Rosina Hill, Andrew R. Kraynak
Publikováno v:
Cancer Genetics and Cytogenetics. 53:57-66
Tissue cultures of tumor cells are frequently utilized to characterize chromosomal changes when direct cytogenetic preparations on tumors fail. The present study demonstrates that chromosomal markers found in direct tumor preparations can become unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76d63cf9cd59091c6f267025f6050c9b
https://doi.org/10.1016/0165-4608(91)90114-a
https://doi.org/10.1016/0165-4608(91)90114-a
Publikováno v:
Mutation Research Letters. 263:9-12
Deuterated and non-deuterated N-nitrosodimethylamine, epichlorohydrin and dimethyl sulfate were evaluated for the ability to induce DNA single-strand breaks in rat hepatocytes as measured by alkaline elution. Non-deuterated nitrosodimethylamine induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::738422f4a63ba1e191b2867a553ce6a2
https://doi.org/10.1016/0165-7992(91)90027-2
https://doi.org/10.1016/0165-7992(91)90027-2
Publikováno v:
Molecular and Cellular Biology. 10:1545-1555
Several lines of evidence have suggested that c-fos may act downstream from c-Ha-ras in a growth-regulatory signal transduction pathway. We used antisense RNA to inhibit c-fos gene expression and investigated the effects of diminished c-fos expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1f22f184611558073771a49c65cb029
https://doi.org/10.1128/mcb.10.4.1545
https://doi.org/10.1128/mcb.10.4.1545
Autor:
Matthews O. Bradley, Antonio C. Wolff, Charles S. Swindell, Forrest Anthony, Sharyn D. Baker, Prabu Devanesan, Ross C. Donehower, Nigel L. Webb, Philip A. Witman
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 74(1-3)
Targeting an anti-cancer drug to tumors should increase the Area Under the drug concentration-time Curve (AUC) in tumors while decreasing the AUC in normal cells and should therefore increase the therapeutic index of that drug. Anti-tumor drugs typic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff8d6d234593a0399065f952adde197c
https://pubmed.ncbi.nlm.nih.gov/11489499
https://pubmed.ncbi.nlm.nih.gov/11489499