Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Matthew W. Leckenby"'
Publikováno v:
Synthetic biology (Oxford, England). 7(1)
Antibiotic resistance genes are widely used to select bacteria transformed with plasmids and to prevent plasmid loss from cultures, yet antibiotics represent contaminants in the biopharmaceutical manufacturing process, and retaining antibiotic resist
Autor:
Matthew W. Leckenby, Wendy Smith, Rocky M. Cranenburgh, Joanne Hulme, Alexandra Elizabeth Bloor, David S. Radford, Susanne Pohl, Colin R. Harwood, Gaurav Bhavsar, Goksel Misirli, Anil Wipat, E. Diane Williamson
Publikováno v:
PROTEOMICS. 13:3298-3308
The use of bacterial systems for recombinant protein production has advantages of simplicity, time and cost over competing systems. However, widely used bacterial expression systems (e.g. Escherichia coli, Pseudomonas fluorescens) are not able to sec
Autor:
Helen S. Atkins, Matthew W. Leckenby, Brendan N. Neeson, Rocky M. Cranenburgh, Abigail M. Spear, E. Diane Williamson
Publikováno v:
Microbial pathogenesis. 46(4)
Live attenuated bacteria provide the potential to replace traditional needle-based vaccination with an orally administered vaccine. The heterologous antigen gene is usually transformed as a multi-copy plasmid into the bacterial cell, but plasmids in
Autor:
Helen S. Garmory, Rocky M. Cranenburgh, Kate F. Griffin, Matthew W. Leckenby, Stephen J. Elvin, Julian A. J. Hanak, Rosa R. Taylor, E. Diane Williamson, M. Gill Hartley
Live, attenuated bacteria are effective vectors for heterologous antigen delivery. However, loss of heterologous gene-bearing plasmids is problematic, and antibiotics and their resistance genes are not desirable for in vivo DNA vaccine delivery due t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18a4a67cfd36df5ac8bb80527e0f6fc9
https://europepmc.org/articles/PMC1087430/
https://europepmc.org/articles/PMC1087430/