Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Matthew W. Klinker"'
Publikováno v:
Frontiers in Immunology, Vol 5 (2014)
Immune suppression mediated by exosomes is an emerging concept with potentially immense utility for immunotherapy in a variety of inflammatory contexts, including allogeneic transplantation. Exosomes containing the apoptosis-inducing molecule Fas lig
Externí odkaz:
https://doaj.org/article/9771db46eb7742d2b7e15596d2380f3c
Publikováno v:
Biotechnology and bioengineeringREFERENCES. 119(2)
Successful clinical translation of mesenchymal stromal cell (MSC) products has not been achieved in the United States and may be in large part due to MSC functional heterogeneity. Efforts have been made to identify 'priming' conditions that produce M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a457e9cb8b8206ff2e4e8ee6f9766df9
https://pubmed.ncbi.nlm.nih.gov/34716713
https://pubmed.ncbi.nlm.nih.gov/34716713
Successful clinical translation of mesenchymal stromal cell (MSC) products has not been achieved in the United States and may be in large part due to MSC functional heterogeneity. Efforts have been made to identify ‘priming’ conditions that produ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::540aa98991544782bf154b326f22bcce
https://doi.org/10.1101/2021.02.23.432501
https://doi.org/10.1101/2021.02.23.432501
Autor:
Elizabeth C. Lessey-Morillon, Ross A. Marklein, Steven R. Bauer, Hannah G. Polikowsky, Katherine A. Drake, Matthew W. Klinker
Publikováno v:
Cytotherapy. 21:17-31
Background Although a preponderance of pre-clinical data demonstrates the immunosuppressive potential of mesenchymal stromal cells (MSCs), significant heterogeneity and lack of critical quality attributes (CQAs) based on immunosuppressive capacity li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebc6ee5ad7116b641aeeff173298c114
https://doi.org/10.1016/j.jcyt.2018.10.008
https://doi.org/10.1016/j.jcyt.2018.10.008
Publikováno v:
Proceedings of the National Academy of Sciences. 114
Human mesenchymal stromal cell (MSC) lines can vary significantly in their functional characteristics, and the effectiveness of MSC-based therapeutics may be realized by finding predictive features associated with MSC function. To identify features a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ae9fe6b729ebc659c58c04edd0bf1c
https://doi.org/10.1073/pnas.1617933114
https://doi.org/10.1073/pnas.1617933114
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 6 (2015)
Frontiers in Immunology, Vol 6 (2015)
Induction of immune tolerance is a key process by which the immune system is educated to modulate reactions against benign stimuli such as self-antigens and commensal microbes. Understanding and harnessing the natural mechanisms of immune tolerance m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b28d331227acc783156919e70b3192d6
https://pubmed.ncbi.nlm.nih.gov/25852690
https://pubmed.ncbi.nlm.nih.gov/25852690
Autor:
Matthew W. Klinker, Cheng-Hong Wei
Publikováno v:
World journal of stem cells. 7(3)
Multipotent mesenchymal stromal cells [also known as mesenchymal stem cells (MSCs)] are currently being studied as a cell-based treatment for inflammatory disorders. Experimental animal models of human immune-mediated diseases have been instrumental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82a21d4a08ce1e1a40fc2da68588b815
https://pubmed.ncbi.nlm.nih.gov/25914763
https://pubmed.ncbi.nlm.nih.gov/25914763
Autor:
Steven K, Lundy, Matthew W, Klinker
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1190
B lymphocytes make several contributions to immune regulation including production of antibodies with regulatory properties, release of immune suppressive cytokines, and expression of death-inducing ligands. A role for Fas ligand (FasL)-expressing "k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a2b661720ab6829149ef346e4d5a77e2
https://pubmed.ncbi.nlm.nih.gov/25015275
https://pubmed.ncbi.nlm.nih.gov/25015275
Autor:
Steven K. Lundy, Matthew W. Klinker
Publikováno v:
Methods in Molecular Biology ISBN: 9781493911608
B lymphocytes make several contributions to immune regulation including production of antibodies with regulatory properties, release of immune suppressive cytokines, and expression of death-inducing ligands. A role for Fas ligand (FasL)-expressing "k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50b937a3a0eaa5205e57f0b9545f0448
https://doi.org/10.1007/978-1-4939-1161-5_7
https://doi.org/10.1007/978-1-4939-1161-5_7
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 5 (2014)
Frontiers in Immunology, Vol 5 (2014)
Immune suppression mediated by exosomes is an emerging concept with potentially immense utility for immunotherapy in a variety of inflammatory contexts, including allogeneic transplantation. Exosomes containing the apoptosis-inducing molecule Fas lig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff2d485d6af76ab2f25a07f167516ab1
https://pubmed.ncbi.nlm.nih.gov/24765093
https://pubmed.ncbi.nlm.nih.gov/24765093