Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Matthew W. Boyce"'
Publikováno v:
Analytical Chemistry. 95:3054-3061
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e21b6f106310e053d0a1a5e4da9ae320
https://doi.org/10.1021/acs.analchem.2c05201
https://doi.org/10.1021/acs.analchem.2c05201
Publikováno v:
Anal Methods
Oxygen is a transcriptional regulator responsible for tissue homeostasis and maintenance. Studies relating cellular phenotype with oxygen tension often use hypoxia chambers, which expose cells to a single, static oxygen tension. Despite their ease of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3bdb503d30c9dc2d18b6a44220f2933
https://doi.org/10.1039/c9ay01690b
https://doi.org/10.1039/c9ay01690b
Autor:
Amanda B. Hummon, Gabriel J. LaBonia, Julie C. McIntosh, Matthew R. Lockett, Matthew W. Boyce, Fernando Tobias
Publikováno v:
Anal Chem
Many potential chemotherapeutics fail to reach patients. One of the key reasons is that compounds are tested during the drug discovery stage in two-dimensional (2D) cell cultures, which are often unable to accurately model in vivo outcomes. Three-dim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95d0f4c93713d0bbfa73f46477c183e8
https://doi.org/10.1021/acs.analchem.9b03536
https://doi.org/10.1021/acs.analchem.9b03536
Autor:
Brenden P. Kromhout, Nathan A. Whitman, Matthew R. Lockett, Rachael M. Kenney, Matthew W. Boyce
Publikováno v:
Analytical Chemistry. 90:2376-2383
Paper-based cultures are an emerging platform for preparing 3D tissue-like structures. Chemical gradients can be imposed upon these cultures, generating microenvironments similar to those found in poorly vascularized tumors. There is increasing evide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::308499b6ad78bd93d35388a7a2f36ee0
https://doi.org/10.1021/acs.analchem.7b05015
https://doi.org/10.1021/acs.analchem.7b05015
Publikováno v:
Current Protocols in Chemical Biology
To elucidate the chemical and environmental conditions that promote invasion of cancer cells, an assay is needed in which the chemical landscape of a tumor-like environment can be experimentally manipulated and probed. The three-dimensional paper-bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7db4c020eec44558c57bca45dc46fca6
https://doi.org/10.1002/cpch.22
https://doi.org/10.1002/cpch.22
Publikováno v:
The Analyst. 142:2819-2827
In vitro models for screening new cancer chemotherapeutics often rely on two-dimensional cultures to predict therapeutic potential. Unfortunately, the predictive power of these models is limited, as they fail to recapitulate the complex three-dimensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef32f39425988950c9910b3785ed3bc7
https://doi.org/10.1039/c7an00806f
https://doi.org/10.1039/c7an00806f
Publikováno v:
The Analyst. 141:661-668
Cellular migration is the movement of cells, cultured as a monolayer; cellular invasion is similar to migration, but requires the cells to move through a three-dimensional material such as basement membrane extract or a synthetic hydrogel. Migration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35421d3a69b9f268d35ff1dbc63d4a04
https://doi.org/10.1039/c5an01787d
https://doi.org/10.1039/c5an01787d
Publikováno v:
Analytical and Bioanalytical Chemistry. 408:2985-2992
Paper-based scaffolds are an attractive material for generating 3D tissue-like cultures because paper is readily available and does not require specialized equipment to pattern, cut, or use. By controlling the exchange of fresh culture medium with th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a60f6fe8a74f6f2d3771bf8f695857
https://doi.org/10.1007/s00216-015-9189-x
https://doi.org/10.1007/s00216-015-9189-x
Publikováno v:
Current protocols in chemical biology. 9(2)
To elucidate the chemical and environmental conditions that promote invasion of cancer cells, an assay is needed in which the chemical landscape of a tumor-like environment can be experimentally manipulated and probed. The three-dimensional paper-bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::77ec985900b857f1a9dac58bce8d66f6
https://pubmed.ncbi.nlm.nih.gov/28628202
https://pubmed.ncbi.nlm.nih.gov/28628202