Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Matthew W Parker"'
Publikováno v:
eLife, Vol 11 (2022)
Type II topoisomerases modulate chromosome supercoiling, condensation, and catenation by moving one double-stranded DNA segment through a transient break in a second duplex. How DNA strands are chosen and selectively passed to yield appropriate topol
Externí odkaz:
https://doaj.org/article/36b1c469ac8a4f57ab6662d071625808
Publikováno v:
eLife, Vol 10 (2021)
Liquid–liquid phase separation (LLPS) of intrinsically disordered regions (IDRs) in proteins can drive the formation of membraneless compartments in cells. Phase-separated structures enrich for specific partner proteins and exclude others. Previous
Externí odkaz:
https://doaj.org/article/b5e0dc26df444e4a9bcc3f297744c585
Autor:
Matthew W Parker, Maren Bell, Mustafa Mir, Jonchee A Kao, Xavier Darzacq, Michael R Botchan, James M Berger
Publikováno v:
eLife, Vol 8 (2019)
The initiation of DNA replication in metazoans occurs at thousands of chromosomal sites known as origins. At each origin, the Origin Recognition Complex (ORC), Cdc6, and Cdt1 co-assemble to load the Mcm2-7 replicative helicase onto chromatin. Current
Externí odkaz:
https://doaj.org/article/3b730dc3b725431c82d085509fb2026f
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49177 (2012)
Neuropilin (Nrp) receptors function as essential cell surface receptors for the Vascular Endothelial Growth Factor (VEGF) family of proangiogenic cytokines and the semaphorin 3 (Sema3) family of axon guidance molecules. There are two Nrp homologues,
Externí odkaz:
https://doaj.org/article/096fef39feeb4d59a257e5fcd005d4f8
Autor:
P. Hendrik Pretorius, Junchi Liu, Kesava S. Kalluri, Yulei Jiang, Jeffery A. Leppo, Seth T. Dahlberg, Janusz Kikut, Matthew W. Parker, Friederike K. Keating, Robert Licho, Benjamin Auer, Clifford Lindsay, Arda Konik, Yongyi Yang, Miles N. Wernick, Michael A. King
Publikováno v:
Journal of Nuclear Cardiology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74ec57adf84002db1f356985f377c645
https://doi.org/10.1007/s12350-023-03295-3
https://doi.org/10.1007/s12350-023-03295-3
The first step towards eukaryotic genome duplication is loading of the replicative helicase, the Mcm2-7 complex, onto chromatin. This so-called “licensing” step is executed by the Pre-Replication Complex (Pre-RC) whose assembly on chromatin is nu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1991da07b4c9b46eae96b744a86ac687
https://doi.org/10.1101/2023.05.11.540405
https://doi.org/10.1101/2023.05.11.540405
Protein sequences can be broadly categorized into two classes: those which adopt stable secondary structure and fold into a domain (i.e., globular proteins), and those that do not. This latter class of sequences are conformationally heterogeneous and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49d48f3f6922c274f707068665285576
https://doi.org/10.1101/2023.05.10.539862
https://doi.org/10.1101/2023.05.10.539862
Publikováno v:
Journal of the American Society of Echocardiography. 35:275-277
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ddbaa0516a2c1b67cef8d34c293e7da
https://doi.org/10.1016/j.echo.2021.12.001
https://doi.org/10.1016/j.echo.2021.12.001
Autor:
Matthew W. Parker, Gerard P. Aurigemma, Summer Aldrugh, Colleen Harrington, Jorge Escobar Valle
Publikováno v:
The American Journal of Cardiology. 150:89-94
It is generally assumed that left ventricular (LV) hypertrophy in aortic stenosis (AS) is a compensatory adaptation to chronic outflow obstruction. The advent of transcutaneous aortic valve replacement has stimulated more focus on AS in older patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43d30089d234afa1ba07864f5bea8b5a
https://doi.org/10.1016/j.amjcard.2021.03.036
https://doi.org/10.1016/j.amjcard.2021.03.036