Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Matthew W Motley"'
Autor:
Terence P Gade, Matthew W Motley, Bradley J Beattie, Roshni Bhakta, Adele L Boskey, Jason A Koutcher, Philipp Mayer-Kuckuk
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22608 (2011)
The purpose of this study was to develop a paradigm for quantitative molecular imaging of bone cell activity. We hypothesized the feasibility of non-invasive imaging of the osteoblast enzyme alkaline phosphatase (ALP) using a small imaging molecule i
Externí odkaz:
https://doaj.org/article/19d9e6cc6ddf4211a5fe59e215741ecf
Publikováno v:
The Journal of Physical Chemistry B. 119:3662-3668
Recent studies of the bacterial enzymes EcMTAN and VcMTAN showed that they have different binding affinities for the same transition state analogue. This was surprising given the similarity of their active sites. We performed transition path sampling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff7e1cfebc21a715711173ec956bd84a
https://doi.org/10.1021/jp511983h
https://doi.org/10.1021/jp511983h
Autor:
Ian M. Buchanan, Jason A. Koutcher, Matthew W. Motley, William M. Spees, Terence P. Gade, Yousef Mazaheri
Publikováno v:
Clinical Cancer Research. 15:247-255
Purpose: Low–molecular weight (LMW) chemotherapeutics are believed to reach tumors through diffusion across capillary beds as well as membrane transporters. Unexpectedly, the delivery of these agents seems to be augmented by reductions in tumor int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e39ea9dcd8d2b32be03747d98446311
https://doi.org/10.1158/1078-0432.ccr-08-0611
https://doi.org/10.1158/1078-0432.ccr-08-0611
Publikováno v:
The journal of physical chemistry. B. 117(33)
Transition-state analogues of bacterial 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidases (MTANs) disrupt quorum-sensing pathways in Escherichia coli and Vibrio cholerae, demonstrating the potential to limit pathogenicity without placing ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1352773622b42b8b642f243752a7efb3
https://pubmed.ncbi.nlm.nih.gov/23895500
https://pubmed.ncbi.nlm.nih.gov/23895500
Autor:
Bradley J. Beattie, Jason A. Koutcher, Matthew W. Motley, Terence P. Gade, Philipp Mayer-Kuckuk, Roshni Bhakta, Adele L. Boskey
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 7, p e22608 (2011)
PLoS ONE, Vol 6, Iss 7, p e22608 (2011)
The purpose of this study was to develop a paradigm for quantitative molecular imaging of bone cell activity. We hypothesized the feasibility of non-invasive imaging of the osteoblast enzyme alkaline phosphatase (ALP) using a small imaging molecule i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70957ef0cd5c7bf426b878b873049599
https://pubmed.ncbi.nlm.nih.gov/21799916
https://pubmed.ncbi.nlm.nih.gov/21799916