Zobrazeno 1 - 10
of 244
pro vyhledávání: '"Matthew W Hahn"'
Autor:
Lucie A Bergeron, Søren Besenbacher, Tychele Turner, Cyril J Versoza, Richard J Wang, Alivia Lee Price, Ellie Armstrong, Meritxell Riera, Jedidiah Carlson, Hwei-yen Chen, Matthew W Hahn, Kelley Harris, April Snøfrid Kleppe, Elora H López-Nandam, Priya Moorjani, Susanne P Pfeifer, George P Tiley, Anne D Yoder, Guojie Zhang, Mikkel H Schierup
Publikováno v:
eLife, Vol 11 (2022)
In the past decade, several studies have estimated the human per-generation germline mutation rate using large pedigrees. More recently, estimates for various nonhuman species have been published. However, methodological differences among studies in
Externí odkaz:
https://doaj.org/article/d731add1c7b74d45809114cfd96ce456
Autor:
Mark S Hibbins, Matthew W Hahn
Publikováno v:
PLoS Genetics, Vol 17, Iss 11, p e1009892 (2021)
It is now understood that introgression can serve as powerful evolutionary force, providing genetic variation that can shape the course of trait evolution. Introgression also induces a shared evolutionary history that is not captured by the species p
Externí odkaz:
https://doaj.org/article/71803bbefe1f47018779e0c3c509a489
Autor:
Dan Vanderpool, Bui Quang Minh, Robert Lanfear, Daniel Hughes, Shwetha Murali, R Alan Harris, Muthuswamy Raveendran, Donna M Muzny, Mark S Hibbins, Robert J Williamson, Richard A Gibbs, Kim C Worley, Jeffrey Rogers, Matthew W Hahn
Publikováno v:
PLoS Biology, Vol 18, Iss 12, p e3000954 (2020)
Our understanding of the evolutionary history of primates is undergoing continual revision due to ongoing genome sequencing efforts. Bolstered by growing fossil evidence, these data have led to increased acceptance of once controversial hypotheses re
Externí odkaz:
https://doaj.org/article/89333266269f4ef186dfa850792cc133
Publikováno v:
eLife, Vol 9 (2020)
The incongruence of character states with phylogenetic relationships is often interpreted as evidence of convergent evolution. However, trait evolution along discordant gene trees can also generate these incongruences – a phenomenon known as hemipl
Externí odkaz:
https://doaj.org/article/dbdaeb4e0a8c484a84e432aeba7cca7b
Publikováno v:
eLife, Vol 7 (2018)
We present a multispecies coalescent model for quantitative traits that allows for evolutionary inferences at micro- and macroevolutionary scales. A major advantage of this model is its ability to incorporate genealogical discordance underlying a qua
Externí odkaz:
https://doaj.org/article/57f254c7ded2424797b044b9254d8c4b
Autor:
Wazim Mohammed Ismail, Kymberleigh A Pagel, Vikas Pejaver, Simo V Zhang, Sofia Casasa, Matthew Mort, David N Cooper, Matthew W Hahn, Predrag Radivojac
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0208901 (2018)
Recent genetic studies and whole-genome sequencing projects have greatly improved our understanding of human variation and clinically actionable genetic information. Smaller ethnic populations, however, remain underrepresented in both individual and
Externí odkaz:
https://doaj.org/article/b7f550463eb9492787f2c91e9feb7399
Autor:
Raiyan R. Khan, Rafael F. Guerrero, Ronald J. Wapner, Matthew W. Hahn, Anita Raja, Ansaf Salleb-Aouissi, William A. Grobman, Hyagriv Simhan, Robert M. Silver, Judith H. Chung, Uma M. Reddy, Predrag Radivojac, Itsik Pe’er, David M. Haas
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Adverse pregnancy outcomes (APOs) affect a large proportion of pregnancies and represent an important cause of morbidity and mortality worldwide. Yet the pathophysiology of APOs is poorly understood, limiting our ability to prevent and treat
Externí odkaz:
https://doaj.org/article/3d4e841d56df4a31ba7c73f2e48f8b88
Publikováno v:
PLoS Biology, Vol 14, Iss 2, p e1002379 (2016)
Speciation events often occur in rapid bursts of diversification, but the ecological and genetic factors that promote these radiations are still much debated. Using whole transcriptomes from all 13 species in the ecologically and reproductively diver
Externí odkaz:
https://doaj.org/article/0c54f8eb075e421f90068c5ffacf427a
Autor:
James F Denton, Jose Lugo-Martinez, Abraham E Tucker, Daniel R Schrider, Wesley C Warren, Matthew W Hahn
Publikováno v:
PLoS Computational Biology, Vol 10, Iss 12, p e1003998 (2014)
Current sequencing methods produce large amounts of data, but genome assemblies based on these data are often woefully incomplete. These incomplete and error-filled assemblies result in many annotation errors, especially in the number of genes presen
Externí odkaz:
https://doaj.org/article/0b216e1a0c1c46c4be623ff05c2570e2
Autor:
Doris Bachtrog, Judith E Mank, Catherine L Peichel, Mark Kirkpatrick, Sarah P Otto, Tia-Lynn Ashman, Matthew W Hahn, Jun Kitano, Itay Mayrose, Ray Ming, Nicolas Perrin, Laura Ross, Nicole Valenzuela, Jana C Vamosi, Tree of Sex Consortium
Publikováno v:
PLoS Biology, Vol 12, Iss 7, p e1001899 (2014)
Sexual reproduction is an ancient feature of life on earth, and the familiar X and Y chromosomes in humans and other model species have led to the impression that sex determination mechanisms are old and conserved. In fact, males and females are dete
Externí odkaz:
https://doaj.org/article/fb9f59194e90424999b892f20ca969f6