Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Matthew V. Cannon"'
Autor:
Emily M. Ringwalt, Mark A. Currier, Andrea M. Glaspell, Chun-Yu Chen, Matthew V. Cannon, Maren Cam, Amy C. Gross, Matthew Gust, Pin-Yi Wang, Louis Boon, Laura E. Biederman, Emily Schwarz, Prajwal Rajappa, Dean A. Lee, Elaine R. Mardis, William E. Carson, 3rd, Ryan D. Roberts, Timothy P. Cripe
Publikováno v:
Molecular Therapy: Oncology, Vol 32, Iss 4, Pp 200886- (2024)
We previously reported that the DNA alkylator and transcriptional-blocking chemotherapeutic agent trabectedin enhances oncolytic herpes simplex viroimmunotherapy in human sarcoma xenograft models, though the mechanism remained to be elucidated. Here
Externí odkaz:
https://doaj.org/article/9f97543ab8ef4ba1b69298b70f6f6188
Autor:
Sanjana Rajan, Emily M. Franz, Camille A. McAloney, Tatyana A. Vetter, Maren Cam, Amy C. Gross, Cenny Taslim, Meng Wang, Matthew V. Cannon, Alexander Oles, Ryan D. Roberts
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-18 (2023)
Abstract Background Tumors are complex tissues containing collections of phenotypically diverse malignant and nonmalignant cells. We know little of the mechanisms that govern heterogeneity of tumor cells nor of the role heterogeneity plays in overcom
Externí odkaz:
https://doaj.org/article/f3bd873dccee4b43a8ac192346072f84
Autor:
Sarah Watson, Collette A. LaVigne, Lin Xu, Didier Surdez, Joanna Cyrta, Delia Calderon, Matthew V. Cannon, Matthew R. Kent, Katherine M. Silvius, Jack P. Kucinski, Emma N. Harrison, Whitney Murchison, Dinesh Rakheja, Franck Tirode, Olivier Delattre, James F. Amatruda, Genevieve C. Kendall
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 112013- (2023)
Summary: Clinical sequencing efforts are rapidly identifying sarcoma gene fusions that lack functional validation. An example is the fusion of transcriptional coactivators, VGLL2-NCOA2, found in infantile rhabdomyosarcoma. To delineate VGLL2-NCOA2 tu
Externí odkaz:
https://doaj.org/article/fdc0828e193b44cf881e6eb5e4a6a484
Autor:
Haikel N. Bogale, Matthew V. Cannon, Kalil Keita, Denka Camara, Yaya Barry, Moussa Keita, Drissa Coulibaly, Abdoulaye K. Kone, Ogobara K. Doumbo, Mahamadou A. Thera, Christopher V. Plowe, Mark Travassos, Seth Irish, David Serre
Publikováno v:
Parasites & Vectors, Vol 13, Iss 1, Pp 1-13 (2020)
Abstract Background The commensal microbiota of mosquitoes impacts their development, immunity, and competency, and could provide a target for alternative entomological control approaches. However, despite the importance of the mosquito/microbiota in
Externí odkaz:
https://doaj.org/article/5b5a2ed1ba0643598256ee75032f60ec
Autor:
Matthew V. Cannon, Haikel N. Bogale, Devika Bhalerao, Kalil Keita, Denka Camara, Yaya Barry, Moussa Keita, Drissa Coulibaly, Abdoulaye K. Kone, Ogobara K. Doumbo, Mahamadou A. Thera, Christopher V. Plowe, Mark A. Travassos, Seth R. Irish, Joshua Yeroshefsky, Jeannine Dorothy, Brian Prendergast, Brandyce St. Laurent, Megan L. Fritz, David Serre
Publikováno v:
Biology Open, Vol 10, Iss 7 (2021)
Vector-borne pathogens cause many human infectious diseases and are responsible for high mortality and morbidity throughout the world. They can also cause livestock epidemics with dramatic social and economic consequences. Due to its high costs, vect
Externí odkaz:
https://doaj.org/article/d80123cde60e451388d4677e53cf26e4
Autor:
Matthew V. Cannon, Haikel Bogale, Lindsay Rutt, Michael Humphrys, Poonum Korpe, Priya Duggal, Jacques Ravel, David Serre
Publikováno v:
Microbiome, Vol 6, Iss 1, Pp 1-11 (2018)
Abstract Background Several of the most devastating human diseases are caused by eukaryotic parasites transmitted by arthropod vectors or through food and water contamination. These pathogens only represent a fraction of all unicellular eukaryotes an
Externí odkaz:
https://doaj.org/article/d86dbc1987984670b000ba90dc0f1cf8
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 11, Pp 3701-3709 (2016)
DNA methylation is traditionally thought to be established during early development and to remain mostly unchanged thereafter in healthy tissues, although recent studies have shown that this epigenetic mark can be more dynamic. Epigenetic changes occ
Externí odkaz:
https://doaj.org/article/79c6569e7a8f47afb9eaafebc7d05cf9
Autor:
Jean Popovici, Lindsey R. Friedrich, Saorin Kim, Sophalai Bin, Vorleak Run, Dysoley Lek, Matthew V. Cannon, Didier Menard, David Serre
Publikováno v:
mBio, Vol 9, Iss 1 (2018)
ABSTRACT Plasmodium vivax parasites have a unique dormant stage that can cause relapses weeks or months after the initial infection. These dormant parasites are among the main challenges of vivax malaria control as they constitute a reservoir that is
Externí odkaz:
https://doaj.org/article/aac760fb5ecc4580876de15120f38ccd
Autor:
Sanjana Rajan, Simone Zaccaria, Matthew V. Cannon, Maren Cam, Amy C. Gross, Benjamin J. Raphael, Ryan D. Roberts
Publikováno v:
Cancer Research Communications. 3:564-575
Osteosarcoma is an aggressive malignancy characterized by high genomic complexity. Identification of few recurrent mutations in protein coding genes suggests that somatic copy-number aberrations (SCNA) are the genetic drivers of disease. Models aroun
Autor:
Matthew R. Kent, Delia Calderon, Katherine M. Silvius, Jack P. Kucinski, Collette A. LaVigne, Matthew V. Cannon, Genevieve C. Kendall
Publikováno v:
Developmental Biology. 496:1-14