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pro vyhledávání: '"Matthew Torrington"'
Autor:
Matthew Torrington
Publikováno v:
Oxford Medicine
This chapter discusses the DSM-5 diagnostic criteria for substance use disorders and identifies addiction as a disease of reward, motivation, and memory rooted in complex biologic changes. It explains the epidemiology of addiction and identifies the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a5de954e9d27ddbed7734b561ff7e72
https://doi.org/10.1093/med/9780190275334.003.0001
https://doi.org/10.1093/med/9780190275334.003.0001
Autor:
Matthew Torrington
Publikováno v:
Oxford Medicine
This chapter traces the history of drug and alcohol use in America, starting in the 1850s through Prohibition, the emergence of Alcoholics Anonymous in 1935, and the treatment evolution around the 1950s. It reviews the US Drug Policy in the 1970s, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::518af2fc1d45c33effcd379bbbe19f68
https://doi.org/10.1093/med/9780190275334.003.0002
https://doi.org/10.1093/med/9780190275334.003.0002
Publikováno v:
Oxford Medicine
Sedatives, hypnotics, and anxiolytics are CNS depressants with GABAergic activity that are potentially habit-forming due to their activity in brain reward pathways. They are central in the drug overdose epidemic with benzodiazepines (BZD) being invol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed5425761e5e743ea7258765abd6ab24
https://doi.org/10.1093/med/9780190275334.003.0005
https://doi.org/10.1093/med/9780190275334.003.0005
Autor:
Walter Ling, Matthew Torrington
Publikováno v:
Oxford Medicine
This chapter defines terms such as “opiate” and “opioid” and explains their physiological functions as agonist, antagonist, and partial agonist. It notes the long history of medicinal opioid use for acute pain, as well as the curse of addicti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73603bc5356a02b97d6208c06cd49c18
https://doi.org/10.1093/med/9780190275334.003.0008
https://doi.org/10.1093/med/9780190275334.003.0008
Publikováno v:
Neuropsychiatry. 3:535-543
Buprenorphine is a partial opioid agonist at the m receptor and is used as a daily-dose sublingual tablet or filmstrip for managing opioid addiction. In the United States, the Drug Addiction Treatment Act of 2000 made buprenorphine the only opioid me
Publikováno v:
Substance Abuse and Rehabilitation
Substance abuse and rehabilitation, vol 2, iss 1
Substance abuse and rehabilitation, vol 2, iss 1
Pharmacotherapies for opioid addiction under active development in the US include lofexidine (primarily for managing withdrawal symptoms) and Probuphine®, a distinctive mode of delivering buprenorphine for six months, thus relieving patients, clinic
Publikováno v:
Journal of Addictive Diseases. 26:93-99
This clinical observation provides a first look at differences between two patient subgroups, prescription opiate (PO) abusers and heroin abusers, presenting for office-based buprenorphine treatment. Medical and drug use histories, medication dose, t
Autor:
Eshetu Tefera, Crna Charles Griffis, Matthew Torrington, Elizabeth C. Breen, BS Ryan Sadakane, RN Peggy Compton, Michael R. Irwin
Publikováno v:
Journal of opioid management, vol 11, iss 2
Objective: To determine the independent and combined effects of pain and opioids on the activation of an early marker of inflammation, nuclear factor- κ B (NF- κ B). Design: NF- κ B activation was compared within-subjects following four randomly o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3178c80d394cb585ff15f1239b83f941
https://europepmc.org/articles/PMC4507428/
https://europepmc.org/articles/PMC4507428/
Autor:
Jessica Jenkins, Larissa J. Mooney, S. Reed, M. Olaer, Maureen Hillhouse, J. Hernandez, Walter Ling, Matthew Torrington, Daniel L. Dickerson
Publikováno v:
Drug and Alcohol Dependence. 146:e180-e181
Autor:
Walter Ling, Christopher Chapleo, Maureen Hillhouse, Karen Miotto, Matthew Torrington, Jessica Jenkins
Publikováno v:
Journal of addiction medicine. 6(2)
Opioids are the most effective pain medication available, yet concerns about their safety may limit their administration to those in need. In efforts to identify analgesics with lower potential for abuse and dependence, recent evidence suggests that